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Protein

Probable metabolite transport protein YDR387C

Gene

YDR387C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • glucose import Source: GO_Central
  • hexose transmembrane transport Source: GO_Central
  • transmembrane transport Source: SGD
  • transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29935-MONOMER.
ReactomeiR-SCE-428790. Facilitative Na+-independent glucose transporters.
R-SCE-429593. Inositol transporters.

Protein family/group databases

TCDBi2.A.1.1.101. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Probable metabolite transport protein YDR387C
Gene namesi
Ordered Locus Names:YDR387C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR387C.
SGDiS000002795. YDR387C.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3939CytoplasmicSequence analysisAdd
BLAST
Transmembranei40 – 6021HelicalSequence analysisAdd
BLAST
Topological domaini61 – 8323ExtracellularSequence analysisAdd
BLAST
Transmembranei84 – 10421HelicalSequence analysisAdd
BLAST
Topological domaini105 – 11814CytoplasmicSequence analysisAdd
BLAST
Transmembranei119 – 13921HelicalSequence analysisAdd
BLAST
Topological domaini140 – 1401ExtracellularSequence analysis
Transmembranei141 – 16121HelicalSequence analysisAdd
BLAST
Topological domaini162 – 1687CytoplasmicSequence analysis
Transmembranei169 – 18921HelicalSequence analysisAdd
BLAST
Topological domaini190 – 20011ExtracellularSequence analysisAdd
BLAST
Transmembranei201 – 22121HelicalSequence analysisAdd
BLAST
Topological domaini222 – 356135CytoplasmicSequence analysisAdd
BLAST
Transmembranei357 – 37721HelicalSequence analysisAdd
BLAST
Topological domaini378 – 3847ExtracellularSequence analysis
Transmembranei385 – 40521HelicalSequence analysisAdd
BLAST
Topological domaini406 – 4138CytoplasmicSequence analysis
Transmembranei414 – 43421HelicalSequence analysisAdd
BLAST
Topological domaini435 – 4406ExtracellularSequence analysis
Transmembranei441 – 46121HelicalSequence analysisAdd
BLAST
Topological domaini462 – 47413CytoplasmicSequence analysisAdd
BLAST
Transmembranei475 – 49723HelicalSequence analysisAdd
BLAST
Topological domaini498 – 5069ExtracellularSequence analysis
Transmembranei507 – 52721HelicalSequence analysisAdd
BLAST
Topological domaini528 – 55528CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 555555Probable metabolite transport protein YDR387CPRO_0000252274Add
BLAST

PTM databases

iPTMnetiQ04162.

Interactioni

Protein-protein interaction databases

BioGridi32448. 4 interactions.
DIPiDIP-4084N.
MINTiMINT-478807.

Structurei

3D structure databases

ProteinModelPortaliQ04162.
SMRiQ04162. Positions 36-545.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi315 – 3184Poly-Ser

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00590000083062.
HOGENOMiHOG000202868.
InParanoidiQ04162.
OrthoDBiEOG7QG4D1.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q04162-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTDESEDVY SDLYSIISQV TSNTANDIEQ LPYALTFKTS LIFVGATIGG
60 70 80 90 100
LLFGYDTGVI SGVLLSLKPE DLSLVVLTDV QKELITSSTS VGSFFGSILA
110 120 130 140 150
FPLADRYGRR ITLAICCSIF ILAAIGMAIA RTLTFLICGR LLVGIAVGVS
160 170 180 190 200
AQCVPLFLSE ISPSRIRGFM LTLNIIAITG GQLVSYVIAS LMKEIDNSWR
210 220 230 240 250
YLFALSAIPA ILFLSILDFI PESPRWSISK GDILYTRDSL RMLYPTASTY
260 270 280 290 300
HVNSKIKQLI IELDKLRLYE DASEPLLVQS QSVIRYMDSS TSGTLSPPNI
310 320 330 340 350
KRLSSNTERT SNTMSSSSAY LSALRGPAPN GALASNKKKR HRMEPRTIRA
360 370 380 390 400
LIVGCMLMFF QQITGFNAFM YYAAIIFSKF NIKNPLLPPI LIASTNFIFT
410 420 430 440 450
FFAMYTMDSL GRRAILLRTI LIMTVGLLLC SVGFGHDQVN LLLISVVIYV
460 470 480 490 500
AAYASAMGSV PWTCVEFLPL NRRSFGASCI ACTNWLTNAF VSMTYLSTIN
510 520 530 540 550
TIGDENTMLI FAFFTVCAWF FVYFWYPEVK GLSLEEVGRV FDNGIDVHYV

FRTYH
Length:555
Mass (Da):61,509
Last modified:November 1, 1996 - v1
Checksum:iD1EF726664D3A494
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U32274 Genomic DNA. Translation: AAB64829.1.
BK006938 Genomic DNA. Translation: DAA12231.1.
PIRiS69671.
RefSeqiNP_010675.3. NM_001180695.3.

Genome annotation databases

EnsemblFungiiYDR387C; YDR387C; YDR387C.
GeneIDi851995.
KEGGisce:YDR387C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U32274 Genomic DNA. Translation: AAB64829.1.
BK006938 Genomic DNA. Translation: DAA12231.1.
PIRiS69671.
RefSeqiNP_010675.3. NM_001180695.3.

3D structure databases

ProteinModelPortaliQ04162.
SMRiQ04162. Positions 36-545.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32448. 4 interactions.
DIPiDIP-4084N.
MINTiMINT-478807.

Protein family/group databases

TCDBi2.A.1.1.101. the major facilitator superfamily (mfs).

PTM databases

iPTMnetiQ04162.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR387C; YDR387C; YDR387C.
GeneIDi851995.
KEGGisce:YDR387C.

Organism-specific databases

EuPathDBiFungiDB:YDR387C.
SGDiS000002795. YDR387C.

Phylogenomic databases

GeneTreeiENSGT00590000083062.
HOGENOMiHOG000202868.
InParanoidiQ04162.
OrthoDBiEOG7QG4D1.

Enzyme and pathway databases

BioCyciYEAST:G3O-29935-MONOMER.
ReactomeiR-SCE-428790. Facilitative Na+-independent glucose transporters.
R-SCE-429593. Inositol transporters.

Miscellaneous databases

PROiQ04162.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
    Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
    , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
    Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiYD387_YEAST
AccessioniPrimary (citable) accession number: Q04162
Secondary accession number(s): D6VT21
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.