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Q03652

- DML1_YEAST

UniProt

Q03652 - DML1_YEAST

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Protein

Protein DML1

Gene
DML1, YMR211W, YM8261.05
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.1 Publication

GO - Biological processi

  1. mitochondrial genome maintenance Source: SGD
  2. plasmid maintenance Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-32894-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein DML1
Alternative name(s):
Drosophila melanogaster misato-like protein 1
Gene namesi
Name:DML1
Ordered Locus Names:YMR211W
ORF Names:YM8261.05
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIII

Organism-specific databases

CYGDiYMR211w.
SGDiS000004824. DML1.

Subcellular locationi

Mitochondrion 2 Publications

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Protein DML1PRO_0000203331Add
BLAST

Proteomic databases

MaxQBiQ03652.
PaxDbiQ03652.

Expressioni

Gene expression databases

GenevestigatoriQ03652.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
LPD1P096241EBI-27461,EBI-5940

Protein-protein interaction databases

BioGridi35389. 6 interactions.
DIPiDIP-1270N.
IntActiQ03652. 2 interactions.
MINTiMINT-409063.
STRINGi4932.YMR211W.

Structurei

3D structure databases

ProteinModelPortaliQ03652.

Family & Domainsi

Sequence similaritiesi

Belongs to the misato family.

Phylogenomic databases

eggNOGiNOG258372.
HOGENOMiHOG000066051.
OMAiDNGWGGF.
OrthoDBiEOG7HB5K9.

Family and domain databases

Gene3Di3.40.50.1440. 2 hits.
InterProiIPR029209. DML1/Misato_tubulin.
IPR019605. Misato_II_tubulin-like.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF10644. Misat_Tub_SegII. 1 hit.
PF14881. Tubulin_3. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 2 hits.

Sequencei

Sequence statusi: Complete.

Q03652-1 [UniParc]FASTAAdd to Basket

« Hide

MHEVVTISVS QRANHLTTQF FNIQEGYLQL SKEQQVNDSK IFLNSVVDKV    50
SKTISYAPRA LLWDARTGNG SLGTYQYSES QDYHFGNEDK FKEQTVIKTH 100
PRIPKSEYQS SLDAGAPLPC LNRENTMYWS DYSKLIYGPS SFNILRNWYH 150
DTENPNQPDF QNLGERKFDR YSIGYDEFTE NYLQEFFDGN LHRELEKCDT 200
LQGFNLVSDM ESGWGGFSSA LLVELRNELP KKAVFSWGHN EDDPFTDDFP 250
MKRLSKKWLP IISNKLRSTI NMMQESDLYF PLYAAPGLTN WETAGKSCRI 300
FDSINATISQ SNLEQRKTMD YLTTAITLGY SSRNMVTGMV IGDTDYSFCS 350
RVLPFKNSHK PNSTHIFSKS FIDRGNQTHK HHSEPDSRSK MIEMYTHRYF 400
PSDTIPTEFS NDREFVLELE SSEKNRDIFK HWNEFVVRYF KNDSDREELK 450
NELSDYASAY ESGWYEDEDS GDDDM 475
Length:475
Mass (Da):55,312
Last modified:November 1, 1997 - v1
Checksum:iA24CA4E6BA9DC146
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49809 Genomic DNA. Translation: CAA89926.1.
BK006946 Genomic DNA. Translation: DAA10110.1.
PIRiS55093.
RefSeqiNP_013938.1. NM_001182718.1.

Genome annotation databases

EnsemblFungiiYMR211W; YMR211W; YMR211W.
GeneIDi855251.
KEGGisce:YMR211W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49809 Genomic DNA. Translation: CAA89926.1 .
BK006946 Genomic DNA. Translation: DAA10110.1 .
PIRi S55093.
RefSeqi NP_013938.1. NM_001182718.1.

3D structure databases

ProteinModelPortali Q03652.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35389. 6 interactions.
DIPi DIP-1270N.
IntActi Q03652. 2 interactions.
MINTi MINT-409063.
STRINGi 4932.YMR211W.

Proteomic databases

MaxQBi Q03652.
PaxDbi Q03652.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YMR211W ; YMR211W ; YMR211W .
GeneIDi 855251.
KEGGi sce:YMR211W.

Organism-specific databases

CYGDi YMR211w.
SGDi S000004824. DML1.

Phylogenomic databases

eggNOGi NOG258372.
HOGENOMi HOG000066051.
OMAi DNGWGGF.
OrthoDBi EOG7HB5K9.

Enzyme and pathway databases

BioCyci YEAST:G3O-32894-MONOMER.

Miscellaneous databases

NextBioi 978825.
PROi Q03652.

Gene expression databases

Genevestigatori Q03652.

Family and domain databases

Gene3Di 3.40.50.1440. 2 hits.
InterProi IPR029209. DML1/Misato_tubulin.
IPR019605. Misato_II_tubulin-like.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view ]
Pfami PF10644. Misat_Tub_SegII. 1 hit.
PF14881. Tubulin_3. 1 hit.
[Graphical view ]
SUPFAMi SSF52490. SSF52490. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster."
    Gurvitz A., Hartig A., Ruis H., Hamilton B., de Couet H.G.
    FEMS Yeast Res. 2:123-135(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  4. Cited for: SUBCELLULAR LOCATION.

Entry informationi

Entry nameiDML1_YEAST
AccessioniPrimary (citable) accession number: Q03652
Secondary accession number(s): D6W036
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 11, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

External Data

Dasty 3

Similar proteinsi