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Protein

UvrABC system protein C

Gene

uvrC

Organism
Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:PEPE_1135
OrganismiPediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)
Taxonomic identifieri278197 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaePediococcus
Proteomesi
  • UP000000773 Componenti: Chromosome

Subcellular locationi

Q03F33:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000778161 – 594UvrABC system protein CAdd BLAST594

Proteomic databases

PRIDEiQ03F33.

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi278197.PEPE_1135.

Structurei

3D structure databases

ProteinModelPortaliQ03F33.
SMRiQ03F33.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 92GIY-YIGUniRule annotationAdd BLAST78
Domaini197 – 232UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII. Bacteria.
COG0322. LUCA.
HOGENOMiHOG000279960.
KOiK03703.
OMAiLFPIRQC.
OrthoDBiPOG091H01BS.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q03F33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASEHIEHKL ALLPDKPGCY QMKNLNSQII YVGKAKNLKN RVRSYFKSSH
60 70 80 90 100
EGKTAKLVSE IADFDYIVTS SDKEAFLLEI TLIQKFQPYY NIKLKKGTGY
110 120 130 140 150
PYIKITNEKD PRMEIVSSVR RDGGFYFGPY PNVYAAEETL HFLEKVYPLR
160 170 180 190 200
RCNGFQGRPC LYYHMGQCLG ACFQEVPKEE YDQQIAKIKS FLRGNVAKIK
210 220 230 240 250
QSLQTKMQKA SEAMEFERAA DIRDQIHYIE VTVEKQKIIS NDSTPRDLFN
260 270 280 290 300
FYLDKGWLSI QIFFIRQSRL IKREKRLFPI ATDVNDELSS FILQFYNNKN
310 320 330 340 350
KVLPNEILVP SGLDNKIMAE ILGVPVRTPQ RGEKKNLLEL AKENAQITLE
360 370 380 390 400
EKFRLMELDE SKTTGAMKEI TDALGIPEGH RIEAFDHSHI QGSELVSAMV
410 420 430 440 450
VFTDGKPDKK MYRKFKLNTV DHADEAASTR EVIRRRYVRL LKEKQSLPDL
460 470 480 490 500
ILMDGGDIQL NAAKDVLVNE LSLHIPVAGM VKNDKHKTSD LIFGSQDQRV
510 520 530 540 550
QLDPKSQGFY LVQRIQDEVH RFAITFHRQL HAKNSLASQL DLIQGVGPKT
560 570 580 590
RNKLLKSFGS LNKIRDANLK EIEELGIPEK VAKTIKVSLS VHGK
Length:594
Mass (Da):68,086
Last modified:November 14, 2006 - v1
Checksum:i4F6759F057DDA93F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000422 Genomic DNA. Translation: ABJ68189.1.
RefSeqiWP_011673514.1. NC_008525.1.

Genome annotation databases

EnsemblBacteriaiABJ68189; ABJ68189; PEPE_1135.
GeneIDi33062477.
KEGGippe:PEPE_1135.

Similar proteinsi

Entry informationi

Entry nameiUVRC_PEDPA
AccessioniPrimary (citable) accession number: Q03F33
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 14, 2006
Last modified: October 25, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families