Q03HL3 (GALT_PEDPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Galactose-1-phosphate uridylyltransferase
Short name=Gal-1-P uridylyltransferase
EC=2.7.7.12

Alternative name(s):
UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	PEPE_0208

Organism

Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) [Complete proteome] [HAMAP]

Taxonomic identifier

278197 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Pediococcus

Protein attributes

Sequence length	486 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 486	486	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_1000025026

Sequences

	Sequence		Length	Mass (Da)
	Q03HL3 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 2FC8D82865D0757E	FASTA	486	54,180
	10 20 30 40 50 60 MSSLEQFVQV VIDSPSPYTN LDRIYVHNRI LGLVGEDQPV EATDEQVTSL VDALVKTAVQ 70 80 90 100 110 120 NGKIEDAQSD RSILADQLMD LVTPLPSILN QRFWDKYQVS PKAATDYFFN LSKTNDYIKT 130 140 150 160 170 180 RAIAKNVSFP AETDFGELEI TINLSKPEKD PKAIAAARNQ PQDGYPLCQL CMQNEGYLGR 190 200 210 220 230 240 LGYPSRSNHR IIRMTLGGET WGFQYSPYAY FNEHSIFLDQ IHRPMVINRQ TFTNLLEIVK 250 260 270 280 290 300 QLPHYFVGSN ADLPIVGGSM LSHEHYQGGR HVFPMMKAPI ARTIDLGVAG VEAGIVKWPM 310 320 330 340 350 360 STIRLVGSDV VALTDAAVKI HDAWMNYSDE SVDVRAFTDG TRHHTTTPIA YKDGENYVLD 370 380 390 400 410 420 VVLRDNQTSA EFPDGIFHPH QDVQHIKKEN IGLIEVMGRA ILPARLKTEL VEVEKYLLGQ 430 440 450 460 470 480 TNQMAEMHQA WADQLKATNS ITAENVTAVV NAAVGNVFAR VLADAGVFKW DDAGEAAFAR FISAIN

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25745 / 183-1w.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000422 Genomic DNA. Translation: ABJ67309.1.
RefSeq	YP_803751.1. NC_008525.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q03HL3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4418617.
GenomeReviews	Gene locus PEPE_0208 in contig CP000422_GR.
KEGG	ppe:PEPE_0208.
NMPDR	fig|278197.10.peg.192.
PATRIC	22873774. VBIPedPen34213_0204.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4468.
HOGENOM	HBG337915.
OMA	TWGFQYS.
ProtClustDB	PRK05270.
Enzyme and pathway databases
BioCyc	PPEN278197:PEPE_0208-MONOMER.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR023425. GalP_uridyl_Trfase_II_CS. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
KO	K00965.
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. GalT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_PEDPA

Accession

Primary (citable) accession number: Q03HL3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 14, 2006
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program