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Protein

V-type ATPase assembly factor PKR1

Gene

PKR1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V0.1 Publication

Miscellaneous

Present with 5750 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • vacuolar proton-transporting V-type ATPase complex assembly Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-32816-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
V-type ATPase assembly factor PKR1
Gene namesi
Name:PKR1
Ordered Locus Names:YMR123W
ORF Names:YM8564.05
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR123W.
SGDiS000004730. PKR1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 20CytoplasmicSequence analysisAdd BLAST20
Transmembranei21 – 41HelicalSequence analysisAdd BLAST21
Topological domaini42 – 46LumenalSequence analysis5
Transmembranei47 – 67HelicalSequence analysisAdd BLAST21
Topological domaini68 – 122CytoplasmicSequence analysisAdd BLAST55

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002032971 – 122V-type ATPase assembly factor PKR1Add BLAST122

Proteomic databases

PRIDEiQ03880.
TopDownProteomicsiQ03880.

Interactioni

Protein-protein interaction databases

BioGridi35300. 451 interactors.
DIPiDIP-4436N.
IntActiQ03880. 5 interactors.
MINTiMINT-545112.
STRINGi4932.YMR123W.

Structurei

3D structure databases

ProteinModelPortaliQ03880.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PKR1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000248859.
InParanoidiQ03880.
OMAiWEKVSEN.
OrthoDBiEOG092C5N5Y.

Family and domain databases

InterProiView protein in InterPro
IPR013945. Pkr1.
PANTHERiPTHR28251. PTHR28251. 1 hit.
PfamiView protein in Pfam
PF08636. Pkr1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q03880-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANFFVRLWE SVFEPGTSPQ LIIATHVSFV ALLLTLIWLI YATNGNIHFY
60 70 80 90 100
ALFCISLLLW ITVIWFINEL SHVKLKDNDE LDKDANKKDD SAIKEDSEDK
110 120
QESGKSTSTA RRTQAQSRSR KA
Length:122
Mass (Da):13,962
Last modified:November 1, 1997 - v1
Checksum:i5CAA6929D55F2C40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49273 Genomic DNA. Translation: CAA89272.1.
AY558408 Genomic DNA. Translation: AAS56734.1.
BK006946 Genomic DNA. Translation: DAA10020.1.
PIRiS54492.
RefSeqiNP_013842.1. NM_001182624.1.

Genome annotation databases

EnsemblFungiiYMR123W; YMR123W; YMR123W.
GeneIDi855153.
KEGGisce:YMR123W.

Similar proteinsi

Entry informationi

Entry nameiPKR1_YEAST
AccessioniPrimary (citable) accession number: Q03880
Secondary accession number(s): D6VZU6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 22, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names