Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q03686

- BIP8_TOBAC

UniProt

Q03686 - BIP8_TOBAC

Protein

Luminal-binding protein 8

Gene

BIP8

Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Luminal-binding protein 8
    Short name:
    BiP 8
    Alternative name(s):
    78 kDa glucose-regulated protein homolog 8
    Short name:
    GRP-78-8
    Gene namesi
    Name:BIP8
    OrganismiNicotiana tabacum (Common tobacco)
    Taxonomic identifieri4097 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum lumen Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 293›293Luminal-binding protein 8PRO_0000078669Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi244 – 2441N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ03686.

    Structurei

    3D structure databases

    ProteinModelPortaliQ03686.
    SMRiQ03686. Positions 1-212.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi290 – 2934Prevents secretion from ERPROSITE-ProRule annotation

    Sequence similaritiesi

    Belongs to the heat shock protein 70 family.Curated

    Family and domain databases

    Gene3Di1.20.1270.10. 1 hit.
    2.60.34.10. 1 hit.
    InterProiIPR029048. HSP70_C.
    IPR029047. HSP70_peptide-bd.
    IPR013126. Hsp_70_fam.
    [Graphical view]
    PfamiPF00012. HSP70. 1 hit.
    [Graphical view]
    PRINTSiPR00301. HEATSHOCK70.
    SUPFAMiSSF100920. SSF100920. 1 hit.
    SSF100934. SSF100934. 1 hit.
    PROSITEiPS00014. ER_TARGET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q03686-1 [UniParc]FASTAAdd to Basket

    « Hide

    RIPKVQQLLK DYFDGKEPNK GVNPDEAVAY GAAVQGGILS GEGGDETKDI    50
    LLLDVAPLTL GIETVGGVMT KLIPRNTVIP SKKSQVFTTY QDQQTTVTIQ 100
    VFEGERSLTK DCRLLGKFDL TGIAPAPRGT PQIEVTFEVD ANGILNVKAE 150
    DKASGKSEKI TITNDKGRLS QEEIERMVKE AEEFAEEDKK VKERIDARNS 200
    LETYVYNMRN QINDKDKLAD KLESDEKEKI ETATKEALEW LDDNQSAEKE 250
    DYEEKLKEVE AVCNPIITAV YQKSGGAPGG ESGASEDDDH DEL 293
    Length:293
    Mass (Da):32,342
    Last modified:February 1, 1995 - v1
    Checksum:i44939595E45650E6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60062 mRNA. Translation: CAA42664.1.
    PIRiS21881.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60062 mRNA. Translation: CAA42664.1 .
    PIRi S21881.

    3D structure databases

    ProteinModelPortali Q03686.
    SMRi Q03686. Positions 1-212.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q03686.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.20.1270.10. 1 hit.
    2.60.34.10. 1 hit.
    InterProi IPR029048. HSP70_C.
    IPR029047. HSP70_peptide-bd.
    IPR013126. Hsp_70_fam.
    [Graphical view ]
    Pfami PF00012. HSP70. 1 hit.
    [Graphical view ]
    PRINTSi PR00301. HEATSHOCK70.
    SUPFAMi SSF100920. SSF100920. 1 hit.
    SSF100934. SSF100934. 1 hit.
    PROSITEi PS00014. ER_TARGET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The tobacco luminal binding protein is encoded by a multigene family."
      Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
      Plant Cell 3:1025-1035(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. Erratum
      Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
      Plant Cell 3:1251-1251(1991)

    Entry informationi

    Entry nameiBIP8_TOBAC
    AccessioniPrimary (citable) accession number: Q03686
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3