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Protein
Submitted name:

Oncogene tyrosine protein kinase receptor

Gene

trk4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • transmembrane receptor protein tyrosine kinase activity Source: UniProtKB

GO - Biological processi

  • peptidyl-tyrosine phosphorylation Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, ReceptorImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Oncogene tyrosine protein kinase receptorImported
Gene namesi
Name:trk4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ04227.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000431418.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili3 – 3331Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IMMI. Eukaryota.
ENOG410XTGG. LUCA.

Sequencei

Sequence statusi: Fragment.

Q04227-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HSIKDVHARL QALAQEQEEE EQEQEEQEGE EAATPSGGGR NRSASSSWVG
60 70 80 90 100
TMAGISMSLH FMTLGGSSLS PTEGKGSGLQ GHIIENPQYF SDACVHHIKR
110
RDIVLKWELG EGAFGKVF
Length:118
Mass (Da):12,822
Last modified:November 1, 1996 - v1
Checksum:i1A31CD3D1D9A8A0C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei118 – 1181Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55337 mRNA. Translation: AAA36769.1.
PIRiI77386.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55337 mRNA. Translation: AAA36769.1.
PIRiI77386.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000431418.

Proteomic databases

PaxDbiQ04227.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IMMI. Eukaryota.
ENOG410XTGG. LUCA.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Human trk oncogenes activated by point mutation, in-frame deletion, and duplication of the tyrosine kinase domain."
    Coulier F., Kumar R., Ernst M., Klein R., Martin-Zanca D., Barbacid M.
    Mol. Cell. Biol. 10:4202-4210(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ04227_HUMAN
AccessioniPrimary (citable) accession number: Q04227
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 11, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.