Q03B21LUXS_LACP3S-ribosylhomocysteine lyase4.4.1.21AI-2 synthesis proteinAutoinducer-2 production protein LuxSluxSLSEI_0765Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 / NRRL B-441)Lactobacillus paracaseiBacteriaBacillotaBacilliLactobacillalesLactobacillaceaeLacticaseibacillusComparative genomics of the lactic acid bacteria.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteineFe cationBinds 1 Fe cation per subunit.Homodimer.Belongs to the LuxS family.Autoinducer synthesisIronLyaseMetal-bindingQuorum sensingReference proteomeFe cationFe cationFe cationMAKVESFTLDHTAVKAPYVRLITTEHGAKGDVISNYDLRLVQPNTAAIDTAGLHTIEHLLASLLRDRMDGVIDCSPFGCRTGFHLITWGEHSTTEVAKALKSSLEAIANDITWDDVPGVDIKSCGNYKDHSLFSAKEWAKLILSRGISNDPYTRQVV
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