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Q03684

- BIP4_TOBAC

UniProt

Q03684 - BIP4_TOBAC

Protein

Luminal-binding protein 4

Gene

BIP4

Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Luminal-binding protein 4
    Short name:
    BiP 4
    Alternative name(s):
    78 kDa glucose-regulated protein homolog 4
    Short name:
    GRP-78-4
    Gene namesi
    Name:BIP4
    OrganismiNicotiana tabacum (Common tobacco)
    Taxonomic identifieri4097 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum lumen Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2525Sequence AnalysisAdd
    BLAST
    Chaini26 – 667642Luminal-binding protein 4PRO_0000013594Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi618 – 6181N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ03684.
    ProMEXiQ03684.

    Structurei

    3D structure databases

    ProteinModelPortaliQ03684.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi664 – 6674Prevents secretion from ERPROSITE-ProRule annotation

    Sequence similaritiesi

    Belongs to the heat shock protein 70 family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di1.20.1270.10. 1 hit.
    2.60.34.10. 1 hit.
    InterProiIPR018181. Heat_shock_70_CS.
    IPR029048. HSP70_C.
    IPR029047. HSP70_peptide-bd.
    IPR013126. Hsp_70_fam.
    [Graphical view]
    PfamiPF00012. HSP70. 1 hit.
    [Graphical view]
    PRINTSiPR00301. HEATSHOCK70.
    SUPFAMiSSF100920. SSF100920. 1 hit.
    SSF100934. SSF100934. 1 hit.
    PROSITEiPS00014. ER_TARGET. 1 hit.
    PS00297. HSP70_1. 1 hit.
    PS00329. HSP70_2. 1 hit.
    PS01036. HSP70_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q03684-1 [UniParc]FASTAAdd to Basket

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    MAGGAWNRRT SLIVFGIVLF GCLFAFSIAT EEATKLGTVI GIDLGTTYSC    50
    VGVYKNGHVE IIANDQGNRI TPSWVAFTDG ERLIGEAAKN LAAVNPERTV 100
    FDVKRLIGRK FDDKEVQRDM KLVPYKIVNK DGKPYIQVKI KDGETKIFSP 150
    EEISAMILTK MKETAEAYLG KKIKDAVVTV PAYFNDAQRQ ATKDAGVIAG 200
    LNVARIINEP TAAAIAYGLD KKGGEKNILV FDLGGGTFDV SILTIDNGVF 250
    EVLSTNGDTH LGGEDFDQRI MEYFIKLIKK KHGKDISKDN RALGKLRREA 300
    ERAKRALSSQ HQVRVEIESL FDGVDFSEPL TRARFEELNN DLFRKTMGPV 350
    KKAMDDAGLE KTQIDEIVLV GGSTRIPKVQ QLLKDYFDGK EPNKGVNPDE 400
    AVAYGAAVQG GILSGEGGDE TKDILLLDVA PLTLGIETVG GVMTKLIPRN 450
    TVIPTKKSQV FTTYQDQQTT VTIQVFEGER SLTKDCRLLG KFDLTGIAPA 500
    PRGTPQIEVT FEVDANGILN VKAEDKASGK SEKITITNDK GRLSQEEIER 550
    MVKEAEEFAE EDKKVKERID ARNSLETYVY NMRNQINDKD KLADKLESDE 600
    KEKIETATKE ALEWLDDNQS AEKEDYEEKL KEVEAVCNPI ITAVYQKSGG 650
    APGGESGASE DDDHDEL 667
    Length:667
    Mass (Da):73,522
    Last modified:February 1, 1995 - v1
    Checksum:iD99278756EF7B2CA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60057 mRNA. Translation: CAA42659.1.
    PIRiJQ1360. S21879.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60057 mRNA. Translation: CAA42659.1 .
    PIRi JQ1360. S21879.

    3D structure databases

    ProteinModelPortali Q03684.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q03684.
    ProMEXi Q03684.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.20.1270.10. 1 hit.
    2.60.34.10. 1 hit.
    InterProi IPR018181. Heat_shock_70_CS.
    IPR029048. HSP70_C.
    IPR029047. HSP70_peptide-bd.
    IPR013126. Hsp_70_fam.
    [Graphical view ]
    Pfami PF00012. HSP70. 1 hit.
    [Graphical view ]
    PRINTSi PR00301. HEATSHOCK70.
    SUPFAMi SSF100920. SSF100920. 1 hit.
    SSF100934. SSF100934. 1 hit.
    PROSITEi PS00014. ER_TARGET. 1 hit.
    PS00297. HSP70_1. 1 hit.
    PS00329. HSP70_2. 1 hit.
    PS01036. HSP70_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The tobacco luminal binding protein is encoded by a multigene family."
      Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
      Plant Cell 3:1025-1035(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. Erratum
      Denecke J., Goldman M.H., Demolder J., Seurinck J., Botterman J.
      Plant Cell 3:1251-1251(1991)

    Entry informationi

    Entry nameiBIP4_TOBAC
    AccessioniPrimary (citable) accession number: Q03684
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3