Q03988 (Q03988_LYSSH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mosquitocidal toxin EMBL AAA22601.1

Gene names

Name:

mtx1 EMBL AAN04906.1

Organism

Lysinibacillus sphaericus (Bacillus sphaericus) EMBL AAA22601.1

Taxonomic identifier

1421 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Lysinibacillus

Protein attributes

Sequence length	870 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 2VSA PDB 2CB4 PDB 2VSE PDB 2CB6
Gene Ontology (GO)
None. [Check GOA]

Sequences

	Sequence		Length	Mass (Da)
	Q03988 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: E47FDDEAFD142E7E	FASTA	870	100,577
	10 20 30 40 50 60 MAIKKVLKII LAIIIIISCQ LPLNQKTVYA SPNSPKDNTW IQAASLTWLM DMSSLLYQLI 70 80 90 100 110 120 STRIPSFASP NGLHMREQTI DSNTGQIQID NEHRLLRWDR RPPNDIFLNG FIPRVTNQNL 130 140 150 160 170 180 SPVEDTHLLN YLRTNSPSIF VSTTRARYNN LGLEITPWTP HSANNNIIYR YEIFAPGGID 190 200 210 220 230 240 INASFSRNHN PFPNEDEITF PGGIRPEFIR STYEYHNGEI VRIWINPNFI NPSTLNDVSG 250 260 270 280 290 300 PSNISKVFWH ENHSEGNNMD SKGFILDLDY NQDFDMFAPN GEIPNNNLLN NNSLNVIQNS 310 320 330 340 350 360 EYQIKNKKDR NIVVTLDSDY GGSPVESYKN FGFENQKWNI KYDSKKNAYK IYNRETPTLL 370 380 390 400 410 420 LSWNSNSSNG EQVIRGYTES GSNNQYWTIE KNVNGFYKFR NLSDPSKILD LKDGNTLNKT 430 440 450 460 470 480 PLVVSSENSS SSQEWLIEKT NYQTVKDGTY QVSSKLNENK VIEQISTNKV HIFSNSDKEN 490 500 510 520 530 540 QVWNLIYNPI LKAYKIKSLK YPNYSLAWDS NNTRTIVAAT GDYNDQYWLI ERNEDNTYII 550 560 570 580 590 600 RNYENRKIVL DLSNGSTTDG NGLLGFEFHG GINQRWIIKP FSFNSIQDGI YQFMTVINQD 610 620 630 640 650 660 LIADLTTNNY TIATKTNNYS SNQKWTVTYN DKKRAYKIRN LQHAHLSLAW DSNHSDKIFG 670 680 690 700 710 720 ATGDYDDQYW IPILQTDGSF IFRNYKNPNK IFGTNGQPIN DIPLKAQDVT GQNNQKWYLR 730 740 750 760 770 780 HLNSSNNFTG YFNISSKKNF NKIITMNSNK TQAVIFDNIG INNQSWKLKY NDNKNAYQIH 790 800 810 820 830 840 ILDNFLYFQG GHNIVATMRN VTNDDLRSYW YVEYNFNKDG FIIRNAFDTS YVLDVFQGNF 850 860 870 ANNTPIITYQ NYLNDNQLWN FIPSLGVEPR

References

[1]	"Cloning, sequencing, and expression of a gene encoding a 100-kilodalton mosquitocidal toxin from Bacillus sphaericus SSII-1." Thanabalu T., Hindley J., Jackson-Yap J., Berry C. J. Bacteriol. 173:2776-2785(1991) [PubMed: 1840581] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SSII-1 EMBL AAA22601.1.
[2]	"Proteolytic processing of the mosquitocidal toxin from Bacillus sphaericus SSII-1." Thanabalu T., Hindley J., Berry C. J. Bacteriol. 174:5051-5056(1992) [PubMed: 1352768] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Structure of the mosquitocidal toxin from Bacillus sphaericus." Reinert D.J., Carpusca I., Aktories K., Schulz G.E. J. Mol. Biol. 357:1226-1236(2006) [PubMed: 16483607] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 30-308.
[4]	"Structure and mode of action of a mosquitocidal holotoxin." Treiber N., Reinert D.J., Carpusca I., Aktories K., Schulz G.E. J. Mol. Biol. 381:150-159(2008) [PubMed: 18586267] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 30-870.
[5]	"Toxicity of Bacillus sphaericus LP1-G against susceptible and resistant Culex quinquefasciatus and the cloning of the mosquitocidal toxin gene." Shi Y.X., Zheng D.S., Yuan Z.M. Curr. Microbiol. 47:226-230(2003) [PubMed: 14570274] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: LP1-G EMBL AAN04906.1.
[6]	"Cloning and expression in Escherichia coli of the mosquitocidal toxin gene from Bacillus sphaericus strain LP1-G." Shi R., Cai Q., Yan J., Yuan Z. Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: LP1-G EMBL AAN04906.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

M60446 Genomic DNA. Translation: AAA22601.1.
AF538928 Genomic DNA. Translation: AAN04906.1.

PIR

S27514. B44916.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2CB4	X-ray	2.50	A/B/C/D/E/F/G/H/I/J/K/L/M/N	30-308	[»]
2CB6	X-ray	3.00	A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P	30-308	[»]
2VSA	X-ray	2.89	A	30-870	[»]
2VSE	X-ray	2.50	A/B	30-870	[»]

ProteinModelPortal

Q03988.

SMR

Q03988. Positions 33-298.

ModBase

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Protein family/group databases

CAZy

CBM13. Carbohydrate-Binding Module Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR008903. HA-17_C_botulinum.
IPR008997. Ricin_B-rel_lectin.
IPR000772. Ricin_B_lectin.
[Graphical view]

Pfam

PF05588. Botulinum_HA-17. 1 hit.
PF00652. Ricin_B_lectin. 2 hits.
[Graphical view]

SMART

SM00458. RICIN. 4 hits.
[Graphical view]

SUPFAM

SSF50370. RicinB_like. 4 hits.

PROSITE

PS50231. RICIN_B_LECTIN. 4 hits.
[Graphical view]

ProtoNet

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Entry information

Entry name

Q03988_LYSSH

Accession

Primary (citable) accession number: Q03988

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	September 21, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)