Q03588 (RPOH_THEAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit H
EC=2.7.7.6

Gene names

Name:	rpoH
Ordered Locus Names:	Ta0389

Organism

Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

Taxonomic identifier

273075 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	87 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_00025
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00025
Sequence similarities	Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family.
Sequence caution	The sequence CAC11533.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 87	87	DNA-directed RNA polymerase subunit H HAMAP MF_00025		PRO_0000146106

Sequences

	Sequence		Length	Mass (Da)
	Q03588 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: 9C5B1F39ABAC6F4E	FASTA	87	9,927
	10 20 30 40 50 60 MAKFNVLDHN LVPEHHIVPE EEEKNILKEL NIEKEFLPKI SPNDPAIKAL EAVHGKIKEG 70 80 TIIKIVRKSP TMGHSVYYRV VASEVFK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of the genes encoding the subunits H, B, A' and A'' of the DNA-dependent RNA polymerase and the initiator tRNA from Thermoplasma acidophilum." Klenk H.-P., Renner O., Schwass V., Zillig W. Nucleic Acids Res. 20:5226-5226(1992) [PubMed: 1408839] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.
[2]	"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum." Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W. Nature 407:508-513(2000) [PubMed: 11029001] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X68198 Genomic DNA. Translation: CAA48279.1. AL445064 Genomic DNA. Translation: CAC11533.1. Different initiation.
PIR	S26721.
RefSeq	NP_393869.1. NC_002578.1.
3D structure databases
ProteinModelPortal	Q03588.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1456005.
GenomeReviews	Gene locus Ta0389 in contig AL139299_GR.
KEGG	tac:Ta0389.
NMPDR	fig|273075.1.peg.391.
Phylogenomic databases
HOGENOM	HBG496846.
OMA	EHELVPK.
ProtClustDB	PRK09570.
Enzyme and pathway databases
BioCyc	TACI273075:TA0389-MONOMER.
Family and domain databases
HAMAP	MF_00025. RNApol_arch_H. [Tree]
InterPro	IPR020609. DNA-dir_RNA_pol_subH/Rpb5_arc. IPR000783. RNA_pol_subH/Rpb5_C. IPR020608. RNA_pol_subH/Rpb5_CS. [Graphical view]
Gene3D	G3DSA:3.90.940.20. RNApol_RPB5. 1 hit.
KO	K03053.
Pfam	PF01191. RNA_pol_Rpb5_C. 1 hit. [Graphical view]
ProDom	PD005155. RNA_pol_subH/Rpb5_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF55287. RNApol_RPB5_like. 1 hit.
PROSITE	PS01110. RNA_POL_H_23KD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPOH_THEAC

Accession

Primary (citable) accession number: Q03588

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	November 16, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program