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Protein

Luminal-binding protein 2

Gene

BIP2

Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Luminal-binding protein 2
Short name:
BiP 2
Alternative name(s):
78 kDa glucose-regulated protein homolog 2
Short name:
GRP-78-2
Gene namesi
Name:BIP2
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000078667‹1 – 292Luminal-binding protein 2Add BLAST›292

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi241N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ03682.

Structurei

3D structure databases

ProteinModelPortaliQ03682.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi289 – 292Prevents secretion from ERPROSITE-ProRule annotation4

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q03682-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
KVQQLLKDYF DGKEPNKGVN PDEAVAFGAA VQGGILSGEG GDETKDILLL
60 70 80 90 100
DVAPLTLGIE TVGGVMTKLI PRNTVIPTKK SQVFTTYQDQ QTTVSIQVFE
110 120 130 140 150
GERSLTKDCR LLGKFDLTGI APAPRGTPQI EVTFEVDANG ILNVKAEDKG
160 170 180 190 200
TGKSEKITIT NDKGRLSQEE IERMVREAEE FAEEDKKVKE RIDARNSLET
210 220 230 240 250
YVYNMKNQIN DKDKLADKLE SDEKEKIETA TKEALEWLDD NQSAEKEDYE
260 270 280 290
EKLKEVEAVC NPIITAVYQR SGGAPGGGSS EEEEEEDGHD EL
Length:292
Mass (Da):32,260
Last modified:February 1, 1995 - v1
Checksum:i6E7A4F5107C6E2D5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60059 mRNA. Translation: CAA42661.1.
PIRiPQ0262. S21878.
UniGeneiNta.9843.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60059 mRNA. Translation: CAA42661.1.
PIRiPQ0262. S21878.
UniGeneiNta.9843.

3D structure databases

ProteinModelPortaliQ03682.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ03682.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBIP2_TOBAC
AccessioniPrimary (citable) accession number: Q03682
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 5, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.