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Protein

Glycogen synthase

Gene

glgA

Organism
Lactobacillus casei (strain ATCC 334)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei16 – 161ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciLCAS321967:GH4S-2036-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:LSEI_2037
OrganismiLactobacillus casei (strain ATCC 334)
Taxonomic identifieri321967 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000001651: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 481481Glycogen synthasePRO_1000014367Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi321967.LSEI_2037.

Structurei

3D structure databases

ProteinModelPortaliQ036T0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q036T0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLKVLFTAAE SAPFYKTGGL GDVTYALPKA IKKQGVDIRV AIPFYEKKFP
60 70 80 90 100
AKYLPKVKDL THFTLEMDGR PVYVGLKTIK LGDVTYYLID NRQYFDRDGL
110 120 130 140 150
YGYWDDGGRF GYFQMAVIEM LQVIEWIPDV IHANDWHTAF IPVLLKEKYG
160 170 180 190 200
WIKPYQQIKT QLTIHNLQFQ GWFPPSTLAT VFGIGREGFN DDGFGQDGSI
210 220 230 240 250
NWLKGGINYA DLVSTVSPSY AKEIQTPAFG EHLDGTLRKQ SGKLVGILNG
260 270 280 290 300
IDSEVYNPAT DQNLAYNYDA KNLAGKAKDK KALQDEMHLP KRTDPLFAMV
310 320 330 340 350
SRLTRQKGAD LLVDALENFL VQNNVQVVVL GTGDQDLEED LSSLQDRFPG
360 370 380 390 400
QLAVRIDFDE GLAQRIYAGA DYFMMPSAFE PSGLAQMMAM RYGTLPIVHE
410 420 430 440 450
TGGLRDSVLA YNAETGAGDG FSFWDYNAGV LTNILRMAKS VYADQPKVYA
460 470 480
KLQQHAMVKD FDWHHSAAEY LKGYQRILGK A
Length:481
Mass (Da):53,996
Last modified:November 14, 2006 - v1
Checksum:i079C74DEC1C6D7CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000423 Genomic DNA. Translation: ABJ70792.1.
RefSeqiYP_807234.1. NC_008526.1.

Genome annotation databases

EnsemblBacteriaiABJ70792; ABJ70792; LSEI_2037.
GeneIDi4420584.
KEGGilca:LSEI_2037.
PATRICi22207793. VBILacCas62221_2001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000423 Genomic DNA. Translation: ABJ70792.1.
RefSeqiYP_807234.1. NC_008526.1.

3D structure databases

ProteinModelPortaliQ036T0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi321967.LSEI_2037.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ70792; ABJ70792; LSEI_2037.
GeneIDi4420584.
KEGGilca:LSEI_2037.
PATRICi22207793. VBILacCas62221_2001.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciLCAS321967:GH4S-2036-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 334.

Entry informationi

Entry nameiGLGA_LACC3
AccessioniPrimary (citable) accession number: Q036T0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: January 7, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.