Q03S94 (Q03S94_LACBA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL ABJ63928.1
EC=1.5.1.3 EMBL ABJ63928.1

Gene names

Ordered Locus Names:

LVIS_0785

Organism

Lactobacillus brevis (strain ATCC 367 / JCM 1170) [Complete proteome] [HAMAP]

Taxonomic identifier

387344 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ABJ63928.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q03S94 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: BFD58673422AA86E	FASTA	163	18,385
	10 20 30 40 50 60 MLIFLWAESQ GRVIGLHGGL PWHLPADMHY FKTVTTGHTI VAGSKTFASF PRPLPNRKNI 70 80 90 100 110 120 VVSHQPATAF PENVSVLHSL PAVRAYAAAR PQEKIFVVGG AQLFAGLLDD VDFLYRTRID 130 140 150 160 AGFDGDTWMP VIDYSQFTLI DQQPGIRNEK NPYDFVFEQY QRH

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000416 Genomic DNA. Translation: ABJ63928.1.
RefSeq	YP_794959.1. NC_008497.1.
3D structure databases
ProteinModelPortal	Q03S94.
ModBase	Search...
Protein-protein interaction databases
STRING	Q03S94.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4414403.
GenomeReviews	Gene locus LVIS_0785 in contig CP000416_GR.
KEGG	lbr:LVIS_0785.
NMPDR	fig|387344.8.peg.746.
PATRIC	22200529. VBILacBre134470_0760.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0262.
HOGENOM	HBG665708.
OMA	QDEEGVI.
PhylomeDB	Q03S94.
ProtClustDB	CLSK581542.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q03S94_LACBA

Accession

Primary (citable) accession number: Q03S94

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)