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Protein

Uridine kinase

Gene

udk

Organism
Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + cytidine = ADP + CMP.UniRule annotationSAAS annotation
ATP + uridine = ADP + UMP.UniRule annotationSAAS annotation

Pathway:iCTP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes CTP from cytidine.UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Uridine kinase (udk)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
This subpathway is part of the pathway CTP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CTP from cytidine, the pathway CTP biosynthesis via salvage pathway and in Pyrimidine metabolism.

Pathway:iUMP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes UMP from uridine.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Uridine kinase (udk)
This subpathway is part of the pathway UMP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes UMP from uridine, the pathway UMP biosynthesis via salvage pathway and in Pyrimidine metabolism.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi14 – 218ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPPEN278197:GI4Y-724-MONOMER.
UniPathwayiUPA00574; UER00637.
UPA00579; UER00640.

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine kinaseUniRule annotation (EC:2.7.1.48UniRule annotation)
Alternative name(s):
Cytidine monophosphokinaseUniRule annotation
Uridine monophosphokinaseUniRule annotation
Gene namesi
Name:udkUniRule annotation
Ordered Locus Names:PEPE_0724Imported
OrganismiPediococcus pentosaceus (strain ATCC 25745 / 183-1w)Imported
Taxonomic identifieri278197 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaePediococcus
ProteomesiUP000000773 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi278197.PEPE_0724.

Structurei

3D structure databases

ProteinModelPortaliQ03G87.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uridine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0572.
HOGENOMiHOG000262756.
KOiK00876.
OMAiDIKIFVH.
OrthoDBiEOG6KMBCH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00551. Uridine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR000764. Uridine_kinase-like.
IPR026008. Uridine_kinase_.
[Graphical view]
PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PRINTSiPR00988. URIDINKINASE.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00235. udk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q03G87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTKNSPIII GVTGGSGSGK TTVSQKILEE LHGHSISIIQ QDSYYKDQAE
60 70 80 90 100
KTMEERRAVN YDHPLAFDAD LLYEHLKMLK NNQKIEVPIY DYKISTRSSE
110 120 130 140 150
VIEQDPTDVI ILEGILILAD ERIRDMLDIK VYVDTDDDIR IIRRIRRDME
160 170 180 190 200
QRARTLDSII NQYLTGVKPM YHQFIEPTKR YADVIVPEGG KNSVAIDLLV
210
TKVRDILSED GRDESFNK
Length:218
Mass (Da):25,028
Last modified:November 14, 2006 - v1
Checksum:i4D947357311A26BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000422 Genomic DNA. Translation: ABJ67785.1.
RefSeqiWP_002833824.1. NC_008525.1.

Genome annotation databases

EnsemblBacteriaiABJ67785; ABJ67785; PEPE_0724.
KEGGippe:PEPE_0724.
PATRICi22874804. VBIPedPen34213_0687.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000422 Genomic DNA. Translation: ABJ67785.1.
RefSeqiWP_002833824.1. NC_008525.1.

3D structure databases

ProteinModelPortaliQ03G87.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi278197.PEPE_0724.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ67785; ABJ67785; PEPE_0724.
KEGGippe:PEPE_0724.
PATRICi22874804. VBIPedPen34213_0687.

Phylogenomic databases

eggNOGiCOG0572.
HOGENOMiHOG000262756.
KOiK00876.
OMAiDIKIFVH.
OrthoDBiEOG6KMBCH.

Enzyme and pathway databases

UniPathwayiUPA00574; UER00637.
UPA00579; UER00640.
BioCyciPPEN278197:GI4Y-724-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00551. Uridine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR000764. Uridine_kinase-like.
IPR026008. Uridine_kinase_.
[Graphical view]
PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PRINTSiPR00988. URIDINKINASE.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00235. udk. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25745 / 183-1wImported.

Entry informationi

Entry nameiQ03G87_PEDPA
AccessioniPrimary (citable) accession number: Q03G87
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: July 22, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.