Q03UN6 (Q03UN6_LEUMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate 1-dehydrogenase RuleBase RU000497
EC=1.1.1.49 RuleBase RU000497

Gene names

Ordered Locus Names:

LEUM_2016

Organism

Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523) [Complete proteome] [HAMAP]

Taxonomic identifier

203120 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Leuconostoc

Protein attributes

Sequence length	486 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH. RuleBase RU000497
Pathway	Carbohydrate degradation; pentose phosphate pathway. RuleBase RU000497
Sequence similarities	Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism RuleBase RU000497
Ligand	NADP RuleBase RU000497
Molecular function	Oxidoreductase RuleBase RU000497 EMBL ABJ63086.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro glucose-6-phosphate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q03UN6 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: F0EA29B0AFAED40A	FASTA	486	54,575
	10 20 30 40 50 60 MVSEIKTLVT FFGGTGDLAK RKLYPSVFNL YKKGYLQEHF AIVGTARQQL SDDEFKQLVR 70 80 90 100 110 120 DSIKDFTEDQ AQAEAFIAHF SYRAHDVTDA ASYGILKSAI EEAATKFDID GNRIFYMSVA 130 140 150 160 170 180 PRFFGTIAKY LKSEGLLAET GYNRLMIEKP FGTSYATAEE LQSDLENAFD DDQLFRIDHY 190 200 210 220 230 240 LGKEMVQNIA ALRFGNPIFD AAWNKDYIKN VQVTLAEVLG VEERAGYYDT TGALLDMIQN 250 260 270 280 290 300 HTMQIVGWLA MEKPESFNDK DIRAAKNAAF NALKIYNEEE VNKYFVRAQY GAGDTADYKP 310 320 330 340 350 360 YLEEADVPAD SKNNTFIAGE LQFDLPRWEG VPFYVRSGKR LAAKQTRVDI VFKAGTFNFG 370 380 390 400 410 420 SEQEAQESVL SIIIDPKGAI ELKLNAKSVE DAFNTRTINL DWAVSDEDKK NTPEPYERMI 430 440 450 460 470 480 HDTMNGDGSN FADWNGVSIA WKFVDAITAV YDADKAPLET YKSGSMGPEA SDKLLAENGD AWVFKG

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000414 Genomic DNA. Translation: ABJ63086.1.
RefSeq	YP_819459.1. NC_008531.1.
3D structure databases
ProteinModelPortal	Q03UN6.
SMR	Q03UN6. Positions 2-486.
ModBase	Search...
Protein-protein interaction databases
STRING	Q03UN6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4423729.
GenomeReviews	Gene locus LEUM_2016 in contig CP000414_GR.
KEGG	lme:LEUM_2016.
NMPDR	fig|203120.1.peg.1158.
PATRIC	22411989. VBILeuMes50664_1972.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0364.
HOGENOM	HBG322449.
OMA	VGVDHNA.
PhylomeDB	Q03UN6.
ProtClustDB	CLSK778251.
Family and domain databases
InterPro	IPR001282. G6P_DH. IPR019796. G6P_DH_AS. IPR022675. G6P_DH_C. IPR022674. G6P_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00036.
PANTHER	PTHR23429. G6PDH. 1 hit.
Pfam	PF02781. G6PD_C. 1 hit. PF00479. G6PD_N. 1 hit. [Graphical view]
PIRSF	PIRSF000110. G6PD. 1 hit.
PRINTS	PR00079. G6PDHDRGNASE.
TIGRFAMs	TIGR00871. Zwf. 1 hit.
PROSITE	PS00069. G6P_DEHYDROGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q03UN6_LEUMM

Accession

Primary (citable) accession number: Q03UN6

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)