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Protein

Uridine kinase

Gene

udk

Organism
Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + cytidine = ADP + CMP.UniRule annotationSAAS annotation
ATP + uridine = ADP + UMP.UniRule annotationSAAS annotation

Pathwayi: CTP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes CTP from cytidine.UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Uridine kinase (udk)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
This subpathway is part of the pathway CTP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CTP from cytidine, the pathway CTP biosynthesis via salvage pathway and in Pyrimidine metabolism.

Pathwayi: UMP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes UMP from uridine.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Uridine kinase (udk)
This subpathway is part of the pathway UMP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes UMP from uridine, the pathway UMP biosynthesis via salvage pathway and in Pyrimidine metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 21ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00574; UER00637
UPA00579; UER00640

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine kinaseUniRule annotationSAAS annotation (EC:2.7.1.48UniRule annotationSAAS annotation)
Alternative name(s):
Cytidine monophosphokinaseUniRule annotation
Uridine monophosphokinaseUniRule annotation
Gene namesi
Name:udkUniRule annotation
Ordered Locus Names:PEPE_0724Imported
OrganismiPediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)Imported
Taxonomic identifieri278197 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaePediococcus
Proteomesi
  • UP000000773 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi278197.PEPE_0724

Structurei

3D structure databases

ProteinModelPortaliQ03G87
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 194PRKInterPro annotationAdd BLAST186

Sequence similaritiesi

Belongs to the uridine kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DBI Bacteria
COG0572 LUCA
HOGENOMiHOG000262756
KOiK00876
OMAiTTLKPMH
OrthoDBiPOG091H04CS

Family and domain databases

CDDicd02023 UMPK, 1 hit
HAMAPiMF_00551 Uridine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR006083 PRK/URK
IPR000764 Uridine_kinase-like
IPR026008 Uridine_kinase_
PfamiView protein in Pfam
PF00485 PRK, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00235 udk, 1 hit

Sequencei

Sequence statusi: Complete.

Q03G87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTKNSPIII GVTGGSGSGK TTVSQKILEE LHGHSISIIQ QDSYYKDQAE
60 70 80 90 100
KTMEERRAVN YDHPLAFDAD LLYEHLKMLK NNQKIEVPIY DYKISTRSSE
110 120 130 140 150
VIEQDPTDVI ILEGILILAD ERIRDMLDIK VYVDTDDDIR IIRRIRRDME
160 170 180 190 200
QRARTLDSII NQYLTGVKPM YHQFIEPTKR YADVIVPEGG KNSVAIDLLV
210
TKVRDILSED GRDESFNK
Length:218
Mass (Da):25,028
Last modified:November 14, 2006 - v1
Checksum:i4D947357311A26BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000422 Genomic DNA Translation: ABJ67785.1
RefSeqiWP_002833824.1, NC_008525.1

Genome annotation databases

EnsemblBacteriaiABJ67785; ABJ67785; PEPE_0724
GeneIDi33061575
KEGGippe:PEPE_0724

Similar proteinsi

Entry informationi

Entry nameiQ03G87_PEDPA
AccessioniPrimary (citable) accession number: Q03G87
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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