Q03829 (YM39_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized mitochondrial carrier YMR166C

Gene names

Ordered Locus Names:	YMR166C
ORF Names:	YM8520.15C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	368 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion inner membrane; Multi-pass membrane protein Potential.
Miscellaneous	Present with 2060 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification] Contains 3 Solcar repeats.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Domain	Repeat Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from sequence model PubMed 12192589. Source: SGD mitochondrial inner membrane Inferred from sequence or structural similarity PubMed 10930523. Source: SGD
Molecular_function	transporter activity Inferred from sequence or structural similarity PubMed 10930523. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 368	368	Uncharacterized mitochondrial carrier YMR166C		PRO_0000090699
Regions
	Transmembrane	56 – 77	22	Helical; Name=1; Potential
	Transmembrane	115 – 135	21	Helical; Name=2; Potential
	Transmembrane	149 – 165	17	Helical; Name=3; Potential
	Transmembrane	219 – 239	21	Helical; Name=4; Potential
	Transmembrane	260 – 280	21	Helical; Name=5; Potential
	Transmembrane	332 – 353	22	Helical; Name=6; Potential
	Repeat	51 – 138	88	Solcar 1
	Repeat	146 – 240	95	Solcar 2
	Repeat	254 – 360	107	Solcar 3

Sequences

	Sequence		Length	Mass (Da)
	Q03829 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: B583100018DF045D	FASTA	368	40,992
	10 20 30 40 50 60 MNSWNLSSSI PIIHTPHDHP PTSEGTPDQP NNNRKDDKLH KKRGDSDEDL SPIWHCVVSG 70 80 90 100 110 120 GIGGKIGDSA MHSLDTVKTR QQGAPNVKKY RNMISAYRTI WLEEGVRRGL YGGYMAAMLG 130 140 150 160 170 180 SFPSAAIFFG TYEYTKRTMI EDWQINDTIT HLSAGFLGDF ISSFVYVPSE VLKTRLQLQG 190 200 210 220 230 240 RFNNPFFQSG YNYSNLRNAI KTVIKEEGFR SLFFGYKATL ARDLPFSALQ FAFYEKFRQL 250 260 270 280 290 300 AFKIEQKDGR DGELSIPNEI LTGACAGGLA GIITTPMDVV KTRVQTQQPP SQSNKSYSVT 310 320 330 340 350 360 HPHVTNGRPA ALSNSISLSL RTVYQSEGVL GFFSGVGPRF VWTSVQSSIM LLLYQMTLRG LSNAFPTD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. , Skelton J., Walsh S.V., Whitehead S., Barrell B.G. Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z49705 Genomic DNA. Translation: CAA89802.1. AY558121 Genomic DNA. Translation: AAS56447.1. BK006946 Genomic DNA. Translation: DAA10062.1.
PIR	S54524.
RefSeq	NP_013889.1. NM_001182670.1.
3D structure databases
ProteinModelPortal	Q03829.
SMR	Q03829. Positions 58-367.
ModBase	Search...
Protein-protein interaction databases
STRING	4932.YMR166C.
Proteomic databases
PaxDb	Q03829.
PeptideAtlas	Q03829.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YMR166C; YMR166C; YMR166C.
GeneID	855202.
KEGG	sce:YMR166C.
Organism-specific databases
CYGD	YMR166c.
SGD	S000004776. YMR166C.
Phylogenomic databases
eggNOG	NOG247316.
GeneTree	ENSGT00640000092016.
HOGENOM	HOG000180802.
OMA	LQGRYNN.
OrthoDB	EOG4G1QRF.
Gene expression databases
Genevestigator	Q03829.
GermOnline	YMR166C. Saccharomyces cerevisiae.
Family and domain databases
Gene3D	1.50.40.10. 1 hit.
InterPro	IPR002067. Mit_carrier. IPR018108. Mitochondrial_sb/sol_carrier. IPR023395. Mt_carrier_dom. [Graphical view]
Pfam	PF00153. Mito_carr. 3 hits. [Graphical view]
PRINTS	PR00926. MITOCARRIER.
SUPFAM	SSF103506. Mitoch_carrier. 1 hit.
PROSITE	PS50920. SOLCAR. 3 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	978690.

Entry information

Entry name

YM39_YEAST

Accession

Primary (citable) accession number: Q03829
Secondary accession number(s): D6VZY8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 97 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program