Q03BB6 (GALT_LACC3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Galactose-1-phosphate uridylyltransferase
Short name=Gal-1-P uridylyltransferase
EC=2.7.7.12

Alternative name(s):
UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	LSEI_0666

Organism

Lactobacillus casei (strain ATCC 334) [Complete proteome] [HAMAP]

Taxonomic identifier

321967 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	486 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 486	486	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_1000025023

Sequences

	Sequence		Length	Mass (Da)
	Q03BB6 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 76CF53BFA3E9F5A9	FASTA	486	54,304
	10 20 30 40 50 60 MTAISNHIDT IIKLNPDYTQ MDAVYLTNKL LNLIGDAALE LPGDTDPLTN LDLMVKAAQD 70 80 90 100 110 120 NGKIPDSQAA RQILEAQLMD FATPTPSRIN QLFWDKYQAG PRVATDWFFA LSRANNYIQT 130 140 150 160 170 180 RAIAKNVVFP AKTEYGDLEI TINLSKPEKD PKDIAAAAHA TQSGYPACAL CLQTEGYAGR 190 200 210 220 230 240 TDFAARTNHR VIRFLLGGKT WGFQYSPYAY FNEHAIFLDA IHEPMVIDQS TFSNLLNIVT 250 260 270 280 290 300 MFPTYFVGSN ADLPIVGGSM LAHEHYQGGR HTFPMAKAPI ETQVEISGHP HVFAGIVKWP 310 320 330 340 350 360 MSVIRLVSAD SDELINAAEH VRQVWNQYTD ETVDVRAFVD GKPHHTVTPI ARRVGTEFQL 370 380 390 400 410 420 DLVLRDNQTS AQYPDGIFHP HQDVQHIKKE NIGLIEVMGR AILPARLKSE LAEVQKYLLG 430 440 450 460 470 480 EANTMKPMHQ AWADQLKAKY DWTPANAEIQ MQAAVGRVFA RVLEDAGVFK RDEVGQKAFA RFCRAL

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 334.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000423 Genomic DNA. Translation: ABJ69506.1.
RefSeq	YP_805948.1. NC_008526.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q03BB6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4419614.
GenomeReviews	Gene locus LSEI_0666 in contig CP000423_GR.
KEGG	lca:LSEI_0666.
PATRIC	22205020. VBILacCas62221_0670.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4468.
HOGENOM	HBG337915.
OMA	TWGFQYS.
ProtClustDB	PRK05270.
Enzyme and pathway databases
BioCyc	LCAS321967:LSEI_0666-MONOMER.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR023425. GalP_uridyl_Trfase_II_CS. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
KO	K00965.
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. GalT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_LACC3

Accession

Primary (citable) accession number: Q03BB6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 14, 2006
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program