Q03SV6 (Q03SV6_LACBA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HAMAP-Rule MF_01039
Short name=BPG-dependent PGAM HAMAP-Rule MF_01039
Short name=PGAM HAMAP-Rule MF_01039
Short name=Phosphoglyceromutase HAMAP-Rule MF_01039
Short name=dPGM HAMAP-Rule MF_01039
EC=5.4.2.1 HAMAP-Rule MF_01039

Gene names

Name:	gpmA HAMAP-Rule MF_01039
Ordered Locus Names:	LVIS_0570 EMBL ABJ63716.1

Organism

Lactobacillus brevis (strain ATCC 367 / JCM 1170) [Complete proteome] [HAMAP] EMBL ABJ63716.1

Taxonomic identifier

387344 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus brevis

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP-Rule MF_01039 RuleBase RU004512
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP-Rule MF_01039 RuleBase RU004512 SAAS SAAS013078
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP-Rule MF_01039 RuleBase RU004512
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP-Rule MF_01039

Ontologies

Keywords
Biological process	Glycolysis HAMAP-Rule MF_01039 SAAS SAAS013078
Molecular function	Isomerase SAAS SAAS013078 HAMAP-Rule MF_01039 EMBL ABJ63716.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular_function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity HAMAP-Rule MF_01039
	Active site	177	1	By similarity HAMAP-Rule MF_01039
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity HAMAP-Rule MF_01039

Sequences

	Sequence		Length	Mass (Da)
	Q03SV6 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: CB1D854EB2C15B57	FASTA	223	25,282
	10 20 30 40 50 60 MATLVILRHG ESVANRDNIF TGWSDVPLTD RGREQAQAAG QLVAQTGIQF SALHTSMLQR 70 80 90 100 110 120 AIVTSHIVLA AIDQLYIPEY KSWRLNERHY GALRGKNKAA VQQQVGEQQV KIWRRSFSAV 130 140 150 160 170 180 PPLLDHVSQD RRYDAFGSHV EPRGESLEMA YHRLMPYWED QVAPRLLDGQ NQLIVAHGST 190 200 210 220 LRALIKYLDR VADADISQVE VANGEPIRYE FDSRLNVLDK QVL

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B., Mills D. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 367 / JCM 1170.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000416 Genomic DNA. Translation: ABJ63716.1.
RefSeq	YP_794747.1. NC_008497.1.
3D structure databases
ProteinModelPortal	Q03SV6.
ModBase	Search...
Protein-protein interaction databases
STRING	387344.LVIS_0570.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABJ63716; ABJ63716; LVIS_0570.
GeneID	4414244.
KEGG	lbr:LVIS_0570.
PATRIC	22200104. VBILacBre134470_0550.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0588.
HOGENOM	HOG000221682.
KO	K01834.
OMA	VYTGWND.
Enzyme and pathway databases
BioCyc	LBRE387344:GJ8S-570-MONOMER.
UniPathway	UPA00109; UER00186.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA.
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
PANTHER	PTHR11931. PTHR11931. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q03SV6_LACBA

Accession

Primary (citable) accession number: Q03SV6

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)