Q03Y12 (Q03Y12_LEUMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase EMBL ABJ61910.1

Gene names

Ordered Locus Names:

LEUM_0801

Organism

Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523) [Complete proteome] [HAMAP]

Taxonomic identifier

203120 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Leuconostoc

Protein attributes

Sequence length	283 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. SAAS SAAS006269
Pathway	Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. SAAS SAAS006269 Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. SAAS SAAS006269
Subcellular location	Cytoplasm By similarity SAAS SAAS006269.

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis SAAS SAAS006269
Cellular component	Cytoplasm SAAS SAAS006269
Molecular function	Transferase SAAS SAAS006269
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-deoxy-8-phosphooctulonate synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q03Y12 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 90AEA9D661E54610	FASTA	283	31,491
	10 20 30 40 50 60 MTKISEVFQE YNFSDDKLTL LAGPCAIESY ETCAEVAEKL KEITDELGIN FVFKSSFDKA 70 80 90 100 110 120 NRSSLDSDRG AGMAHGLEIL KKIKETYNVP IVTDVHESYQ CEPVAKVADV LQIPAYLSRQ 130 140 150 160 170 180 TDLLIAAGKT GRVVNIKKAQ FMAPEDIQSA VHKVEETNKH ILVTERGSMF GYHQLVVDMT 190 200 210 220 230 240 SLIQMRETNF PIIYDATHSI QIPSGYGNHS GGNRDYAFPL MRAALTIGVA GIFAEVHPNP 250 260 270 280 PKAISDQDSQ LYLSKIRPIL EVANDLFHQN LKMKAVYDHE GLL

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000414 Genomic DNA. Translation: ABJ61910.1.
RefSeq	YP_818283.1. NC_008531.1.
3D structure databases
ProteinModelPortal	Q03Y12.
SMR	Q03Y12. Positions 16-261.
ModBase	Search...
Protein-protein interaction databases
STRING	Q03Y12.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4423927.
GenomeReviews	Gene locus LEUM_0801 in contig CP000414_GR.
KEGG	lme:LEUM_0801.
NMPDR	fig|203120.1.peg.1613.
PATRIC	22409589. VBILeuMes50664_0796.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2877.
HOGENOM	HBG575990.
OMA	HEPHQAA.
PhylomeDB	Q03Y12.
ProtClustDB	PRK05198.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006269. KDO8P_synthase. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01627.
PANTHER	PTHR21057:SF2. KDO8P_synthase. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR01362. KDO8P_synth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q03Y12_LEUMM

Accession

Primary (citable) accession number: Q03Y12

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)