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Q03QD4 (SYR_LACBA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:LVIS_1491
OrganismLactobacillus brevis (strain ATCC 367 / JCM 1170) [Complete proteome] [HAMAP]
Taxonomic identifier387344 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 563563Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018047

Regions

Motif122 – 13211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q03QD4 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 09D45BB5E7F39572

FASTA56362,843
        10         20         30         40         50         60 
MDYKQIVTAA LSDALAGQLT RDEIASKLER PKTSDKGDMA FPTFTLAKLL HQAPQQIAQD 

        70         80         90        100        110        120 
LAEKLDKTSF EKVEVVGPYL NFFFDKGAYS AETLQTVLTA GADYGQNDDG QGGNVPIDMS 

       130        140        150        160        170        180 
SPNIAKPMSM GHLRSTVIGN SIAEILTKNG YHPIKDNHLG DWGTQFGKLI TAYKLWGNEA 

       190        200        210        220        230        240 
DVKADPINKL VEYYVRFHKE DVDKPELDDT AREWFRKLEN GDEEAHELWQ WFRDASLQEF 

       250        260        270        280        290        300 
NDVYEKLGVT FDTFNGEAFY NDKLEEVVQI LKDKNLLVES QGAQVVDLSK YNLNPALILK 

       310        320        330        340        350        360 
SDGASLYITR DIATALYRDR TYHPAKNLYV VGSEQTYYFK QLKAVLQEMG VPSADDLEHI 

       370        380        390        400        410        420 
PFGLITVDGK KLSTRSGRII LLAKVLDDSV KLAAEEINEK NPDLANKDEV AQQVGVGAIV 

       430        440        450        460        470        480 
FGDLKNERTN NIDFVLADQL KFEGETGPYV QYSHARAESI LRKAGKVTIT TDGNQISDPE 

       490        500        510        520        530        540 
AWDTIKTLAD FPAMVKMACD EFEPSVIAKY AIRLAKTFNK YYAHSKILTE DAELPARLAL 

       550        560 
VKAVSTVLKE SLRLLGVQAP DEM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000416 Genomic DNA. Translation: ABJ64588.1.
RefSeqYP_795619.1. NC_008497.1.

3D structure databases

ProteinModelPortalQ03QD4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING387344.LVIS_1491.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ64588; ABJ64588; LVIS_1491.
GeneID4414057.
KEGGlbr:LVIS_1491.
PATRIC22201915. VBILacBre134470_1426.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247211.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycLBRE387344:GJ8S-1491-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_LACBA
AccessionPrimary (citable) accession number: Q03QD4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries