Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein DML1

Gene

DML1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.1 Publication

GO - Molecular functioni

GO - Biological processi

  • mitochondrial genome maintenance Source: SGD
  • plasmid maintenance Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-32894-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein DML1
Alternative name(s):
Drosophila melanogaster misato-like protein 1
Gene namesi
Name:DML1
Ordered Locus Names:YMR211W
ORF Names:YM8261.05
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome XIII

Organism-specific databases

CYGDiYMR211w.
EuPathDBiFungiDB:YMR211W.
SGDiS000004824. DML1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Protein DML1PRO_0000203331Add
BLAST

Proteomic databases

MaxQBiQ03652.
PaxDbiQ03652.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
LPD1P096241EBI-27461,EBI-5940

Protein-protein interaction databases

BioGridi35389. 6 interactions.
DIPiDIP-1270N.
IntActiQ03652. 2 interactions.
MINTiMINT-409063.

Structurei

3D structure databases

ProteinModelPortaliQ03652.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the misato family.Curated

Phylogenomic databases

eggNOGiNOG258372.
HOGENOMiHOG000066051.
InParanoidiQ03652.
OMAiDNGWGGF.
OrthoDBiEOG7HB5K9.

Family and domain databases

Gene3Di3.40.50.1440. 2 hits.
InterProiIPR029209. DML1/Misato_tubulin.
IPR019605. Misato_II_tubulin-like.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF10644. Misat_Tub_SegII. 1 hit.
PF14881. Tubulin_3. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 2 hits.

Sequencei

Sequence statusi: Complete.

Q03652-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHEVVTISVS QRANHLTTQF FNIQEGYLQL SKEQQVNDSK IFLNSVVDKV
60 70 80 90 100
SKTISYAPRA LLWDARTGNG SLGTYQYSES QDYHFGNEDK FKEQTVIKTH
110 120 130 140 150
PRIPKSEYQS SLDAGAPLPC LNRENTMYWS DYSKLIYGPS SFNILRNWYH
160 170 180 190 200
DTENPNQPDF QNLGERKFDR YSIGYDEFTE NYLQEFFDGN LHRELEKCDT
210 220 230 240 250
LQGFNLVSDM ESGWGGFSSA LLVELRNELP KKAVFSWGHN EDDPFTDDFP
260 270 280 290 300
MKRLSKKWLP IISNKLRSTI NMMQESDLYF PLYAAPGLTN WETAGKSCRI
310 320 330 340 350
FDSINATISQ SNLEQRKTMD YLTTAITLGY SSRNMVTGMV IGDTDYSFCS
360 370 380 390 400
RVLPFKNSHK PNSTHIFSKS FIDRGNQTHK HHSEPDSRSK MIEMYTHRYF
410 420 430 440 450
PSDTIPTEFS NDREFVLELE SSEKNRDIFK HWNEFVVRYF KNDSDREELK
460 470
NELSDYASAY ESGWYEDEDS GDDDM
Length:475
Mass (Da):55,312
Last modified:November 1, 1997 - v1
Checksum:iA24CA4E6BA9DC146
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49809 Genomic DNA. Translation: CAA89926.1.
BK006946 Genomic DNA. Translation: DAA10110.1.
PIRiS55093.
RefSeqiNP_013938.1. NM_001182718.1.

Genome annotation databases

EnsemblFungiiYMR211W; YMR211W; YMR211W.
GeneIDi855251.
KEGGisce:YMR211W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49809 Genomic DNA. Translation: CAA89926.1.
BK006946 Genomic DNA. Translation: DAA10110.1.
PIRiS55093.
RefSeqiNP_013938.1. NM_001182718.1.

3D structure databases

ProteinModelPortaliQ03652.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35389. 6 interactions.
DIPiDIP-1270N.
IntActiQ03652. 2 interactions.
MINTiMINT-409063.

Proteomic databases

MaxQBiQ03652.
PaxDbiQ03652.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYMR211W; YMR211W; YMR211W.
GeneIDi855251.
KEGGisce:YMR211W.

Organism-specific databases

CYGDiYMR211w.
EuPathDBiFungiDB:YMR211W.
SGDiS000004824. DML1.

Phylogenomic databases

eggNOGiNOG258372.
HOGENOMiHOG000066051.
InParanoidiQ03652.
OMAiDNGWGGF.
OrthoDBiEOG7HB5K9.

Enzyme and pathway databases

BioCyciYEAST:G3O-32894-MONOMER.

Miscellaneous databases

NextBioi978825.
PROiQ03652.

Family and domain databases

Gene3Di3.40.50.1440. 2 hits.
InterProiIPR029209. DML1/Misato_tubulin.
IPR019605. Misato_II_tubulin-like.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF10644. Misat_Tub_SegII. 1 hit.
PF14881. Tubulin_3. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster."
    Gurvitz A., Hartig A., Ruis H., Hamilton B., de Couet H.G.
    FEMS Yeast Res. 2:123-135(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  4. Cited for: SUBCELLULAR LOCATION.

Entry informationi

Entry nameiDML1_YEAST
AccessioniPrimary (citable) accession number: Q03652
Secondary accession number(s): D6W036
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 22, 2015
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.