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Q03UX8

- PGK_LEUMM

UniProt

Q03UX8 - PGK_LEUMM

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Protein
Phosphoglycerate kinase
Gene
pgk, LEUM_1921
Organism
Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei119 – 1191Substrate By similarity
Binding sitei161 – 1611Substrate By similarity
Binding sitei212 – 2121ATP By similarity
Binding sitei301 – 3011ATP; via carbonyl oxygen By similarity
Binding sitei332 – 3321ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi361 – 3644ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLMES203120:GJ8T-1921-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:LEUM_1921
OrganismiLeuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523)
Taxonomic identifieri203120 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
ProteomesiUP000000362: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 405405Phosphoglycerate kinaseUniRule annotation
PRO_1000009627Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi203120.LEUM_1921.

Structurei

3D structure databases

ProteinModelPortaliQ03UX8.
SMRiQ03UX8. Positions 2-405.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiWEALDIG.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q03UX8-1 [UniParc]FASTAAdd to Basket

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MAKLTVSDLE LSGKKVLMRV DFNVPIKAGV IGNDNRIVAA LPTIKYVLEN    50
NGRAILFSHL GRIKSEDDKK ELSLAPVAAR LGELLGKDVK FVPQTRGEEL 100
ESAINALQDG EVLMVENTRF EDVVDGEVVK NESKNNPELG KYWASLGDDL 150
FINDAFGTAH RAHASNVGIA SNVSQAAAGF LMEKEIKFLG DAVANPVRPF 200
VAIIGGAKVS DKIEIVKSLL NKADKVIVGG GMAYTFDAAK GNKIGNSLFE 250
ADKVELAKEL MAEAGDKLVL PIDSIAADAF SNDAKTEVVD AEDGIPDGYM 300
GLDIGPKSVK LLQDTLSDAK TVVWNGPMGV FEMSNFAKGT LAIGEELVKV 350
TENGGTTIVG GGDSTAAVQQ LGVADKLTHI STGGGASLEY LEGKELPGIA 400
SISEK 405
Length:405
Mass (Da):42,728
Last modified:November 14, 2006 - v1
Checksum:i8FC9906FF29E805E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000414 Genomic DNA. Translation: ABJ62994.1.
RefSeqiWP_011680468.1. NC_008531.1.
YP_819367.1. NC_008531.1.

Genome annotation databases

EnsemblBacteriaiABJ62994; ABJ62994; LEUM_1921.
GeneIDi4423652.
KEGGilme:LEUM_1921.
PATRICi22411803. VBILeuMes50664_1881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000414 Genomic DNA. Translation: ABJ62994.1 .
RefSeqi WP_011680468.1. NC_008531.1.
YP_819367.1. NC_008531.1.

3D structure databases

ProteinModelPortali Q03UX8.
SMRi Q03UX8. Positions 2-405.
ModBasei Search...

Protein-protein interaction databases

STRINGi 203120.LEUM_1921.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ62994 ; ABJ62994 ; LEUM_1921 .
GeneIDi 4423652.
KEGGi lme:LEUM_1921.
PATRICi 22411803. VBILeuMes50664_1881.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi WEALDIG.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci LMES203120:GJ8T-1921-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 8293 / NCDO 523.

Entry informationi

Entry nameiPGK_LEUMM
AccessioniPrimary (citable) accession number: Q03UX8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: September 3, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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