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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciLMES203120:GJ8T-1694-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:LEUM_1694
OrganismiLeuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523)
Taxonomic identifieri203120 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
ProteomesiUP000000362 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 504504Phosphoenolpyruvate carboxylasePRO_0000309596Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi203120.LEUM_1694.

Structurei

3D structure databases

ProteinModelPortaliQ03VI7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1892.
HOGENOMiHOG000038601.
KOiK01595.
OMAiQSSFKYD.
OrthoDBiEOG6WDSG0.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

Q03VI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSRKIPSIM GTQHPDNANA PFWESSQQPF ISAYRETGEA FENFNELNVD
60 70 80 90 100
EYMWDWEGKH ADAAVIDRLF STEYDYFKDH QIGRDKFLTF RFPNIWEEKG
110 120 130 140 150
YNLMQAMTAF LSSEDFAHDL GFSRPLFEAI LPMAQRADQI LKMQVLFEKL
160 170 180 190 200
ANFKSAEFTR SDKNTPYIEM IPLFEDFETQ LHAPEILKEY LNLHEEHFGF
210 220 230 240 250
RPKYMRVFLA GSDSALTAGF MSSITGNKLA IARLHEFAEE ENIEIFPISG
260 270 280 290 300
TGSAIFRGGL SPHRIDRYVT EFPGVRTATV QSAFRYDFPI EEVQKGIAEL
310 320 330 340 350
KEKLPVAEPL KISLDDQKIL TEIAEESAKF YSNTLDNLVP SMQAIFKAFP
360 370 380 390 400
KRRDRRQHVG VLGYSRSVDG IELPRAINFT GSFYSVGVPP EFIGFGRALK
410 420 430 440 450
HLDADHLSVF VRSYPSMSKD FNELARFVNM DALQILKTQN SAWAEVEEDI
460 470 480 490 500
LIMQRIFKFE IGPQTREEQQ HAEIALQVVQ FKDGAPVAIT ALINRMAQLR

HFLG
Length:504
Mass (Da):57,799
Last modified:November 14, 2006 - v1
Checksum:iCB5A60F2A4B3F033
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000414 Genomic DNA. Translation: ABJ62785.1.
RefSeqiWP_011680311.1. NC_008531.1.
YP_819158.1. NC_008531.1.

Genome annotation databases

EnsemblBacteriaiABJ62785; ABJ62785; LEUM_1694.
KEGGilme:LEUM_1694.
PATRICi22411353. VBILeuMes50664_1674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000414 Genomic DNA. Translation: ABJ62785.1.
RefSeqiWP_011680311.1. NC_008531.1.
YP_819158.1. NC_008531.1.

3D structure databases

ProteinModelPortaliQ03VI7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203120.LEUM_1694.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ62785; ABJ62785; LEUM_1694.
KEGGilme:LEUM_1694.
PATRICi22411353. VBILeuMes50664_1674.

Phylogenomic databases

eggNOGiCOG1892.
HOGENOMiHOG000038601.
KOiK01595.
OMAiQSSFKYD.
OrthoDBiEOG6WDSG0.

Enzyme and pathway databases

BioCyciLMES203120:GJ8T-1694-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 8293 / NCDO 523.

Entry informationi

Entry nameiCAPPA_LEUMM
AccessioniPrimary (citable) accession number: Q03VI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: November 14, 2006
Last modified: April 1, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.