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Q03LA9 (CAPP_STRTD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:STER_0760
OrganismStreptococcus thermophilus (strain ATCC BAA-491 / LMD-9) [Complete proteome] [HAMAP]
Taxonomic identifier322159 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length940 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 940940Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025598

Sites

Active site1381 By similarity
Active site6031 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q03LA9 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 369DE223D6E0E59A

FASTA940107,012
        10         20         30         40         50         60 
MAFNKLESSN NQEIISEEVG ILKELLDDAT RGIAGEQGLT TIQHLVELYD EGDYEALTQA 

        70         80         90        100        110        120 
ISEMTNDDMV VASRYFSLLP LLINISEDVD LAYEVNRKNN IDESYLGKLS ETFDVVAESD 

       130        140        150        160        170        180 
NARDILENVN VVPVLTAHPT QVQRKTMLEL TNHIHELLRK HRDVKDGLIN KDKWYADLRR 

       190        200        210        220        230        240 
YVEIMMKTDI IREKKLKVKN EITNVMEYYN SSLIKAITKL SHEFKRLAVE KGIELDNPTP 

       250        260        270        280        290        300 
ITMGMWIGGD RDGNPFVTAE TLKLSATLQS EVILNYYIEK VDNLYRSFSL SSRLTEVSET 

       310        320        330        340        350        360 
VAEMAKLSPD TSVYRENEPY RRAFSYIQSK LIQTLLFFKA GNFSNERAAK RLSENVRLGS 

       370        380        390        400        410        420 
VSTGEVVADF VHDRLSQSLQ AVSQQTTEFY ETAEAFHDDL LAIKNSLLEN DDSVLISGDF 

       430        440        450        460        470        480 
EELLQAVEVF GFYLATIDMR QDSSVHEACV AELLKSANIV DNYSELTEVE KVAVLLKELQ 

       490        500        510        520        530        540 
EDPRTLSSTN VSKSETLEKE LAIFRTARLL KDYLGEEVIK QHIISHTESV SDMFELAILL 

       550        560        570        580        590        600 
KEVGLVDTER ARVQIVPLFE TIEDLENSNE IMKQYLGYDI VKRWIKNSNN YQEIMLGYSD 

       610        620        630        640        650        660 
SNKDGGYLSS GWTLYKAQNE LTKIGEERGI KITFFHGRGG TVGRGGGPSY DAITSQPFGT 

       670        680        690        700        710        720 
IKDRIRLTEQ GEVIGNKYGN KDAAYYNLEM LVSATLDRMV TRQITDPDEL VDFREIMDSI 

       730        740        750        760        770        780 
VQDSNGIYRD LVFGNEHFYD YFFEASPIKE VSSLNIGSRP AARKTITDIS GLRAIPWVFS 

       790        800        810        820        830        840 
WSQNRIMLPG WYGVGSAFNH YIEAEEGNLE KLQHMFETWP FFRSLLSNVD MVLSKSDMNI 

       850        860        870        880        890        900 
AFHYAQLAES EEVRSVFNII LDEWQLTKNV ILAIEKHDDF LEESPSLKAS LGFRLPYFNV 

       910        920        930        940 
LNYIQIELIK RLRNNNLTDD EISLIHITIN GIATGLRNSG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000419 Genomic DNA. Translation: ABJ66013.1.
RefSeqYP_820209.1. NC_008532.1.

3D structure databases

ProteinModelPortalQ03LA9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING322159.STER_0760.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ66013; ABJ66013; STER_0760.
GeneID4438333.
KEGGste:STER_0760.
PATRIC19798783. VBIStrThe129203_0744.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMASILNCET.
OrthoDBEOG6TJ7T8.

Enzyme and pathway databases

BioCycSTHE322159:GJ9F-760-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 2 hits.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_STRTD
AccessionPrimary (citable) accession number: Q03LA9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families