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Q03685 (BIP5_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Luminal-binding protein 5

Short name=BiP 5
Alternative name(s):
78 kDa glucose-regulated protein homolog 5
Short name=GRP-78-5
Gene names
Name:BIP5
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length668 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

Subcellular location

Endoplasmic reticulum lumen.

Sequence similarities

Belongs to the heat shock protein 70 family.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   DomainSignal
   LigandATP-binding
Nucleotide-binding
   PTMGlycoprotein
Gene Ontology (GO)
   Cellular_componentendoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 668644Luminal-binding protein 5
PRO_0000013595

Regions

Motif665 – 6684Prevents secretion from ER Potential

Amino acid modifications

Glycosylation6171N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q03685 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 7980231A991DC590

FASTA66873,744
        10         20         30         40         50         60 
MAGAWKRRAS LIVFAIVLFG SLFAFSIAKE EATKLGTVIG IDLGTTYSCV GVYKNGHVEI 

        70         80         90        100        110        120 
IANDQGNRIT PSWVAFTDGE RLIGEAAKNQ AAVNPERTIF DVKRLIGRKF DDKEVQRDKK 

       130        140        150        160        170        180 
LVPYEIVNKD GKPYIQVKIK DGETKVFSPE EISAMILTKM KETAEAYLGK KIKDAVVTVP 

       190        200        210        220        230        240 
AYFNDAQRQA TKDAGVIAGL NVARIINEPT AAAIAYGLDK KGGEKNILVF DLGGGTFDVS 

       250        260        270        280        290        300 
ILTIDNGVFE VLATNGDTHL GGEDFDQRIM EYFIKLIKKK HGKDISKDNR ALGKLRREAE 

       310        320        330        340        350        360 
RAKRALSSQH QVRVEIESLF DGVDFSEPLT RARFEELNND LFRKTMGPVK KAMEDAGLEK 

       370        380        390        400        410        420 
NQIDEIVLVG GSTRIPKVQQ LLKDYFDGKE PNKGVNPDEA VAYGAAVQGG ILSGEGGDET 

       430        440        450        460        470        480 
KDILLLDVAP LTLGIETVGG VMTKLIPRNT VIPTKKSQVF TTYQDQQTTV TISVFEGERS 

       490        500        510        520        530        540 
LTKDCRLLGK FDLTGIAPAP RGTPQIEVTF EVDANGILNV KAEDKASGKS EKITITNDKG 

       550        560        570        580        590        600 
RLSQEEIERM VKEAEEFAEE DKKVKERIDA RNSLETYVYN MRNQINDKDK LADKLESDEK 

       610        620        630        640        650        660 
EKIETATKEA LEWLDDNQSA EKEDYDEKLK EVEAVCNPII TAVYQRSGGA PGGASEESNE 


DDDSHDEL 

« Hide

References

[1]"The tobacco luminal binding protein is encoded by a multigene family."
Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
Plant Cell 3:1025-1035(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]Erratum
Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
Plant Cell 3:1251-1251(1991)

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X60058 mRNA. Translation: CAA42660.1.
PIRS21880.

3D structure databases

ProteinModelPortalQ03685.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ03685.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR018181. Heat_shock_70_CS.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSPR00301. HEATSHOCK70.
PROSITEPS00014. ER_TARGET. 1 hit.
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBIP5_TOBAC
AccessionPrimary (citable) accession number: Q03685
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 19, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families