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Protein

Protein RecA

Gene

recA

Organism
Lactobacillus casei (strain ATCC 334)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi66 – 738ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, DNA-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciLCAS321967:GH4S-922-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotationSAAS annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
Ordered Locus Names:LSEI_0923Imported
OrganismiLactobacillus casei (strain ATCC 334)Imported
Taxonomic identifieri321967 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000001651 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ03AQ0.
SMRiQ03AQ0. Positions 5-330.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini36 – 195160RECA_2InterPro annotationAdd
BLAST
Domaini200 – 27374RECA_3InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the RecA family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000264120.
KOiK03553.
OMAiTRKGAWY.

Family and domain databases

CDDicd00983. recA. 1 hit.
Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q03AQ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGDERQKAL DVALKKIEKN FGKGAIMRMG AKADTRVSVV SSGSLAVDDA
60 70 80 90 100
LGVGGFPRGR IVEIYGPESS GKTTVALHAV AEVQKQGGTA AYIDAENAMD
110 120 130 140 150
PKYATALGVN IDELLLSQPD TGEQGLEIAD ELVASGAIDI VVIDSVAALV
160 170 180 190 200
PRAEIEGDMG DAHVGLQARL MSQALRKLSG SINKTKTIAL FINQIREKVG
210 220 230 240 250
IIFGSPETTP GGRALKFYAT VRLEIRRSEQ IKTGADVVGN RTKIKVVKNK
260 270 280 290 300
VAPPFRTAIV DIMYGQGISQ TGELVDMAVE RDIVEKAGSW YAYQGERIGQ
310 320 330 340 350
GRENAKTYLD NHADLQQTIK QQVRVAYGMA SAPCPETASV SEDQPEIPQP

AEV
Length:353
Mass (Da):37,678
Last modified:November 14, 2006 - v1
Checksum:i51FF41E1D995DEE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000423 Genomic DNA. Translation: ABJ69722.1.
RefSeqiWP_011674321.1. NC_008526.1.
YP_806164.1. NC_008526.1.

Genome annotation databases

EnsemblBacteriaiABJ69722; ABJ69722; LSEI_0923.
GeneIDi4419320.
KEGGilca:LSEI_0923.
PATRICi22205541. VBILacCas62221_0893.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000423 Genomic DNA. Translation: ABJ69722.1.
RefSeqiWP_011674321.1. NC_008526.1.
YP_806164.1. NC_008526.1.

3D structure databases

ProteinModelPortaliQ03AQ0.
SMRiQ03AQ0. Positions 5-330.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ69722; ABJ69722; LSEI_0923.
GeneIDi4419320.
KEGGilca:LSEI_0923.
PATRICi22205541. VBILacCas62221_0893.

Phylogenomic databases

HOGENOMiHOG000264120.
KOiK03553.
OMAiTRKGAWY.

Enzyme and pathway databases

BioCyciLCAS321967:GH4S-922-MONOMER.

Family and domain databases

CDDicd00983. recA. 1 hit.
Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ03AQ0_LACC3
AccessioniPrimary (citable) accession number: Q03AQ0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: September 7, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.