Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Trafficking protein particle complex subunit 23

Gene

TRS23

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation.3 Publications

Miscellaneous

Present with 3130 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • autophagy Source: UniProtKB-KW
  • chromosome organization Source: SGD
  • ER to Golgi vesicle-mediated transport Source: SGD
  • regulation of molecular function Source: GOC

Keywordsi

Biological processAutophagy, ER-Golgi transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29819-MONOMER.
ReactomeiR-SCE-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Trafficking protein particle complex subunit 23
Short name:
TRAPP subunit 23
Alternative name(s):
Transport protein particle 23 kDa subunit
Gene namesi
Name:TRS23
Ordered Locus Names:YDR246W
ORF Names:YD8419.13
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR246W.
SGDiS000002654. TRS23.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002115711 – 219Trafficking protein particle complex subunit 23Add BLAST219

Proteomic databases

MaxQBiQ03784.
PRIDEiQ03784.

Interactioni

Subunit structurei

Part of the multisubunit TRAPP (transport protein particle) I complex composed of BET3, BET5, TRS20, TRS23, TRS31 and TRS33. Part of the multisubunit TRAPP (transport protein particle) II complex composed of BET3, BET5, TRS20, TRS23, TRS31, TRS33, TRS65, TRS85, TRS120 and TRS130. Part of the multisubunit TRAPP (transport protein particle) III complex composed of BET3, BET5, TRS20, TRS23, TRS31, TRS33 and TRS85.5 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
BET3P3614911EBI-19474,EBI-3567

Protein-protein interaction databases

BioGridi32297. 501 interactors.
DIPiDIP-5813N.
IntActiQ03784. 5 interactors.
MINTiMINT-640620.
STRINGi4932.YDR246W.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3CUEX-ray3.70A/G/M/S1-219[»]
ProteinModelPortaliQ03784.
SMRiQ03784.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ03784.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00510000047061.
HOGENOMiHOG000165619.
InParanoidiQ03784.
KOiK20303.
OMAiNEYLILA.
OrthoDBiEOG092C5E92.

Family and domain databases

InterProiView protein in InterPro
IPR011012. Longin-like_dom_sf.
IPR007233. TRAPPC.
PANTHERiPTHR23249. PTHR23249. 1 hit.
PfamiView protein in Pfam
PF04099. Sybindin. 3 hits.
SMARTiView protein in SMART
SM01399. Sybindin. 1 hit.
SUPFAMiSSF64356. SSF64356. 2 hits.

Sequencei

Sequence statusi: Complete.

Q03784-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIETILVIN KSGGLIYQRN FTNDEQKLNS NEYLILASTL HGVFAIASQL
60 70 80 90 100
TPKALQLTQQ TNIENTIPYI PYVGMSSNRS DTRNGGGNNN KHTNNEKLGS
110 120 130 140 150
FKGDDFFKEP FTNWNKSGLR QLCTDQFTMF IYQTLTGLKF VAISSSVMPQ
160 170 180 190 200
RQPTIATTDK PDRPKSTSNL AIQIADNFLR KVYCLYSDYV MKDPSYSMEM
210
PIRSNLFDEK VKKMVENLQ
Length:219
Mass (Da):24,863
Last modified:November 1, 1996 - v1
Checksum:i8B32B1D5FE3846ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49701 Genomic DNA. Translation: CAA89732.1.
BK006938 Genomic DNA. Translation: DAA12086.1.
PIRiS54542.
RefSeqiNP_010532.3. NM_001180554.3.

Genome annotation databases

EnsemblFungiiYDR246W; YDR246W; YDR246W.
GeneIDi851833.
KEGGisce:YDR246W.

Similar proteinsi

Entry informationi

Entry nameiTRS23_YEAST
AccessioniPrimary (citable) accession number: Q03784
Secondary accession number(s): D6VSM6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names