Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q03824 (INP2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Inheritance of peroxisomes protein 2
Gene names
Name:INP2
Ordered Locus Names:YMR163C
ORF Names:YM8520.12C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length705 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for peroxisome inheritance. Acts as the peroxisome-specific receptor for the myosin V motor MYO2. Ref.5

Subunit structure

Interacts with MYO2. Ref.5

Subcellular location

Peroxisome membrane; Single-pass membrane protein Ref.3 Ref.5.

Miscellaneous

Present with 736 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the INP2 family.

Ontologies

Binary interactions

With

Entry

#Exp.

IntAct

Notes

MYO2P195243EBI-27354,EBI-11659
PEX19Q074183EBI-27354,EBI-292

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 705705Inheritance of peroxisomes protein 2
PRO_0000203314

Regions

Transmembrane215 – 23117Helical; Potential

Amino acid modifications

Glycosylation2751N-linked (GlcNAc...) Potential
Glycosylation3431N-linked (GlcNAc...) Potential
Glycosylation3441N-linked (GlcNAc...) Potential
Glycosylation3791N-linked (GlcNAc...) Potential
Glycosylation5171N-linked (GlcNAc...) Potential
Glycosylation5691N-linked (GlcNAc...) Potential
Glycosylation5741N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q03824 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: E4F2A4D205A98F66

FASTA70581,467
        10         20         30         40         50         60 
MTTNSRPSAL QAPGLQIFSM LKSSEEDGFM SSSLTLDSDN IIGVTENNRQ EFYSTWRKPS 

        70         80         90        100        110        120 
LLSSRSVLHE YSPTIVGSND CTFSPITVGK TTKFFNWDDI ISRIFMQQPF GVTHQFFEEF 

       130        140        150        160        170        180 
RYSIITSHFL NDMNHYRLSL HLDQSIMNFH KSSTLLKNVP PKSVPFMATK YGKLAVAEDK 

       190        200        210        220        230        240 
KLYFRQNFNY LSMIITSYRV LTQLKKYCRK KNSPGLKRVV ILILVAVYLS IQQEYFRRHL 

       250        260        270        280        290        300 
ICYKTLLKVR KVLESLQQVD VMIHKYHLRF KEIKNHSFIS RVSLISIADE HSSVIKELLV 

       310        320        330        340        350        360 
FSSDALFYKL KSIIPDIVIF SDTSELSKYC ELYGIDVPNL YYNNTTTVKD LDGKLYRLKL 

       370        380        390        400        410        420 
LKKFMLCCLL SLDMTGNENL SNVNMRNALN KIFPDYMARV QLKKKYNPIG TFQNIVSLLR 

       430        440        450        460        470        480 
GLHSLLSTVL VSLNDHKQIL YAFPEETSTN TGCERANVCS FSKNDKLFQA LNYLKMIENN 

       490        500        510        520        530        540 
LLAIDIRNGI TENDRNIIED KLEELITFWK TSKICGNISR IQKVSPTNTI NHGFHLDILK 

       550        560        570        580        590        600 
GRKSPRSSSV QGLSLERKVD FIDVAESVND SFENDTELEE YEDYDCQEEC SAGSRQNHRV 

       610        620        630        640        650        660 
DFIGKDSCRK PDFKQLSDNE LRRKLDERIL KLAQENREGR ERLRTAKSFE LLRKAQASMS 

       670        680        690        700 
VKFGFQKPLR DDAFLESRPL SKCKVSSEET IPFLYELKGL LGNDS 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII."
Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. expand/collapse author list , Skelton J., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae."
Fagarasanu A., Fagarasanu M., Eitzen G.A., Aitchison J.D., Rachubinski R.A.
Dev. Cell 10:587-600(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH MYO2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49705 Genomic DNA. Translation: CAA89799.1.
BK006946 Genomic DNA. Translation: DAA10059.1.
PIRS54521.
RefSeqNP_013886.1. NM_001182667.1.

3D structure databases

ProteinModelPortalQ03824.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35340. 13 interactions.
DIPDIP-1673N.
IntActQ03824. 5 interactions.
MINTMINT-385667.
STRING4932.YMR163C.

Proteomic databases

PaxDbQ03824.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYMR163C; YMR163C; YMR163C.
GeneID855198.
KEGGsce:YMR163C.

Organism-specific databases

CYGDYMR163c.
SGDS000004773. INP2.

Phylogenomic databases

eggNOGNOG40466.
OMAITHIASM.
OrthoDBEOG7FJHBG.

Enzyme and pathway databases

BioCycYEAST:G3O-32853-MONOMER.

Gene expression databases

GenevestigatorQ03824.

Family and domain databases

InterProIPR026235. INP2.
IPR026859. Myosin-bd.
[Graphical view]
PfamPF12632. Vezatin. 1 hit.
[Graphical view]
PRINTSPR02104. INPROXISOME2.
ProtoNetSearch...

Other

NextBio978679.

Entry information

Entry nameINP2_YEAST
AccessionPrimary (citable) accession number: Q03824
Secondary accession number(s): D6VZY5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 11, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families