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Protein
Submitted name:

TrwB

Gene

trwB

Organism
Escherichia coli
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei124ADPCombined sources1
Binding sitei124ATP analogCombined sources1
Binding sitei375ADPCombined sources1
Binding sitei375ATP analogCombined sources1
Binding sitei494ATP analogCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi131 – 138ADPCombined sources8
Nucleotide bindingi133 – 138ATP analogCombined sources6

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Nucleotide-bindingCombined sources

Protein family/group databases

TCDBi3.A.7.2.1. the type iv (conjugal dna-protein transfer or virb) secretory pathway (ivsp) family.

Names & Taxonomyi

Protein namesi
Submitted name:
TrwBImported
Submitted name:
TrwB proteinImported
Gene namesi
Name:trwBImported
Encoded oniPlasmid R388Imported
OrganismiEscherichia coliImported
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalSequence analysisAdd BLAST20
Transmembranei52 – 71HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

DIPiDIP-16926N.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1E9RX-ray2.40A/B/D/E/F/G71-507[»]
1E9SX-ray2.50A/B/D/E/F/G/H/I/J/K/L/M71-507[»]
1GKIX-ray3.00A/B/D/E/F/G71-507[»]
1GL6X-ray2.80A/B/D/E/F/G72-507[»]
1GL7X-ray3.00A/B/D/E/F/G71-507[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini110 – 490TrwB_AAD_bindInterPro annotationAdd BLAST381

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR027417. P-loop_NTPase.
IPR019476. T4SS_TraD_DNA-bd.
[Graphical view]
PfamiPF10412. TrwB_AAD_bind. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04230-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPDDQRKVS AGIVIVLPLI FWITAVQKTE VLGSPKLLAL WELMKLTPQK
60 70 80 90 100
PILLLSALGG LAVGVLFVWL LNSVGQGEFG GAPFKRFLRG TRIVSGGKLK
110 120 130 140 150
RMTREKAKQV TVAGVPMPRD AEPRHLLVNG ATGTGKSVLL RELAYTGLLR
160 170 180 190 200
GDRMVIVDPN GDMLSKFGRD KDIILNPYDQ RTKGWSFFNE IRNDYDWQRY
210 220 230 240 250
ALSVVPRGKT DEAEEWASYG RLLLRETAKK LALIGTPSMR ELFHWTTIAT
260 270 280 290 300
FDDLRGFLEG TLAESLFAGS NEASKALTSA RFVLSDKLPE HVTMPDGDFS
310 320 330 340 350
IRSWLEDPNG GNLFITWRED MGPALRPLIS AWVDVVCTSI LSLPEEPKRR
360 370 380 390 400
LWLFIDELAS LEKLASLADA LTKGRKAGLR VVAGLQSTSQ LDDVYGVKEA
410 420 430 440 450
QTLRASFRSL VVLGGSRTDP KTNEDMSLSL GEHEVERDRY SKNTGKHHST
460 470 480 490 500
GRALERVRER VVMPAEIANL PDLTAYVGFA GNRPIAKVPL EIKQFANRQP

AFVEGTI
Length:507
Mass (Da):56,273
Last modified:November 1, 1996 - v1
Checksum:iA80196C24CA71EAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63150 Genomic DNA. Translation: CAA44852.1.
BR000038 Genomic DNA. Translation: FAA00040.1.
PIRiS43877.
RefSeqiYP_009182120.1. NC_028464.1.

Genome annotation databases

GeneIDi29200594.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63150 Genomic DNA. Translation: CAA44852.1.
BR000038 Genomic DNA. Translation: FAA00040.1.
PIRiS43877.
RefSeqiYP_009182120.1. NC_028464.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1E9RX-ray2.40A/B/D/E/F/G71-507[»]
1E9SX-ray2.50A/B/D/E/F/G/H/I/J/K/L/M71-507[»]
1GKIX-ray3.00A/B/D/E/F/G71-507[»]
1GL6X-ray2.80A/B/D/E/F/G72-507[»]
1GL7X-ray3.00A/B/D/E/F/G71-507[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-16926N.

Protein family/group databases

TCDBi3.A.7.2.1. the type iv (conjugal dna-protein transfer or virb) secretory pathway (ivsp) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi29200594.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR027417. P-loop_NTPase.
IPR019476. T4SS_TraD_DNA-bd.
[Graphical view]
PfamiPF10412. TrwB_AAD_bind. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ04230_ECOLX
AccessioniPrimary (citable) accession number: Q04230
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, PlasmidImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.