ID   Q03PD6_LEVBA            Unreviewed;       850 AA.
AC   Q03PD6;
DT   14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   14-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:ABJ64936.1};
GN   OrderedLocusNames=LVIS_1875 {ECO:0000313|EMBL:ABJ64936.1};
OS   Levilactobacillus brevis (strain ATCC 367 / BCRC 12310 / CIP 105137 / JCM
OS   1170 / LMG 11437 / NCIMB 947 / NCTC 947) (Lactobacillus brevis).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Levilactobacillus.
OX   NCBI_TaxID=387344 {ECO:0000313|EMBL:ABJ64936.1, ECO:0000313|Proteomes:UP000001652};
RN   [1] {ECO:0000313|EMBL:ABJ64936.1, ECO:0000313|Proteomes:UP000001652}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 367 / BCRC 12310 / CIP 105137 / JCM 1170 / LMG 11437 /
RC   NCIMB 947 / NCTC 947 {ECO:0000313|Proteomes:UP000001652};
RX   PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA   Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E.,
RA   Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA   Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA   Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA   Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA   Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA   Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R.,
RA   O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P.,
RA   Kozyavkin S., Weimer B., Mills D.;
RT   "Comparative genomics of the lactic acid bacteria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
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DR   EMBL; CP000416; ABJ64936.1; -; Genomic_DNA.
DR   RefSeq; WP_011668557.1; NC_008497.1.
DR   AlphaFoldDB; Q03PD6; -.
DR   STRING; 387344.LVIS_1875; -.
DR   KEGG; lbr:LVIS_1875; -.
DR   PATRIC; fig|387344.15.peg.1784; -.
DR   eggNOG; COG0515; Bacteria.
DR   HOGENOM; CLU_352948_0_0_9; -.
DR   Proteomes; UP000001652; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   PANTHER; PTHR24362:SF309; DAMAGE RESPONSE PROTEIN KINASE, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR24362; SERINE/THREONINE-PROTEIN KINASE NEK; 1.
DR   Pfam; PF05147; LANC_like; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF158745; LanC-like; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ABJ64936.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001652};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABJ64936.1};
KW   Transferase {ECO:0000313|EMBL:ABJ64936.1}.
FT   DOMAIN          208..491
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   850 AA;  96469 MW;  8AD01D8609AB106C CRC64;
     MSLELYGFTV RKLAKKFSEL GYRIDYDNNW IFFIKESTFN LSNQGWKIHV SSTATEFLES
     LDAVTSVVRK YDASFKIPRT WHAMLSLTTG AVPLVTTGKM ITIYPKQKSD IELETIVNEL
     YRTQNNKLFP PIFTDYQYKD SNIFLRYGSF IEQYVLDDKQ EPLLALFDES NVLIPDKRVF
     GAHTPSFVKV PRFITNYFPK RTTMQFPLTQ PRLLQRSAKG NIYKVLTPKG PALLKQGYNG
     SLAVRGNDTS ANRVLNEANI LHNIPDYVHK PRVLGISTTS DSVFMLESFM PGVSLENIFT
     SSVLIKTMLD TMIIKIAKNL MNQILEVHRA GVVIRDLSPS NVLVNEYGQV FLVDFEIGSF
     ITSPISFMGS TPGFFPSFLP LTTSRNSFCF DWYSFGAILF YLGTSIKPIF PESRSKLTKK
     AFFDKLYSIN ELTLNGHNCY SIACLGISIM ENFYEVNDNT ITTFFREALQ SSNEERSTKI
     SPAIFKISEI VSRTLSKKNT FSSEDIRRGP KEELLLLSLD KGMLGTLLLK ALYLDKNDNT
     NILSDFRRDI AFINRNIDDS NSINLVNGIS SLVYILSISK EFDKAQCHMY FNLQIKILNI
     IRRKVSHVVY NGVLYGLAGI GLSLFLAWDK DCDLFIKEQI KEINELISDL LLRRMITRDK
     RMHIGIKGVT REDSKVVSDF GFGEIGVASF LALINSSHNQ ELRTKAIKSS LENLYENRIV
     EGSSGIKVAQ TTGSLKYYPF LFSGISGILI FLELVRSHGC GVEVDESFRE QVFQSVIKNT
     YHNSPFLLNG DAGVLISLMI AKKDSVIEQK RLVALLLSES NLTSTGKRYW SLPGKFTLTK
     NFFLEGRFYN
//