Q03799 (RT08_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
37S ribosomal protein S8, mitochondrial

Gene names

Name:	MRPS8
Ordered Locus Names:	YMR158W
ORF Names:	YM8520.07

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	155 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the mitochondrial small ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S). Ref.4
Subcellular location	Mitochondrion Ref.5.
Sequence similarities	Belongs to the ribosomal protein S8P family.

Ontologies

Keywords
Cellular component	Mitochondrion
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mitochondrial translation Inferred by curator Ref.4. Source: SGD
Cellular_component	mitochondrial small ribosomal subunit Inferred from physical interaction Ref.4. Source: SGD
Molecular_function	structural constituent of ribosome Inferred from physical interaction Ref.4. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 155	155	37S ribosomal protein S8, mitochondrial		PRO_0000126599

Sequences

	Sequence		Length	Mass (Da)
	Q03799 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 2C1C7F021627567A	FASTA	155	17,471
	10 20 30 40 50 60 MSLVKLANTC AHLQNCSKVR VALTSIPYTK LQLQFAYNLY QQGFLSSLQK GSTMGPDKDF 70 80 90 100 110 120 VEVTPDNIST RRLWVGLKYR DNKPVLSSCK LISKPNSRIH LPMEDMKKLC SGVTIRNIKP 130 140 150 LQPGELILVR AHNNIMDINE AISKKLDGEV LCRVK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. , Skelton J., Walsh S.V., Whitehead S., Barrell B.G. Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components." Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K. Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, MASS SPECTROMETRY.
[5]	"The proteome of Saccharomyces cerevisiae mitochondria." Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C. Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY. Strain: ATCC 76625 / YPH499.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z49705 Genomic DNA. Translation: CAA89794.1. AY558414 Genomic DNA. Translation: AAS56740.1. BK006946 Genomic DNA. Translation: DAA10053.1.
PIR	S54516.
RefSeq	NP_013879.1. NM_001182661.1.
3D structure databases
ProteinModelPortal	Q03799.
SMR	Q03799. Positions 4-154.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-6673N.
IntAct	Q03799. 6 interactions.
MINT	MINT-671659.
STRING	4932.YMR158W.
Proteomic databases
PaxDb	Q03799.
PeptideAtlas	Q03799.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YMR158W; YMR158W; YMR158W.
GeneID	855190.
KEGG	sce:YMR158W.
Organism-specific databases
CYGD	YMR158w.
SGD	S000004767. MRPS8.
Phylogenomic databases
eggNOG	COG0096.
HOGENOM	HOG000204096.
OMA	CAHLQNC.
OrthoDB	EOG48SM3Q.
Gene expression databases
Genevestigator	Q03799.
GermOnline	YMR158W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR000630. Ribosomal_S8. [Graphical view]
PANTHER	PTHR11758. PTHR11758. 1 hit.
Pfam	PF00410. Ribosomal_S8. 1 hit. [Graphical view]
SUPFAM	SSF56047. Ribosomal_S8. 1 hit.
PROSITE	PS00053. RIBOSOMAL_S8. False negative. [Graphical view]
ProtoNet	Search...
Other
NextBio	978659.

Entry information

Entry name

RT08_YEAST

Accession

Primary (citable) accession number: Q03799
Secondary accession number(s): D6VZX9

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 93 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program