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Q03684 (BIP4_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Luminal-binding protein 4

Short name=BiP 4
Alternative name(s):
78 kDa glucose-regulated protein homolog 4
Short name=GRP-78-4
Gene names
Name:BIP4
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length667 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

Subcellular location

Endoplasmic reticulum lumen.

Sequence similarities

Belongs to the heat shock protein 70 family.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   DomainSignal
   LigandATP-binding
Nucleotide-binding
   PTMGlycoprotein
Gene Ontology (GO)
   Cellular_componentendoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 667642Luminal-binding protein 4
PRO_0000013594

Regions

Motif664 – 6674Prevents secretion from ER Potential

Amino acid modifications

Glycosylation6181N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q03684 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: D99278756EF7B2CA

FASTA66773,522
        10         20         30         40         50         60 
MAGGAWNRRT SLIVFGIVLF GCLFAFSIAT EEATKLGTVI GIDLGTTYSC VGVYKNGHVE 

        70         80         90        100        110        120 
IIANDQGNRI TPSWVAFTDG ERLIGEAAKN LAAVNPERTV FDVKRLIGRK FDDKEVQRDM 

       130        140        150        160        170        180 
KLVPYKIVNK DGKPYIQVKI KDGETKIFSP EEISAMILTK MKETAEAYLG KKIKDAVVTV 

       190        200        210        220        230        240 
PAYFNDAQRQ ATKDAGVIAG LNVARIINEP TAAAIAYGLD KKGGEKNILV FDLGGGTFDV 

       250        260        270        280        290        300 
SILTIDNGVF EVLSTNGDTH LGGEDFDQRI MEYFIKLIKK KHGKDISKDN RALGKLRREA 

       310        320        330        340        350        360 
ERAKRALSSQ HQVRVEIESL FDGVDFSEPL TRARFEELNN DLFRKTMGPV KKAMDDAGLE 

       370        380        390        400        410        420 
KTQIDEIVLV GGSTRIPKVQ QLLKDYFDGK EPNKGVNPDE AVAYGAAVQG GILSGEGGDE 

       430        440        450        460        470        480 
TKDILLLDVA PLTLGIETVG GVMTKLIPRN TVIPTKKSQV FTTYQDQQTT VTIQVFEGER 

       490        500        510        520        530        540 
SLTKDCRLLG KFDLTGIAPA PRGTPQIEVT FEVDANGILN VKAEDKASGK SEKITITNDK 

       550        560        570        580        590        600 
GRLSQEEIER MVKEAEEFAE EDKKVKERID ARNSLETYVY NMRNQINDKD KLADKLESDE 

       610        620        630        640        650        660 
KEKIETATKE ALEWLDDNQS AEKEDYEEKL KEVEAVCNPI ITAVYQKSGG APGGESGASE 


DDDHDEL 

« Hide

References

[1]"The tobacco luminal binding protein is encoded by a multigene family."
Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
Plant Cell 3:1025-1035(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]Erratum
Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
Plant Cell 3:1251-1251(1991)

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X60057 mRNA. Translation: CAA42659.1.
PIRS21879. JQ1360.

3D structure databases

ProteinModelPortalQ03684.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ03684.
ProMEXQ03684.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSPR00301. HEATSHOCK70.
SUPFAMSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBIP4_TOBAC
AccessionPrimary (citable) accession number: Q03684
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families