Q03G87 (Q03G87_PEDPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Uridine kinase HAMAP-Rule MF_00551 RuleBase RU003825
EC=2.7.1.48 HAMAP-Rule MF_00551 RuleBase RU003825

Alternative name(s):
Cytidine monophosphokinase HAMAP-Rule MF_00551
Uridine monophosphokinase HAMAP-Rule MF_00551

Gene names

Name:	udk HAMAP-Rule MF_00551
Ordered Locus Names:	PEPE_0724

Organism

Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) [Complete proteome] [HAMAP] EMBL ABJ67785.1

Taxonomic identifier

278197 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Pediococcus › Pediococcus pentosaceus

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + cytidine = ADP + CMP. HAMAP-Rule MF_00551 RuleBase RU003825 ATP + uridine = ADP + UMP. HAMAP-Rule MF_00551 RuleBase RU003825
Pathway	Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3. HAMAP-Rule MF_00551 RuleBase RU003825 Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1. HAMAP-Rule MF_00551 RuleBase RU003825
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00551.
Sequence similarities	Belongs to the uridine kinase family. HAMAP-Rule MF_00551 RuleBase RU003824

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_00551
Ligand	ATP-binding SAAS SAAS000764 HAMAP-Rule MF_00551 RuleBase RU003528 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00551 SAAS SAAS000764 RuleBase RU003528 EMBL ABJ67785.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	CTP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway UMP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro uridine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	14 – 21	8	ATP By similarity HAMAP-Rule MF_00551

Sequences

	Sequence		Length	Mass (Da)
	Q03G87 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 4D947357311A26BF	FASTA	218	25,028
	10 20 30 40 50 60 MSTKNSPIII GVTGGSGSGK TTVSQKILEE LHGHSISIIQ QDSYYKDQAE KTMEERRAVN 70 80 90 100 110 120 YDHPLAFDAD LLYEHLKMLK NNQKIEVPIY DYKISTRSSE VIEQDPTDVI ILEGILILAD 130 140 150 160 170 180 ERIRDMLDIK VYVDTDDDIR IIRRIRRDME QRARTLDSII NQYLTGVKPM YHQFIEPTKR 190 200 210 YADVIVPEGG KNSVAIDLLV TKVRDILSED GRDESFNK

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B., Mills D. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25745 / 183-1w.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000422 Genomic DNA. Translation: ABJ67785.1.
RefSeq	YP_804227.1. NC_008525.1.
3D structure databases
ProteinModelPortal	Q03G87.
ModBase	Search...
Protein-protein interaction databases
STRING	278197.PEPE_0724.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABJ67785; ABJ67785; PEPE_0724.
GeneID	4418084.
KEGG	ppe:PEPE_0724.
PATRIC	22874804. VBIPedPen34213_0687.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0572.
HOGENOM	HOG000262756.
KO	K00876.
OMA	RKTVRPM.
Enzyme and pathway databases
BioCyc	PPEN278197:GI4Y-759-MONOMER.
UniPathway	UPA00574; UER00637. UPA00579; UER00640.
Family and domain databases
HAMAP	MF_00551. Uridine_kinase.
InterPro	IPR006083. PRK/URK. IPR000764. Uridine_kinase. [Graphical view]
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PRINTS	PR00988. URIDINKINASE.
TIGRFAMs	TIGR00235. udk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q03G87_PEDPA

Accession

Primary (citable) accession number: Q03G87

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)