Transport protein particle 18 kDa subunit - Saccharomyces cerevisiae (Baker's yeast)

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Reviewed, UniProtKB/Swiss-Prot Q03630 (BET5_YEAST)

Last modified November 24, 2009. Version 75. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein names

Recommended name:
Transport protein particle 18 kDa subunit
Short name=TRAPP 18 kDa subunit

Gene names

Name:	BET5
Ordered Locus Names:	YML077W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

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General annotation (Comments)

Function	Component of the TRAPP I and TRAPP II complexes. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II seems to play a role in intra-Golgi transport. Ref.3 Ref.5
Subunit structure	Part of the multisubunit TRAPP (transport protein particle) II complex composed of BET3, BET5, TRS20, TRS23, TRS31, TRS33, TRS65, TRS85, TRS120 and TRS130. Part of the multisubunit TRAPP (transport protein particle) I complex composed of BET3, BET5, TRS20, TRS23, TRS31, TRS33 and TRS85.
Subcellular location	Golgi apparatus › cis-Golgi network. Endoplasmic reticulum Probable.
Sequence similarities	Belongs to the TRAPP small subunits family. BET5 subfamily.

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Ontologies

Keywords
Biological process	ER-Golgi transport Transport
Cellular component	Endoplasmic reticulum Golgi apparatus
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	ER to Golgi vesicle-mediated transport Inferred from mutant phenotype. Source: SGD
Cellular component	TRAPP complex Inferred from direct assay. Source: SGD endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

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Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 159

159

Transport protein particle 18 kDa subunit

PRO_0000211565

Secondary structure

159

Helix Strand Turn

Details...

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Sequences

Sequence

Length

Mass (Da)

Tools

Q03630-1 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 4821217270F516E9
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FASTA

159

18,434

        10         20         30         40         50         60 
MGIYSFWIFD RHCNCIFDRE WTLASNSASG TINSKQNEED AKLLYGMIFS LRSITQKLSK 

        70         80         90        100        110        120 
GSVKNDIRSI STGKYRVHTY CTASGLWFVL LSDFKQQSYT QVLQYIYSHI YVKYVSNNLL 

       130        140        150 
SPYDFAENEN EMRGQGTRKI TNRNFISVLE SFLAPMVNQ

« Hide

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. Barrell B.G. Nature 387:90-93(1997) [PubMed: 9169872] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"A high copy suppressor screen reveals genetic interactions between BET3 and a new gene. Evidence for a novel complex in ER-to-Golgi transport." Jiang Y., Scarpa A., Zhang L., Stone S., Feliciano E., Ferro-Novick S. Genetics 149:833-841(1998) [PubMed: 9611195] [Abstract] Cited for: FUNCTION.
[4]	"TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion." Sacher M., Jiang Y., Barrowman J., Scarpa A., Burston J., Zhang L., Schieltz D., Yates J.R. III, Abeliovich H., Ferro-Novick S. EMBO J. 17:2494-2503(1998) [PubMed: 9564032] [Abstract] Cited for: IDENTIFICATION IN THE TRAPP II COMPLEX.
[5]	"TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport." Sacher M., Barrowman J., Wang W., Horecka J., Zhang Y., Pypaert M., Ferro-Novick S. Mol. Cell 7:433-442(2001) [PubMed: 11239471] [Abstract] Cited for: FUNCTION OF THE TRAPP II COMPLEX, IDENTIFICATION IN THE TRAPP II COMPLEX, FUNCTION OF THE TRAPP I COMPLEX, IDENTIFICATION IN THE TRAPP I COMPLEX, SUBCELLULAR LOCATION.
+	Additional computationally mapped references.

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Cross-references

Sequence databases

Z46373 Genomic DNA. Translation: CAA86501.1.
AY557760 Genomic DNA. Translation: AAS56086.1.

PIR

S48820.

RefSeq

NP_013634.1.

3D structure databases

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3CUE	X-ray	3.70	C/I/O/U	1-159	[»]

ModBase

Search...

Protein-protein interaction databases

DIP

DIP:4528N.

IntAct

Q03630. 8 interactions.

STRING

Q03630.

Genome annotation databases

Ensembl

YML077W; YML077W; YML077W; Saccharomyces cerevisiae. [Genome view]

GeneID

854898.

KEGG

sce:YML077W.

NMPDR

fig|4932.3.peg.4671.

Organism-specific databases

CYGD

YML077w.

SGD

S000004542. BET5.

Phylogenomic databases

HOGENOM

Q03630.

OMA

SGTINSK

OrthoDB

EOG9VMGXP

Gene expression databases

ArrayExpress

Q03630.

Genevestigator

Q03630.

GermOnline

YML077W. Saccharomyces cerevisiae.

Family and domain databases

InterPro

IPR011012. Longin-like.
IPR007233. Sybindin.
[Graphical view]

PANTHER

PTHR23249. Sybindin. 1 hit.

Pfam

PF04099. Sybindin. 1 hit.
[Graphical view]

ProtoNet

Search...

Other Resources

NextBio

977870.

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Entry information

Entry name

BET5_YEAST

Accession

Primary (citable) accession number: Q03630

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 24, 2009
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)

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