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Protein
Submitted name:

TrwB

Gene

trwB

Organism
Escherichia coli
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei124 – 1241ADPCombined sources
Binding sitei124 – 1241ATP analogCombined sources
Binding sitei375 – 3751ADPCombined sources
Binding sitei375 – 3751ATP analogCombined sources
Binding sitei494 – 4941ATP analogCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi131 – 1388ADPCombined sources
Nucleotide bindingi133 – 1386ATP analogCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Nucleotide-bindingCombined sources

Protein family/group databases

TCDBi3.A.7.2.1. the type iv (conjugal dna-protein transfer or virb) secretory pathway (ivsp) family.

Names & Taxonomyi

Protein namesi
Submitted name:
TrwBImported
Submitted name:
TrwB proteinImported
Gene namesi
Name:trwBImported
Encoded oniPlasmid R388Imported
OrganismiEscherichia coliImported
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3120HelicalSequence analysisAdd
BLAST
Transmembranei52 – 7120HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

DIPiDIP-16926N.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1E9RX-ray2.40A/B/D/E/F/G71-507[»]
1E9SX-ray2.50A/B/D/E/F/G/H/I/J/K/L/M71-507[»]
1GKIX-ray3.00A/B/D/E/F/G71-507[»]
1GL6X-ray2.80A/B/D/E/F/G72-507[»]
1GL7X-ray3.00A/B/D/E/F/G71-507[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini110 – 490381TrwB_AAD_bindInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR027417. P-loop_NTPase.
IPR019476. T4SS_TraD_DNA-bd.
[Graphical view]
PfamiPF10412. TrwB_AAD_bind. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04230-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPDDQRKVS AGIVIVLPLI FWITAVQKTE VLGSPKLLAL WELMKLTPQK
60 70 80 90 100
PILLLSALGG LAVGVLFVWL LNSVGQGEFG GAPFKRFLRG TRIVSGGKLK
110 120 130 140 150
RMTREKAKQV TVAGVPMPRD AEPRHLLVNG ATGTGKSVLL RELAYTGLLR
160 170 180 190 200
GDRMVIVDPN GDMLSKFGRD KDIILNPYDQ RTKGWSFFNE IRNDYDWQRY
210 220 230 240 250
ALSVVPRGKT DEAEEWASYG RLLLRETAKK LALIGTPSMR ELFHWTTIAT
260 270 280 290 300
FDDLRGFLEG TLAESLFAGS NEASKALTSA RFVLSDKLPE HVTMPDGDFS
310 320 330 340 350
IRSWLEDPNG GNLFITWRED MGPALRPLIS AWVDVVCTSI LSLPEEPKRR
360 370 380 390 400
LWLFIDELAS LEKLASLADA LTKGRKAGLR VVAGLQSTSQ LDDVYGVKEA
410 420 430 440 450
QTLRASFRSL VVLGGSRTDP KTNEDMSLSL GEHEVERDRY SKNTGKHHST
460 470 480 490 500
GRALERVRER VVMPAEIANL PDLTAYVGFA GNRPIAKVPL EIKQFANRQP

AFVEGTI
Length:507
Mass (Da):56,273
Last modified:November 1, 1996 - v1
Checksum:iA80196C24CA71EAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63150 Genomic DNA. Translation: CAA44852.1.
BR000038 Genomic DNA. Translation: FAA00040.1.
PIRiS43877.
RefSeqiYP_009182120.1. NC_028464.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63150 Genomic DNA. Translation: CAA44852.1.
BR000038 Genomic DNA. Translation: FAA00040.1.
PIRiS43877.
RefSeqiYP_009182120.1. NC_028464.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1E9RX-ray2.40A/B/D/E/F/G71-507[»]
1E9SX-ray2.50A/B/D/E/F/G/H/I/J/K/L/M71-507[»]
1GKIX-ray3.00A/B/D/E/F/G71-507[»]
1GL6X-ray2.80A/B/D/E/F/G72-507[»]
1GL7X-ray3.00A/B/D/E/F/G71-507[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-16926N.

Protein family/group databases

TCDBi3.A.7.2.1. the type iv (conjugal dna-protein transfer or virb) secretory pathway (ivsp) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR027417. P-loop_NTPase.
IPR019476. T4SS_TraD_DNA-bd.
[Graphical view]
PfamiPF10412. TrwB_AAD_bind. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ04230_ECOLX
AccessioniPrimary (citable) accession number: Q04230
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, PlasmidImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.