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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140GTPUniRule annotation1
Binding sitei144GTPUniRule annotation1
Binding sitei188GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 26GTPUniRule annotation5
Nucleotide bindingi109 – 111GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:PEPE_1183Imported
OrganismiPediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)Imported
Taxonomic identifieri278197 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaePediococcus
Proteomesi
  • UP000000773 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi278197.PEPE_1183

Structurei

3D structure databases

ProteinModelPortaliQ03EY5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 206TubulinInterPro annotationAdd BLAST193
Domaini208 – 325Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q03EY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFSMDESKS TGANIKVIGV GGGGGNAVNR MIAEGVKGVE FIVANTDVQA
60 70 80 90 100
LQASNADVKI QLGPKLTKGL GAGSTPDVGA KAAEESQQTI SSALEGADMI
110 120 130 140 150
FVTAGMGGGT GTGAAPMVAQ IAKEQGALTV GVVTRPFTFE GPKRARFAAE
160 170 180 190 200
GVANLKEHVD TLIIIANNRL LDLVDKKTPM MEAFNEADNV LRQGVQGISD
210 220 230 240 250
LITSPGYVNL DFADVKTVMQ NQGSALMGIG SASGENRTEE ATKKAISSPL
260 270 280 290 300
LETSIDGAEQ VLLNITGGPD LSLFEAQAAS QIVTEAANDD VNIIFGTSID
310 320 330 340 350
NDLQDGVRVT VIATGIDKKA GRASLHRQPA RTSFETPSSS VNTTTTNVSN
360 370 380 390 400
NTEIRGAGST ESLNTSSNSE QPTQAANDPF GDWQLRQSNA SNGVRPTSRD
410 420 430
NDSFRNVEKK EFNAFNDNNN ISSDDDSLDT PPFFKRRGK
Length:439
Mass (Da):46,019
Last modified:November 14, 2006 - v1
Checksum:i0D857946570D8C90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000422 Genomic DNA Translation: ABJ68237.1
RefSeqiWP_002833489.1, NC_008525.1

Genome annotation databases

EnsemblBacteriaiABJ68237; ABJ68237; PEPE_1183
GeneIDi33062182
KEGGippe:PEPE_1183

Similar proteinsi

Entry informationi

Entry nameiQ03EY5_PEDPA
AccessioniPrimary (citable) accession number: Q03EY5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health