Reviewed, UniProtKB/Swiss-Prot Q03652 (DML1_YEAST)

Names and origin

Protein names

Recommended name:
    Protein DML1
Alternative name(s):
    Drosophila melanogaster misato-like protein 1

Gene names

Name:	DML1
Ordered Locus Names:	YMR211W
ORF Names:	YM8261.05

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance. Ref.2
Subcellular location	Mitochondrion. Ref.2 Ref.3
Sequence similarities	Belongs to the misato family.

Ontologies

Keywords
Cellular component	Mitochondrion
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mitochondrial genome maintenance Ref.2 Inferred from mutant phenotype. Source: SGD plasmid maintenance Ref.2 Inferred from mutant phenotype. Source: SGD protein polymerization Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrion Ref.3 Inferred from direct assay. Source: SGD protein complex Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
LPD1	P09624	1	EBI-27461,EBI-5940

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 475	475	Protein DML1		PRO_0000203331

Sequences

	Sequence		Length	Mass (Da)
	Q03652-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: A24CA4E6BA9DC146	FASTA	475	55,312
	10 20 30 40 50 60 MHEVVTISVS QRANHLTTQF FNIQEGYLQL SKEQQVNDSK IFLNSVVDKV SKTISYAPRA 70 80 90 100 110 120 LLWDARTGNG SLGTYQYSES QDYHFGNEDK FKEQTVIKTH PRIPKSEYQS SLDAGAPLPC 130 140 150 160 170 180 LNRENTMYWS DYSKLIYGPS SFNILRNWYH DTENPNQPDF QNLGERKFDR YSIGYDEFTE 190 200 210 220 230 240 NYLQEFFDGN LHRELEKCDT LQGFNLVSDM ESGWGGFSSA LLVELRNELP KKAVFSWGHN 250 260 270 280 290 300 EDDPFTDDFP MKRLSKKWLP IISNKLRSTI NMMQESDLYF PLYAAPGLTN WETAGKSCRI 310 320 330 340 350 360 FDSINATISQ SNLEQRKTMD YLTTAITLGY SSRNMVTGMV IGDTDYSFCS RVLPFKNSHK 370 380 390 400 410 420 PNSTHIFSKS FIDRGNQTHK HHSEPDSRSK MIEMYTHRYF PSDTIPTEFS NDREFVLELE 430 440 450 460 470 SSEKNRDIFK HWNEFVVRYF KNDSDREELK NELSDYASAY ESGWYEDEDS GDDDM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. , Skelton J., Walsh S.V., Whitehead S., Barrell B.G. Nature 387:90-93(1997) [PubMed: 9169872] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster." Gurvitz A., Hartig A., Ruis H., Hamilton B., de Couet H.G. FEMS Yeast Res. 2:123-135(2002) [PubMed: 12702300] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION.
[3]	"Assigning function to yeast proteins by integration of technologies." Hazbun T.R., Malmstroem L., Anderson S., Graczyk B.J., Fox B., Riffle M., Sundin B.A., Aranda J.D., McDonald W.H., Chiu C.-H., Snydsman B.E., Bradley P., Muller E.G.D., Fields S., Baker D., Yates J.R. III, Davis T.N. Mol. Cell 12:1353-1365(2003) [PubMed: 14690591] [Abstract] Cited for: SUBCELLULAR LOCATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z49809 Genomic DNA. Translation: CAA89926.1.
PIR	S55093.
RefSeq	NP_013938.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:1270N.
IntAct	Q03652. 6 interactions.
Genome annotation databases
Ensembl	YMR211W. Saccharomyces cerevisiae. [Contig view]
GeneID	855251.
GenomeReviews	Gene locus YMR211W in contig Z71257_GR.
KEGG	sce:YMR211W.
NMPDR	fig|4932.3.peg.4991.
Organism-specific databases
CYGD	YMR211w.
SGD	S000004824. DML1.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	Q03652.
OMA	Q03652. GWGGFSS.
Gene expression databases
GermOnline	YMR211W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR003008. Tubulin_FtsZ_GTPase. [Graphical view]
Pfam	PF00091. Tubulin. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	978825.

Entry information

Entry name

DML1_YEAST

Accession

Primary (citable) accession number: Q03652

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	June 16, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)