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Protein
Submitted name:

tRNA and rRNA cytosine-C5-methylase

Gene

LSEI_1624

Organism
Lactobacillus paracasei (strain ATCC 334 / BCRC 17002 / CIP 107868 / KCTC 3260 / NRRL B-441)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei284S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei312S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei331S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei384NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
tRNA and rRNA cytosine-C5-methylaseImported
Gene namesi
Ordered Locus Names:LSEI_1624Imported
OrganismiLactobacillus paracasei (strain ATCC 334 / BCRC 17002 / CIP 107868 / KCTC 3260 / NRRL B-441)Imported
Taxonomic identifieri321967 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000001651 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ038H4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini169 – 445SAM_MT_RSMB_NOPInterPro annotationAdd BLAST277

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR031341. Methyltr_RsmF_N.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF17125. Methyltr_RsmF_N. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q038H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPNNPRLLA VETLSRVTGQ GGYSNLTLDH VINSHKLTPR DAGLLTNIVY
60 70 80 90 100
GVIQRQLTLD FYLAPFIKGR KLDNWIRCLL DTAVYQLQYL DKVPARAVFF
110 120 130 140 150
DSTEIAKKLG HQGIAKFVTG VLRNAQRTGF PDPAAIADPV KRLSIESSTP
160 170 180 190 200
VWLVEKLTAQ LGEPKTRAIL NVINVPAHAS LRVNTTKITP AALLASLKPE
210 220 230 240 250
FPDLKESPLT PIGLIAPSGH LAGTSAFVKG EYTMQDESSM LVAPSLDIQP
260 270 280 290 300
GDVVLDACAA PGGKTTHIAQ YLDPKQGGQV TALDLHANKV RLINKNAKRL
310 320 330 340 350
GLTDRIHAQV LDARKVATTF PANSFDKILV DAPCSGLGLI RRKPEIKYTK
360 370 380 390 400
TPEDPAHLQQ IQLAILNSVA PTLKIGGRLT YSTCTMVKEE NQDVVAQFLA
410 420 430 440
AHPEFEQVSV PTLKPLHKAH NAPALQLFPD DYDTDGFFIA SLIRRK
Length:446
Mass (Da):48,664
Last modified:November 14, 2006 - v1
Checksum:iECBFE04CDB0E452E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000423 Genomic DNA. Translation: ABJ70398.1.
RefSeqiWP_011674551.1. NC_008526.1.
YP_806840.1. NC_008526.1.

Genome annotation databases

EnsemblBacteriaiABJ70398; ABJ70398; LSEI_1624.
GeneIDi4419024.
KEGGilca:LSEI_1624.
PATRICifig|321967.11.peg.1605.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ038H4_LACP3
AccessioniPrimary (citable) accession number: Q038H4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: June 7, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported