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Protein

Probable metabolite transport protein YDR387C

Gene

YDR387C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • glucose import Source: GO_Central
  • hexose transmembrane transport Source: GO_Central
  • transmembrane transport Source: SGD
  • transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29935-MONOMER.
ReactomeiR-SCE-428790. Facilitative Na+-independent glucose transporters.
R-SCE-429593. Inositol transporters.
R-SCE-8856825. Cargo recognition for clathrin-mediated endocytosis.

Protein family/group databases

TCDBi2.A.1.1.101. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Probable metabolite transport protein YDR387C
Gene namesi
Ordered Locus Names:YDR387C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR387C.
SGDiS000002795. YDR387C.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 39CytoplasmicSequence analysisAdd BLAST39
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Topological domaini61 – 83ExtracellularSequence analysisAdd BLAST23
Transmembranei84 – 104HelicalSequence analysisAdd BLAST21
Topological domaini105 – 118CytoplasmicSequence analysisAdd BLAST14
Transmembranei119 – 139HelicalSequence analysisAdd BLAST21
Topological domaini140ExtracellularSequence analysis1
Transmembranei141 – 161HelicalSequence analysisAdd BLAST21
Topological domaini162 – 168CytoplasmicSequence analysis7
Transmembranei169 – 189HelicalSequence analysisAdd BLAST21
Topological domaini190 – 200ExtracellularSequence analysisAdd BLAST11
Transmembranei201 – 221HelicalSequence analysisAdd BLAST21
Topological domaini222 – 356CytoplasmicSequence analysisAdd BLAST135
Transmembranei357 – 377HelicalSequence analysisAdd BLAST21
Topological domaini378 – 384ExtracellularSequence analysis7
Transmembranei385 – 405HelicalSequence analysisAdd BLAST21
Topological domaini406 – 413CytoplasmicSequence analysis8
Transmembranei414 – 434HelicalSequence analysisAdd BLAST21
Topological domaini435 – 440ExtracellularSequence analysis6
Transmembranei441 – 461HelicalSequence analysisAdd BLAST21
Topological domaini462 – 474CytoplasmicSequence analysisAdd BLAST13
Transmembranei475 – 497HelicalSequence analysisAdd BLAST23
Topological domaini498 – 506ExtracellularSequence analysis9
Transmembranei507 – 527HelicalSequence analysisAdd BLAST21
Topological domaini528 – 555CytoplasmicSequence analysisAdd BLAST28

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002522741 – 555Probable metabolite transport protein YDR387CAdd BLAST555

Proteomic databases

PRIDEiQ04162.

PTM databases

iPTMnetiQ04162.

Interactioni

Protein-protein interaction databases

BioGridi32448. 4 interactors.
DIPiDIP-4084N.
MINTiMINT-478807.

Structurei

3D structure databases

ProteinModelPortaliQ04162.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi315 – 318Poly-Ser4

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00850000132274.
HOGENOMiHOG000202868.
InParanoidiQ04162.
OrthoDBiEOG092C305R.

Family and domain databases

CDDicd06174. MFS. 2 hits.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q04162-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTDESEDVY SDLYSIISQV TSNTANDIEQ LPYALTFKTS LIFVGATIGG
60 70 80 90 100
LLFGYDTGVI SGVLLSLKPE DLSLVVLTDV QKELITSSTS VGSFFGSILA
110 120 130 140 150
FPLADRYGRR ITLAICCSIF ILAAIGMAIA RTLTFLICGR LLVGIAVGVS
160 170 180 190 200
AQCVPLFLSE ISPSRIRGFM LTLNIIAITG GQLVSYVIAS LMKEIDNSWR
210 220 230 240 250
YLFALSAIPA ILFLSILDFI PESPRWSISK GDILYTRDSL RMLYPTASTY
260 270 280 290 300
HVNSKIKQLI IELDKLRLYE DASEPLLVQS QSVIRYMDSS TSGTLSPPNI
310 320 330 340 350
KRLSSNTERT SNTMSSSSAY LSALRGPAPN GALASNKKKR HRMEPRTIRA
360 370 380 390 400
LIVGCMLMFF QQITGFNAFM YYAAIIFSKF NIKNPLLPPI LIASTNFIFT
410 420 430 440 450
FFAMYTMDSL GRRAILLRTI LIMTVGLLLC SVGFGHDQVN LLLISVVIYV
460 470 480 490 500
AAYASAMGSV PWTCVEFLPL NRRSFGASCI ACTNWLTNAF VSMTYLSTIN
510 520 530 540 550
TIGDENTMLI FAFFTVCAWF FVYFWYPEVK GLSLEEVGRV FDNGIDVHYV

FRTYH
Length:555
Mass (Da):61,509
Last modified:November 1, 1996 - v1
Checksum:iD1EF726664D3A494
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U32274 Genomic DNA. Translation: AAB64829.1.
BK006938 Genomic DNA. Translation: DAA12231.1.
PIRiS69671.
RefSeqiNP_010675.3. NM_001180695.3.

Genome annotation databases

EnsemblFungiiYDR387C; YDR387C; YDR387C.
GeneIDi851995.
KEGGisce:YDR387C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U32274 Genomic DNA. Translation: AAB64829.1.
BK006938 Genomic DNA. Translation: DAA12231.1.
PIRiS69671.
RefSeqiNP_010675.3. NM_001180695.3.

3D structure databases

ProteinModelPortaliQ04162.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32448. 4 interactors.
DIPiDIP-4084N.
MINTiMINT-478807.

Protein family/group databases

TCDBi2.A.1.1.101. the major facilitator superfamily (mfs).

PTM databases

iPTMnetiQ04162.

Proteomic databases

PRIDEiQ04162.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR387C; YDR387C; YDR387C.
GeneIDi851995.
KEGGisce:YDR387C.

Organism-specific databases

EuPathDBiFungiDB:YDR387C.
SGDiS000002795. YDR387C.

Phylogenomic databases

GeneTreeiENSGT00850000132274.
HOGENOMiHOG000202868.
InParanoidiQ04162.
OrthoDBiEOG092C305R.

Enzyme and pathway databases

BioCyciYEAST:G3O-29935-MONOMER.
ReactomeiR-SCE-428790. Facilitative Na+-independent glucose transporters.
R-SCE-429593. Inositol transporters.
R-SCE-8856825. Cargo recognition for clathrin-mediated endocytosis.

Miscellaneous databases

PROiQ04162.

Family and domain databases

CDDicd06174. MFS. 2 hits.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYD387_YEAST
AccessioniPrimary (citable) accession number: Q04162
Secondary accession number(s): D6VT21
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.