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Protein

Putative nucleotide-sugar transporter YMD8

Gene

YMD8

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • nucleotide-sugar transmembrane transporter activity Source: SGD

GO - Biological processi

  • carbohydrate transport Source: UniProtKB-KW
  • nucleotide-sugar transport Source: SGD
  • nucleotide transmembrane transport Source: GOC
  • UDP-glucose transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-32637-MONOMER.

Protein family/group databases

TCDBi2.A.7.9.14. the drug/metabolite transporter (dmt) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative nucleotide-sugar transporter YMD8
Gene namesi
Name:YMD8
Ordered Locus Names:YML038C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YML038C.
SGDiS000004502. YMD8.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 33CytoplasmicSequence analysis
Transmembranei4 – 2421HelicalSequence analysisAdd
BLAST
Topological domaini25 – 328ExtracellularSequence analysis
Transmembranei33 – 5321HelicalSequence analysisAdd
BLAST
Topological domaini54 – 7623CytoplasmicSequence analysisAdd
BLAST
Transmembranei77 – 9721HelicalSequence analysisAdd
BLAST
Topological domaini98 – 10710ExtracellularSequence analysis
Transmembranei108 – 12821HelicalSequence analysisAdd
BLAST
Topological domaini129 – 1324CytoplasmicSequence analysis
Transmembranei133 – 15321HelicalSequence analysisAdd
BLAST
Topological domaini154 – 16613ExtracellularSequence analysisAdd
BLAST
Transmembranei167 – 18721HelicalSequence analysisAdd
BLAST
Topological domaini188 – 25467CytoplasmicSequence analysisAdd
BLAST
Transmembranei255 – 27521HelicalSequence analysisAdd
BLAST
Topological domaini276 – 30126ExtracellularSequence analysisAdd
BLAST
Transmembranei302 – 32221HelicalSequence analysisAdd
BLAST
Topological domaini323 – 3297CytoplasmicSequence analysis
Transmembranei330 – 35021HelicalSequence analysisAdd
BLAST
Topological domaini351 – 3555ExtracellularSequence analysis
Transmembranei356 – 37621HelicalSequence analysisAdd
BLAST
Topological domaini377 – 44266CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasmic vesicle, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 442442Putative nucleotide-sugar transporter YMD8PRO_0000213402Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi99 – 991N-linked (GlcNAc...)Sequence analysis
Modified residuei209 – 2091PhosphoserineCombined sources

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiQ03697.

PTM databases

iPTMnetiQ03697.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CREB3L1Q96BA83EBI-27776,EBI-6942903From a different organism.

Protein-protein interaction databases

BioGridi35132. 108 interactions.
DIPiDIP-1312N.
IntActiQ03697. 9 interactions.
MINTiMINT-388216.

Structurei

3D structure databases

ProteinModelPortaliQ03697.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00510000048078.
HOGENOMiHOG000111198.
InParanoidiQ03697.
KOiK15280.
OMAiIFYISPS.
OrthoDBiEOG7J44H6.

Family and domain databases

InterProiIPR004853. Sugar_P_trans_dom.
[Graphical view]
PfamiPF03151. TPT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q03697-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRTVFLAFV FGWYFCSIAL SIYNRWMFDP KDGLGIGYPV LVTTFHQATL
60 70 80 90 100
WLLSGIYIKL RHKPVKNVLR KNNGFNWSFF LKFLLPTAVA SAGDIGLSNV
110 120 130 140 150
SFQYVPLTIY TIIKSSSIAF VLLFGCIFKL EKFHWKLALS VIIMFVGVAL
160 170 180 190 200
MVFKPSDSTS TKNDQALVIF GSFLVLASSC LSGLRWVYTQ LMLRNNPIQT
210 220 230 240 250
NTAAAVEESD GALFTENEDN VDNEPVVNLA NNKMLENFGE SKPHPIHTIH
260 270 280 290 300
QLAPIMGITL LLTSLLVEKP FPGIFSSSIF RLDTSNGGVG TETTVLSIVR
310 320 330 340 350
GIVLLILPGF AVFLLTICEF SILEQTPVLT VSIVGIVKEL LTVIFGIIIL
360 370 380 390 400
SERLSGFYNW LGMLIIMADV CYYNYFRYKQ DLLQKYHSVS TQDNRNELKG
410 420 430 440
FQDFEQLGSK KIAPYSISVD LTNQEYELDM IAQNVSRSSQ QV
Length:442
Mass (Da):49,615
Last modified:November 1, 1997 - v1
Checksum:i37A03543D3AB695E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46659 Genomic DNA. Translation: CAA86617.1.
AY692787 Genomic DNA. Translation: AAT92806.1.
BK006946 Genomic DNA. Translation: DAA09861.1.
PIRiS49741.
RefSeqiNP_013674.1. NM_001182396.1.

Genome annotation databases

EnsemblFungiiYML038C; YML038C; YML038C.
GeneIDi854970.
KEGGisce:YML038C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46659 Genomic DNA. Translation: CAA86617.1.
AY692787 Genomic DNA. Translation: AAT92806.1.
BK006946 Genomic DNA. Translation: DAA09861.1.
PIRiS49741.
RefSeqiNP_013674.1. NM_001182396.1.

3D structure databases

ProteinModelPortaliQ03697.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35132. 108 interactions.
DIPiDIP-1312N.
IntActiQ03697. 9 interactions.
MINTiMINT-388216.

Protein family/group databases

TCDBi2.A.7.9.14. the drug/metabolite transporter (dmt) superfamily.

PTM databases

iPTMnetiQ03697.

Proteomic databases

MaxQBiQ03697.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYML038C; YML038C; YML038C.
GeneIDi854970.
KEGGisce:YML038C.

Organism-specific databases

EuPathDBiFungiDB:YML038C.
SGDiS000004502. YMD8.

Phylogenomic databases

GeneTreeiENSGT00510000048078.
HOGENOMiHOG000111198.
InParanoidiQ03697.
KOiK15280.
OMAiIFYISPS.
OrthoDBiEOG7J44H6.

Enzyme and pathway databases

BioCyciYEAST:G3O-32637-MONOMER.

Miscellaneous databases

PROiQ03697.

Family and domain databases

InterProiIPR004853. Sugar_P_trans_dom.
[Graphical view]
PfamiPF03151. TPT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  6. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-209, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYMD8_YEAST
AccessioniPrimary (citable) accession number: Q03697
Secondary accession number(s): D6VZD7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 8, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.