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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:PEPE_1846
OrganismiPediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)
Taxonomic identifieri278197 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaePediococcus
Proteomesi
  • UP000000773 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000214411 – 119Ribonuclease P protein componentAdd BLAST119

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi278197.PEPE_1846.

Structurei

3D structure databases

ProteinModelPortaliQ03D57.
SMRiQ03D57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105M7T. Bacteria.
COG0594. LUCA.
HOGENOMiHOG000266301.
KOiK03536.
OMAiFEACIRR.
OrthoDBiPOG091H01XK.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P. 1 hit.
InterProiView protein in InterPro
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
PANTHERiPTHR33992. PTHR33992. 1 hit.
PfamiView protein in Pfam
PF00825. Ribonuclease_P. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003629. Ribonuclease_P. 1 hit.
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q03D57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKSYRIKKE LEFQKVFETR NSFANKKFVV YVMDKPEQPH FRVGISVGKK
60 70 80 90 100
IGNAVMRNYT KRRIRQSILE FKPLLRQDVD FLVIARPQAS GLPMNEVKQQ
110
LEHVFKLAGL FASKQSEEE
Length:119
Mass (Da):14,016
Last modified:November 14, 2006 - v1
Checksum:iEB003401B239DC5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000422 Genomic DNA. Translation: ABJ68865.1.
RefSeqiWP_002833858.1. NC_008525.1.

Genome annotation databases

EnsemblBacteriaiABJ68865; ABJ68865; PEPE_1846.
GeneIDi33062907.
KEGGippe:PEPE_1846.

Similar proteinsi

Entry informationi

Entry nameiRNPA_PEDPA
AccessioniPrimary (citable) accession number: Q03D57
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: September 27, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families