Q03WP5 (Q03WP5_LEUMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase 2 HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase 2 HAMAP MF_00020

Gene names

Name:	ackA2 HAMAP MF_00020
Ordered Locus Names:	LEUM_1280

Organism

Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523) [Complete proteome] [HAMAP]

Taxonomic identifier

203120 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Leuconostoc

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 SAAS SAAS000890 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020 SAAS SAAS000890
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. HAMAP MF_00020 RuleBase RU003835

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00020 SAAS SAAS000890
Ligand	ATP-binding HAMAP MF_00020 SAAS SAAS000890 Nucleotide-binding
Molecular function	Kinase SAAS SAAS000890 HAMAP MF_00020 RuleBase RU003835 EMBL ABJ62377.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q03WP5 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: C861820603CDFEA2	FASTA	418	45,770
	10 20 30 40 50 60 MSKIMAVNAG SSSLKFQLLE MPEETVITQG VIERIGMDDA IITVKYGADV EPVRLVGTED 70 80 90 100 110 120 GTISSTKSGD QKYEAELPIK DHHAAIDLML KKLSDLGIIK DFQEITGVGH RVVAGGEWFN 130 140 150 160 170 180 HSVVVDDDVL SKIDRLADYA PLHNPANAMG IRAFQKLLPH ATSVAVFDTS FHQTMPEKNY 190 200 210 220 230 240 LYSLPYEYYA RYGARKYGAH GTSHRYVTER AADKLGIPLD EFNAISFHLG AGASVTAIKN 250 260 270 280 290 300 GKSYDTSMGF TPLAGLTMAT RSGDVDPSLI YYIQEREGLS NEEMLNVLNK KSGLLGISTI 310 320 330 340 350 360 SSDMRDLENV QETNTHAQLA LDMFYDRVIR YAGQYFAELG RVDAIIFTAG IGENDAVTRA 370 380 390 400 410 KVLKSLAFAG VDLDEEANNV RGKETIITTS GSKVTGLLIP TNEELMIARD VVTLQNTK

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000414 Genomic DNA. Translation: ABJ62377.1.
RefSeq	YP_818750.1. NC_008531.1.
3D structure databases
ProteinModelPortal	Q03WP5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q03WP5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4423028.
GenomeReviews	Gene locus LEUM_1280 in contig CP000414_GR.
KEGG	lme:LEUM_1280.
NMPDR	fig|203120.1.peg.376.
PATRIC	22410545. VBILeuMes50664_1275.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	MIAREVV.
PhylomeDB	Q03WP5.
ProtClustDB	CLSK778436.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 2 hits. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q03WP5_LEUMM

Accession

Primary (citable) accession number: Q03WP5

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)