Q035P2 (Q035P2_LACC3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2 HAMAP MF_01039
Short name=BPG-dependent PGAM 2 HAMAP MF_01039
Short name=PGAM 2 HAMAP MF_01039
Short name=Phosphoglyceromutase 2 HAMAP MF_01039
Short name=dPGM 2 HAMAP MF_01039
EC=5.4.2.1 HAMAP MF_01039

Gene names

Name:	gpmA2 HAMAP MF_01039
Ordered Locus Names:	LSEI_2336

Organism

Lactobacillus casei (strain ATCC 334) [Complete proteome] [HAMAP] EMBL ABJ71080.1

Taxonomic identifier

321967 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP MF_01039

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_01039
Molecular function	Isomerase HAMAP MF_01039 EMBL ABJ71080.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity HAMAP MF_01039
	Active site	177	1	By similarity HAMAP MF_01039
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity HAMAP MF_01039

Sequences

	Sequence		Length	Mass (Da)
	Q035P2 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: B758602919167283	FASTA	223	24,808
	10 20 30 40 50 60 MVKLVLLRHG ESIANQKNTY TGWSDVGLTA EGKAQAETAG ETIASTGILF DHVHTSVLSR 70 80 90 100 110 120 AIMTAYIVQD KIGQNYLPIT KSWRLNERHY GALRGINKDL TRKLFGPDQV ASWRRSFSAH 130 140 150 160 170 180 PPLLANPSRT RRYHCYPATI IPRGESLADA SQRLLPYWTA ELAPRLLSGK NQLIVAHGST 190 200 210 220 LRALVKFMED ISDAGINKVE IGNAQPIVYT LDDKLTIMDK QTL

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000423 Genomic DNA. Translation: ABJ71080.1.
RefSeq	YP_807522.1. NC_008526.1.
3D structure databases
ProteinModelPortal	Q035P2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q035P2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4420900.
GenomeReviews	Gene locus LSEI_2336 in contig CP000423_GR.
KEGG	lca:LSEI_2336.
PATRIC	22208388. VBILacCas62221_2297.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0588.
HOGENOM	HBG658938.
OMA	ESTANRD.
PhylomeDB	Q035P2.
ProtClustDB	CLSK2318358.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
KO	K01834.
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. Pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q035P2_LACC3

Accession

Primary (citable) accession number: Q035P2

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)