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Protein

Transcriptional activator ARO80

Gene

ARO80

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcription activator required for the expression of genes involved in the catabolism of aromatic amino acids such as the aromatic aminotransferase II ARO9 and the phenylpyruvate decarboxylase ARO10.

Miscellaneous

Present with 319 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi25 – 58Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST34

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processBranched-chain amino acid catabolism, Phenylalanine catabolism, Transcription, Transcription regulation, Tryptophan catabolism, Tyrosine catabolism
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-29962-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional activator ARO80
Gene namesi
Name:ARO80
Ordered Locus Names:YDR421W
ORF Names:D9461.10
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR421W
SGDiS000002829 ARO80

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001149381 – 950Transcriptional activator ARO80Add BLAST950

Proteomic databases

MaxQBiQ04052
PaxDbiQ04052
PRIDEiQ04052

PTM databases

iPTMnetiQ04052

Interactioni

Protein-protein interaction databases

BioGridi32480, 58 interactors
DIPiDIP-1012N
IntActiQ04052, 2 interactors
MINTiQ04052
STRINGi4932.YDR421W

Structurei

3D structure databases

ProteinModelPortaliQ04052
SMRiQ04052
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi921 – 943Asn-richAdd BLAST23

Phylogenomic databases

HOGENOMiHOG000034058
InParanoidiQ04052
OMAiVRVYTHS
OrthoDBiEOG092C0KB3

Family and domain databases

CDDicd00067 GAL4, 1 hit
Gene3Di4.10.240.10, 1 hit
InterProiView protein in InterPro
IPR001138 Zn2-C6_fun-type_DNA-bd
IPR036864 Zn2-C6_fun-type_DNA-bd_sf
PfamiView protein in Pfam
PF00172 Zn_clus, 1 hit
SMARTiView protein in SMART
SM00066 GAL4, 1 hit
SUPFAMiSSF57701 SSF57701, 1 hit
PROSITEiView protein in PROSITE
PS00463 ZN2_CY6_FUNGAL_1, 1 hit
PS50048 ZN2_CY6_FUNGAL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q04052-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAKKRPSGN AAFELPKRRR TYQACISCRS RKVKCDLGPV DNPHDPPCAR
60 70 80 90 100
CKRELKKCIF SSNKGTSNDL PPNSINAISL PSLGKSKQEI QNDSTSPILS
110 120 130 140 150
DVPLSRKGIS SEKSFKSEGM KWKLELSSMQ NALEFLAQAA GTVAKEGAKE
160 170 180 190 200
IIKEKSTTPK PLKSSLDATN KSATDEGLKR LSKSDSTNTL YENTADMLNH
210 220 230 240 250
TLNTNRKTSQ LMEEIGKVRP PPTRKIDDFD YIGPDSLLTK EEAIELIEAF
260 270 280 290 300
FLTMHPFFPN IPLQLHDPKE LAEYPILFCA ILTVSARYHP FDTLGLDNGE
310 320 330 340 350
DGMRHIEVHD KLWVYCQKLI SQTIWAEAST RSIGTVLAFI IFTEWNPRSI
360 370 380 390 400
HYKWSDYAND PELNNVNARG SKNISTRKDE EGLTGVGAIR RSDRMSWMLT
410 420 430 440 450
GSAVRLAQDM GFIENSSKVF IVTHISETTS AMNMNQRSLL AESFSVLNLN
460 470 480 490 500
LGKIENDGNE SNEDYLGNEK FYLNEILPDE ESKLRWKRVF ENSENDHDNE
510 520 530 540 550
KNFLTDWERE FLNDEYVLYY SNKKDDTNLA QNHIPPFPLR FSFAQRAKIE
560 570 580 590 600
IIRILSIAYE TIYCEKNKRK LATTDQRHNL SVLSVFSPLI EGWLSNYREL
610 620 630 640 650
LVPLSDVPFS LADRKNKKQI FDNIDRINGE SIITDFNYCQ LYIFSLALQV
660 670 680 690 700
DGKTSRLNMN EIVTSARYVE LAYRSAKEIL SSAKRVSRQG MLKYMPVRWV
710 720 730 740 750
IRIIRSIAFI VKCYLTLTGS ELATNPDARN ILKLSAISVD ETFDIIRDTA
760 770 780 790 800
VTLKEATPDE LHLCQRYAAI LMYLCTEMKL RKKSYLERPP LLRDGTTPLE
810 820 830 840 850
SNRESSLEGQ DLTKKPIFSK RIGYNKTETT FEPSERPLTE EINSNSQNSN
860 870 880 890 900
DTSSKGIVDP FVEQNNDITT ALLNNELFQG PSLSDEVTDW FGASEDIGLE
910 920 930 940 950
FVEPWTELIE QRYMQCGDGD NNNFENLYNL FVNSNNINND INNSRPITRK
Length:950
Mass (Da):108,205
Last modified:November 1, 1996 - v1
Checksum:i3F86083C127D32A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33007 Genomic DNA Translation: AAB64863.1
BK006938 Genomic DNA Translation: DAA12261.1
PIRiS69704
RefSeqiNP_010709.1, NM_001180729.1

Genome annotation databases

EnsemblFungiiYDR421W; YDR421W; YDR421W
GeneIDi852031
KEGGisce:YDR421W

Similar proteinsi

Entry informationi

Entry nameiARO80_YEAST
AccessioniPrimary (citable) accession number: Q04052
Secondary accession number(s): D6VT51
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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