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Protein
Submitted name:

Oncogene tyrosine protein kinase receptor

Gene

trk4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. transmembrane receptor protein tyrosine kinase activity Source: UniProtKB

GO - Biological processi

  1. peptidyl-tyrosine phosphorylation Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, ReceptorImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Oncogene tyrosine protein kinase receptorImported
Gene namesi
Name:trk4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Sequencei

Sequence statusi: Fragment.

Q04227-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HSIKDVHARL QALAQEQEEE EQEQEEQEGE EAATPSGGGR NRSASSSWVG
60 70 80 90 100
TMAGISMSLH FMTLGGSSLS PTEGKGSGLQ GHIIENPQYF SDACVHHIKR
110
RDIVLKWELG EGAFGKVF
Length:118
Mass (Da):12,822
Last modified:November 1, 1996 - v1
Checksum:i1A31CD3D1D9A8A0C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei118 – 1181Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55337 mRNA. Translation: AAA36769.1.
PIRiI77386.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55337 mRNA. Translation: AAA36769.1.
PIRiI77386.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Human trk oncogenes activated by point mutation, in-frame deletion, and duplication of the tyrosine kinase domain."
    Coulier F., Kumar R., Ernst M., Klein R., Martin-Zanca D., Barbacid M.
    Mol. Cell. Biol. 10:4202-4210(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ04227_HUMAN
AccessioniPrimary (citable) accession number: Q04227
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.