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Protein
Submitted name:

tRNA and rRNA cytosine-C5-methylase

Gene

LEUM_1513

Organism
Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei287S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei315S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei333S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei386NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
tRNA and rRNA cytosine-C5-methylaseImported
Gene namesi
Ordered Locus Names:LEUM_1513Imported
OrganismiLeuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523)Imported
Taxonomic identifieri203120 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
Proteomesi
  • UP000000362 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi203120.LEUM_1513.

Structurei

3D structure databases

ProteinModelPortaliQ03W17.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini173 – 447SAM_MT_RSMB_NOPInterPro annotationAdd BLAST275

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.
OrthoDBiPOG091H02E2.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR031341. Methyltr_RsmF_N.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF17125. Methyltr_RsmF_N. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q03W17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDKRVYSDN PRVLAVQTLA KIKNGAYSNL QLNQVIKQHK LGEADTRLLT
60 70 80 90 100
TLVYGVIQHR LTFEYWLEPF VGSKKIDPWV RELLYTAIFQ MEYLDKIPQH
110 120 130 140 150
AIFNESIEVA KILGHVGTGK FVTAILHNIS RKGLRSVADI GDDIQRLSIE
160 170 180 190 200
ASLPVWLVEE LIKQNGDERA RQIIATINDA PKQSIRVNTL LATDQEVVTA
210 220 230 240 250
LESENFTITA SSVAAHAFLV SGGHVASSKA YHDGWLTLQD ESAMLPVESL
260 270 280 290 300
HLTPEVKSIL DAAAAPGGKT TQLAQYSAPD AVITALDVHE HKIKLINNNA
310 320 330 340 350
ERLHVADKIH ARVLDARKVP EQIDKKFDRI LVDAPCSGFG LLRRKPEIRY
360 370 380 390 400
DKTLEDVESL ARLQTQILDS VSQNLAKNGI MVYSTCTILR QENDDVVTNF
410 420 430 440
LEDHPNFELI PTETTYKLKL DHGEKALHVY PDDYHTDGFF VATLRKND
Length:448
Mass (Da):50,210
Last modified:November 14, 2006 - v1
Checksum:iA5B09EBFB31A50FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000414 Genomic DNA. Translation: ABJ62605.1.
RefSeqiWP_011680185.1. NC_008531.1.

Genome annotation databases

EnsemblBacteriaiABJ62605; ABJ62605; LEUM_1513.
GeneIDi29577423.
KEGGilme:LEUM_1513.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ03W17_LEUMM
AccessioniPrimary (citable) accession number: Q03W17
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: June 7, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported