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Q03652 (DML1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein DML1
Alternative name(s):
Drosophila melanogaster misato-like protein 1
Gene names
Name:DML1
Ordered Locus Names:YMR211W
ORF Names:YM8261.05
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length475 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance. Ref.3

Subcellular location

Mitochondrion Ref.3 Ref.4.

Sequence similarities

Belongs to the misato family.

Ontologies

Keywords
   Cellular componentMitochondrion
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmitochondrial genome maintenance

Inferred from mutant phenotype Ref.3. Source: SGD

plasmid maintenance

Inferred from mutant phenotype Ref.3. Source: SGD

   Cellular_componentmitochondrion

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

LPD1P096241EBI-27461,EBI-5940

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 475475Protein DML1
PRO_0000203331

Sequences

Sequence LengthMass (Da)Tools
Q03652 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: A24CA4E6BA9DC146

FASTA47555,312
        10         20         30         40         50         60 
MHEVVTISVS QRANHLTTQF FNIQEGYLQL SKEQQVNDSK IFLNSVVDKV SKTISYAPRA 

        70         80         90        100        110        120 
LLWDARTGNG SLGTYQYSES QDYHFGNEDK FKEQTVIKTH PRIPKSEYQS SLDAGAPLPC 

       130        140        150        160        170        180 
LNRENTMYWS DYSKLIYGPS SFNILRNWYH DTENPNQPDF QNLGERKFDR YSIGYDEFTE 

       190        200        210        220        230        240 
NYLQEFFDGN LHRELEKCDT LQGFNLVSDM ESGWGGFSSA LLVELRNELP KKAVFSWGHN 

       250        260        270        280        290        300 
EDDPFTDDFP MKRLSKKWLP IISNKLRSTI NMMQESDLYF PLYAAPGLTN WETAGKSCRI 

       310        320        330        340        350        360 
FDSINATISQ SNLEQRKTMD YLTTAITLGY SSRNMVTGMV IGDTDYSFCS RVLPFKNSHK 

       370        380        390        400        410        420 
PNSTHIFSKS FIDRGNQTHK HHSEPDSRSK MIEMYTHRYF PSDTIPTEFS NDREFVLELE 

       430        440        450        460        470 
SSEKNRDIFK HWNEFVVRYF KNDSDREELK NELSDYASAY ESGWYEDEDS GDDDM 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII."
Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. expand/collapse author list , Skelton J., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster."
Gurvitz A., Hartig A., Ruis H., Hamilton B., de Couet H.G.
FEMS Yeast Res. 2:123-135(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.
[4]"Assigning function to yeast proteins by integration of technologies."
Hazbun T.R., Malmstroem L., Anderson S., Graczyk B.J., Fox B., Riffle M., Sundin B.A., Aranda J.D., McDonald W.H., Chiu C.-H., Snydsman B.E., Bradley P., Muller E.G.D., Fields S., Baker D., Yates J.R. III, Davis T.N.
Mol. Cell 12:1353-1365(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49809 Genomic DNA. Translation: CAA89926.1.
BK006946 Genomic DNA. Translation: DAA10110.1.
PIRS55093.
RefSeqNP_013938.1. NM_001182718.1.

3D structure databases

ProteinModelPortalQ03652.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35389. 6 interactions.
DIPDIP-1270N.
IntActQ03652. 2 interactions.
MINTMINT-409063.
STRING4932.YMR211W.

Proteomic databases

MaxQBQ03652.
PaxDbQ03652.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYMR211W; YMR211W; YMR211W.
GeneID855251.
KEGGsce:YMR211W.

Organism-specific databases

CYGDYMR211w.
SGDS000004824. DML1.

Phylogenomic databases

eggNOGNOG258372.
HOGENOMHOG000066051.
OMADNGWGGF.
OrthoDBEOG7HB5K9.

Enzyme and pathway databases

BioCycYEAST:G3O-32894-MONOMER.

Gene expression databases

GenevestigatorQ03652.

Family and domain databases

Gene3D3.40.50.1440. 2 hits.
InterProIPR029209. DML1/Misato_tubulin.
IPR019605. Misato_II_tubulin-like.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamPF10644. Misat_Tub_SegII. 1 hit.
PF14881. Tubulin_3. 1 hit.
[Graphical view]
SUPFAMSSF52490. SSF52490. 2 hits.
ProtoNetSearch...

Other

NextBio978825.
PROQ03652.

Entry information

Entry nameDML1_YEAST
AccessionPrimary (citable) accession number: Q03652
Secondary accession number(s): D6W036
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 11, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families