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Q03UX8 (PGK_LEUMM) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:LEUM_1921
OrganismLeuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523) [Complete proteome] [HAMAP]
Taxonomic identifier203120 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000009627

Regions

Nucleotide binding361 – 3644ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1191Substrate By similarity
Binding site1611Substrate By similarity
Binding site2121ATP By similarity
Binding site3011ATP; via carbonyl oxygen By similarity
Binding site3321ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q03UX8 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 8FC9906FF29E805E

FASTA40542,728
        10         20         30         40         50         60 
MAKLTVSDLE LSGKKVLMRV DFNVPIKAGV IGNDNRIVAA LPTIKYVLEN NGRAILFSHL 

        70         80         90        100        110        120 
GRIKSEDDKK ELSLAPVAAR LGELLGKDVK FVPQTRGEEL ESAINALQDG EVLMVENTRF 

       130        140        150        160        170        180 
EDVVDGEVVK NESKNNPELG KYWASLGDDL FINDAFGTAH RAHASNVGIA SNVSQAAAGF 

       190        200        210        220        230        240 
LMEKEIKFLG DAVANPVRPF VAIIGGAKVS DKIEIVKSLL NKADKVIVGG GMAYTFDAAK 

       250        260        270        280        290        300 
GNKIGNSLFE ADKVELAKEL MAEAGDKLVL PIDSIAADAF SNDAKTEVVD AEDGIPDGYM 

       310        320        330        340        350        360 
GLDIGPKSVK LLQDTLSDAK TVVWNGPMGV FEMSNFAKGT LAIGEELVKV TENGGTTIVG 

       370        380        390        400 
GGDSTAAVQQ LGVADKLTHI STGGGASLEY LEGKELPGIA SISEK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000414 Genomic DNA. Translation: ABJ62994.1.
RefSeqYP_819367.1. NC_008531.1.

3D structure databases

ProteinModelPortalQ03UX8.
SMRQ03UX8. Positions 2-405.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING203120.LEUM_1921.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ62994; ABJ62994; LEUM_1921.
GeneID4423652.
KEGGlme:LEUM_1921.
PATRIC22411803. VBILeuMes50664_1881.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAWEALDIG.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycLMES203120:GJ8T-1921-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_LEUMM
AccessionPrimary (citable) accession number: Q03UX8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: July 9, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways