Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q03964

- YD17A_YEAST

UniProt

Q03964 - YD17A_YEAST

Protein

Transposon Ty1-DR2 Gag polyprotein

Gene

TY1A-DR2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription By similarity.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei401 – 4022Cleavage; by Ty1 proteaseBy similarity

    GO - Molecular functioni

    1. RNA binding Source: SGD

    GO - Biological processi

    1. transposition, RNA-mediated Source: SGD

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transposon Ty1-DR2 Gag polyprotein
    Alternative name(s):
    Gag-p49
    Transposon Ty1 protein A
    Short name:
    TY1A
    Short name:
    TYA
    p58
    Cleaved into the following 2 chains:
    Capsid protein
    Short name:
    CA
    Alternative name(s):
    Gag-p45
    p54
    Gene namesi
    Name:TY1A-DR2
    Ordered Locus Names:YDR170W-A
    ORF Names:YD9395.02
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome IV

    Organism-specific databases

    CYGDiYDR170w-a.
    SGDiS000007227. YDR170W-A.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. retrotransposon nucleocapsid Source: SGD

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 440440Transposon Ty1-DR2 Gag polyproteinPRO_0000279040Add
    BLAST
    Chaini1 – 401401Capsid proteinBy similarityPRO_0000279041Add
    BLAST
    Peptidei402 – 44039Gag-p4By similarityPRO_0000279042Add
    BLAST

    Proteomic databases

    MaxQBiQ03964.

    Expressioni

    Gene expression databases

    GenevestigatoriQ03964.

    Interactioni

    Subunit structurei

    Homotrimer.By similarity

    Protein-protein interaction databases

    BioGridi32223. 10 interactions.
    DIPiDIP-8799N.
    IntActiQ03964. 2 interactions.
    MINTiMINT-680391.
    STRINGi4932.YDR170W-A.

    Structurei

    3D structure databases

    ProteinModelPortaliQ03964.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni299 – 401103RNA-bindingBy similarityAdd
    BLAST

    Domaini

    The C-terminal RNA-binding region of CA is sufficient for all its nucleocapsid-like chaperone activities.By similarity

    Phylogenomic databases

    GeneTreeiENSGT00710000106943.
    HOGENOMiHOG000000740.
    OrthoDBiEOG7XPZG1.

    Family and domain databases

    InterProiIPR015820. Retrotransposon_Ty1A_N.
    [Graphical view]
    PfamiPF01021. TYA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q03964-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESQQLSQHS PISHGSACAS VTSKEVQTTQ DPLDISASKT EECEKVFTQA    50
    NSQQPTTPPS AAVPENHHHA SPQAAQVPLP QNGPYPQQRM MTPQQANISG 100
    WPVYGHPSLM PYPPYQMSPM YAPPGAQSQF TQYPQYVGTH LNTPSPESGN 150
    SFPDSSSAKS NMTSTNQHVR PPPILTSPND FLNWVKIYIK FLQNSNLGDI 200
    IPTATRKAVR QMTDDELTFL CHTFQLFALS QFLPTWVKDI LSVDYTDIMK 250
    ILSKSINKMQ SDTQEVNDIT TLANLHYNGS TPADAFEAEV TNILDRLKNN 300
    GIPINNKVAC QFIMRGLSGE YKFLRYARHR YIHMTVADLF SDIHSMYEEQ 350
    QESKRNKSTY RRSPSDEKKD SRTYTNTTKP KSITRNSQKP NNSQSRTARA 400
    HNVSTSNNFP GPDNDLIRGS TTEPIQLKNK HDLHLRPGTY 440
    Length:440
    Mass (Da):49,445
    Last modified:November 1, 1996 - v1
    Checksum:i5E10CEE8878CD80E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z46727 Genomic DNA. Translation: CAA86697.1.
    BK006938 Genomic DNA. Translation: DAA12012.1.
    PIRiS49765.
    RefSeqiNP_010455.1. NM_001184320.1.

    Genome annotation databases

    EnsemblFungiiYDR170W-A; YDR170W-A; YDR170W-A.
    GeneIDi851750.
    KEGGisce:YDR170W-A.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z46727 Genomic DNA. Translation: CAA86697.1 .
    BK006938 Genomic DNA. Translation: DAA12012.1 .
    PIRi S49765.
    RefSeqi NP_010455.1. NM_001184320.1.

    3D structure databases

    ProteinModelPortali Q03964.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 32223. 10 interactions.
    DIPi DIP-8799N.
    IntActi Q03964. 2 interactions.
    MINTi MINT-680391.
    STRINGi 4932.YDR170W-A.

    Proteomic databases

    MaxQBi Q03964.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YDR170W-A ; YDR170W-A ; YDR170W-A .
    GeneIDi 851750.
    KEGGi sce:YDR170W-A.

    Organism-specific databases

    CYGDi YDR170w-a.
    SGDi S000007227. YDR170W-A.

    Phylogenomic databases

    GeneTreei ENSGT00710000106943.
    HOGENOMi HOG000000740.
    OrthoDBi EOG7XPZG1.

    Miscellaneous databases

    NextBioi 969504.

    Gene expression databases

    Genevestigatori Q03964.

    Family and domain databases

    InterProi IPR015820. Retrotransposon_Ty1A_N.
    [Graphical view ]
    Pfami PF01021. TYA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
      Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
      , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
      Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.

    Entry informationi

    Entry nameiYD17A_YEAST
    AccessioniPrimary (citable) accession number: Q03964
    Secondary accession number(s): D6VSF2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 6, 2007
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Retrotransposons are mobile genetic entities that are able to replicate via an RNA intermediate and a reverse transcription step. In contrast to retroviruses, retrotransposons are non-infectious, lack an envelope and remain intracellular. Ty1 retrotransposons belong to the copia elements (pseudoviridae).

    Keywords - Technical termi

    Complete proteome, Reference proteome, Transposable element

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome IV
      Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

    External Data

    Dasty 3