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Q03686 (BIP8_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Luminal-binding protein 8

Short name=BiP 8
Alternative name(s):
78 kDa glucose-regulated protein homolog 8
Short name=GRP-78-8
Gene names
Name:BIP8
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length293 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

Subcellular location

Endoplasmic reticulum lumen.

Sequence similarities

Belongs to the heat shock protein 70 family.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   LigandATP-binding
Nucleotide-binding
   PTMGlycoprotein
Gene Ontology (GO)
   Cellular_componentendoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 293›293Luminal-binding protein 8
PRO_0000078669

Regions

Motif290 – 2934Prevents secretion from ER Potential

Amino acid modifications

Glycosylation2441N-linked (GlcNAc...) Potential

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q03686 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 44939595E45650E6

FASTA29332,342
        10         20         30         40         50         60 
RIPKVQQLLK DYFDGKEPNK GVNPDEAVAY GAAVQGGILS GEGGDETKDI LLLDVAPLTL 

        70         80         90        100        110        120 
GIETVGGVMT KLIPRNTVIP SKKSQVFTTY QDQQTTVTIQ VFEGERSLTK DCRLLGKFDL 

       130        140        150        160        170        180 
TGIAPAPRGT PQIEVTFEVD ANGILNVKAE DKASGKSEKI TITNDKGRLS QEEIERMVKE 

       190        200        210        220        230        240 
AEEFAEEDKK VKERIDARNS LETYVYNMRN QINDKDKLAD KLESDEKEKI ETATKEALEW 

       250        260        270        280        290 
LDDNQSAEKE DYEEKLKEVE AVCNPIITAV YQKSGGAPGG ESGASEDDDH DEL 

« Hide

References

[1]"The tobacco luminal binding protein is encoded by a multigene family."
Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
Plant Cell 3:1025-1035(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]Erratum
Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
Plant Cell 3:1251-1251(1991)

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X60062 mRNA. Translation: CAA42664.1.
PIRS21881.

3D structure databases

ProteinModelPortalQ03686.
SMRQ03686. Positions 1-212.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ03686.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProIPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSPR00301. HEATSHOCK70.
SUPFAMSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBIP8_TOBAC
AccessionPrimary (citable) accession number: Q03686
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families