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Reviewed, UniProtKB/Swiss-Prot Q03697 (YMD8_YEAST)

Last modified November 24, 2009. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Uncharacterized transporter YML038C
Gene names
Ordered Locus Names: YML038C
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length442 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the TPT transporter family. SLC35C subfamily.

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Ontologies

Keywords
   Biological processSugar transport
Transport
   Cellular componentMembrane
   DomainTransmembrane
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processUDP-glucose transport

Inferred from mutant phenotype. Source: SGD

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 442442Uncharacterized transporter YML038C
PRO_0000213402

Regions

Topological domain1 – 33Cytoplasmic Potential
Transmembrane4 – 2421 Potential
Topological domain25 – 328Extracellular Potential
Transmembrane33 – 5321 Potential
Topological domain54 – 7623Cytoplasmic Potential
Transmembrane77 – 9721 Potential
Topological domain98 – 10710Extracellular Potential
Transmembrane108 – 12821 Potential
Topological domain129 – 1324Cytoplasmic Potential
Transmembrane133 – 15321 Potential
Topological domain154 – 16613Extracellular Potential
Transmembrane167 – 18721 Potential
Topological domain188 – 25467Cytoplasmic Potential
Transmembrane255 – 27521 Potential
Topological domain276 – 30126Extracellular Potential
Transmembrane302 – 32221 Potential
Topological domain323 – 3297Cytoplasmic Potential
Transmembrane330 – 35021 Potential
Topological domain351 – 3555Extracellular Potential
Transmembrane356 – 37621 Potential
Topological domain377 – 44266Cytoplasmic Potential

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Sequences

Sequence LengthMass (Da)Tools
Q03697-1 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 37A03543D3AB695E

FASTA44249,615
        10         20         30         40         50         60 
MNRTVFLAFV FGWYFCSIAL SIYNRWMFDP KDGLGIGYPV LVTTFHQATL WLLSGIYIKL 

        70         80         90        100        110        120 
RHKPVKNVLR KNNGFNWSFF LKFLLPTAVA SAGDIGLSNV SFQYVPLTIY TIIKSSSIAF 

       130        140        150        160        170        180 
VLLFGCIFKL EKFHWKLALS VIIMFVGVAL MVFKPSDSTS TKNDQALVIF GSFLVLASSC 

       190        200        210        220        230        240 
LSGLRWVYTQ LMLRNNPIQT NTAAAVEESD GALFTENEDN VDNEPVVNLA NNKMLENFGE 

       250        260        270        280        290        300 
SKPHPIHTIH QLAPIMGITL LLTSLLVEKP FPGIFSSSIF RLDTSNGGVG TETTVLSIVR 

       310        320        330        340        350        360 
GIVLLILPGF AVFLLTICEF SILEQTPVLT VSIVGIVKEL LTVIFGIIIL SERLSGFYNW 

       370        380        390        400        410        420 
LGMLIIMADV CYYNYFRYKQ DLLQKYHSVS TQDNRNELKG FQDFEQLGSK KIAPYSISVD 

       430        440 
LTNQEYELDM IAQNVSRSSQ QV

« Hide

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References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII."
Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. expand/collapse author list , Skelton J., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:90-93(1997) [PubMed: 9169872] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

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Cross-references

Sequence databases

Z46659 Genomic DNA. Translation: CAA86617.1.
AY692787 Genomic DNA. Translation: AAT92806.1.
PIRS49741.
RefSeqNP_013674.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

DIPDIP:1312N.
IntActQ03697. 13 interactions.
STRINGQ03697.

Genome annotation databases

EnsemblYML038C; YML038C; YML038C; Saccharomyces cerevisiae. [Genome view]
GeneID854970.
KEGGsce:YML038C.
NMPDRfig|4932.3.peg.4714.

Organism-specific databases

CYGDYML038c.
SGDS000004502. YMD8.

Phylogenomic databases

HOGENOMQ03697.
OMATELNICG
OrthoDBEOG9PP00F

Gene expression databases

ArrayExpressQ03697.
GenevestigatorQ03697.
GermOnlineYML038C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR004853. DUF250.
[Graphical view]
PfamPF03151. TPT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio978070.

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Entry information

Entry nameYMD8_YEAST
AccessionPrimary (citable) accession number: Q03697
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 24, 2009
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents