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Protein

DNA helicase

Gene

PEPE_1372

Organism
Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent DNA helicase activity Source: InterPro
  3. DNA binding Source: InterPro

GO - Biological processi

  1. DNA unwinding involved in DNA replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HelicaseSAAS annotationImported, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPPEN278197:GI4Y-1372-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA helicaseSAAS annotation (EC:3.6.4.12SAAS annotation)
Gene namesi
Ordered Locus Names:PEPE_1372Imported
OrganismiPediococcus pentosaceus (strain ATCC 25745 / 183-1w)Imported
Taxonomic identifieri278197 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaePediococcus
ProteomesiUP000000773 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi278197.PEPE_1372.

Structurei

3D structure databases

ProteinModelPortaliQ03EG2.
SMRiQ03EG2. Positions 5-653.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0210.
HOGENOMiHOG000033016.
KOiK03657.
OMAiRLQIAFQ.
OrthoDBiEOG64N9TW.

Family and domain databases

Gene3Di1.10.10.160. 1 hit.
3.40.50.300. 4 hits.
InterProiIPR005751. ATP-dep_DNA_helicase_PcrA.
IPR013986. DExx_box_DNA_helicase_dom.
IPR014017. DNA_helicase_UvrD-like_C.
IPR000212. DNA_helicase_UvrD/REP.
IPR027417. P-loop_NTPase.
IPR014016. UvrD-like_ATP-bd.
[Graphical view]
PANTHERiPTHR11070. PTHR11070. 1 hit.
PfamiPF00580. UvrD-helicase. 1 hit.
PF13361. UvrD_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01073. pcrA. 1 hit.
PROSITEiPS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
PS51217. UVRD_HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q03EG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEINLIKGL NDMQKEAVQT TEGPLLIMAG AGSGKTRVLT HRVAYLIEEK
60 70 80 90 100
GVNPWNVLAI TFTNKAAREM RERVTSLLGD EAAEIWVSTF HALCVRILRR
110 120 130 140 150
NIDQLGYNRA FSIADPSEQR TLVKHILADL NYDPKKFDPR SVLGTISNAK
160 170 180 190 200
NDLKTPLTYR ENASTPYEQV VADIYEEYQR RLENNQALDF DDLIMKTIEL
210 220 230 240 250
FQKNPETLSF YQNKFHYIHV DEYQDTNQAQ YQLVTMLAKH FRNICVVGDS
260 270 280 290 300
DQSIYGWRGA DMQNIMNFES DYPDSKTVML EQNYRSTQNI LNAANDVIEN
310 320 330 340 350
NVERKPKQLW TDNDEGEKIS YYRGQTGIDE AHFIVQKIRE QIKEHNLNYG
360 370 380 390 400
DFAILYRTNA QSRVIEDTFV KSNIPYLMVG GHKFYDRKEI RDVLSYLTLI
410 420 430 440 450
ANEDDSMSFE RVINEPKRGI GSTSIAKLQA FADENNWSLL KAARSVQIAN
460 470 480 490 500
GISSRARNAI EDFAKMIDAL RKSGEFLNIT ELTEAVLEQT GYRAALEKSR
510 520 530 540 550
TMESEARLEN IDEFLTVTKQ FDDKNEAEGN EIADENGDNI QLVDFLADLA
560 570 580 590 600
LVSDQDNVEE EPSGVTLMTL HAAKGLEFPI VFLVGMEDGI FPLSRAMMDQ
610 620 630 640 650
EQLEEERRLA YVGITRARQK LYITNAYSRM LYGRTQTNPA SRFISEIGSQ
660 670 680 690 700
YLKSENEEKS FSRNTKEKSY PFDNNRNARA TASVYGNTHA TAVKSNGSGA
710 720 730 740 750
GKVSWNAGDK VEHKAWGIGT VVKVSGAGED AELDIAFKDQ GIKRLLAAFA

PIKRVVE
Length:757
Mass (Da):85,870
Last modified:November 14, 2006 - v1
Checksum:i43F716CEE180B3B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000422 Genomic DNA. Translation: ABJ68410.1.
RefSeqiYP_804852.1. NC_008525.1.

Genome annotation databases

EnsemblBacteriaiABJ68410; ABJ68410; PEPE_1372.
KEGGippe:PEPE_1372.
PATRICi22876056. VBIPedPen34213_1296.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000422 Genomic DNA. Translation: ABJ68410.1.
RefSeqiYP_804852.1. NC_008525.1.

3D structure databases

ProteinModelPortaliQ03EG2.
SMRiQ03EG2. Positions 5-653.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi278197.PEPE_1372.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ68410; ABJ68410; PEPE_1372.
KEGGippe:PEPE_1372.
PATRICi22876056. VBIPedPen34213_1296.

Phylogenomic databases

eggNOGiCOG0210.
HOGENOMiHOG000033016.
KOiK03657.
OMAiRLQIAFQ.
OrthoDBiEOG64N9TW.

Enzyme and pathway databases

BioCyciPPEN278197:GI4Y-1372-MONOMER.

Family and domain databases

Gene3Di1.10.10.160. 1 hit.
3.40.50.300. 4 hits.
InterProiIPR005751. ATP-dep_DNA_helicase_PcrA.
IPR013986. DExx_box_DNA_helicase_dom.
IPR014017. DNA_helicase_UvrD-like_C.
IPR000212. DNA_helicase_UvrD/REP.
IPR027417. P-loop_NTPase.
IPR014016. UvrD-like_ATP-bd.
[Graphical view]
PANTHERiPTHR11070. PTHR11070. 1 hit.
PfamiPF00580. UvrD-helicase. 1 hit.
PF13361. UvrD_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01073. pcrA. 1 hit.
PROSITEiPS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
PS51217. UVRD_HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25745 / 183-1wImported.

Entry informationi

Entry nameiQ03EG2_PEDPA
AccessioniPrimary (citable) accession number: Q03EG2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: April 1, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.