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Reviewed, UniProtKB/Swiss-Prot Q03577 (SYDC_CAEEL)

Last modified February 9, 2010. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Aspartyl-tRNA synthetase, cytoplasmic
    EC=6.1.1.12
Alternative name(s):
    Aspartate--tRNA ligase
      Short name=AspRS
Gene names
Name: drs-1
ORF Names: B0464.1
OrganismCaenorhabditis elegans [Complete proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length531 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Catalytic activity

ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 531531Aspartyl-tRNA synthetase, cytoplasmic
PRO_0000111013

Sequences

Sequence LengthMass (Da)Tools
Q03577-1 [UniParc].

Last modified October 1, 1993. Version 1.
Checksum: 094E3207DC102733

FASTA53159,939
        10         20         30         40         50         60 
MADAAEGEQP KLSKKELNKL ARKAKKDEKA GEKGGNQQQA AAMDQEDASK DFYGSYGLVN 

        70         80         90        100        110        120 
SKEKKVLNFL KVKEINVSNA TKDVWVRGRI HTTRSKGKNC FLVLRQGVYT VQVAMFMNEK 

       130        140        150        160        170        180 
ISKQMLKFVS SISKESIVDV YATINKVDNP IESCTQKDVE LLAQQVFVVS TSAPKLPLQI 

       190        200        210        220        230        240 
EDASRRAPTD EEKASEQENQ LAVVNLDTRL DNRVIDLRTP TSHAIFRIQA GICNQFRNIL 

       250        260        270        280        290        300 
DVRGFVEIMA PKIISAPSEG GANVFEVSYF KGSAYLAQSP QLYKQMAIAG DFEKVYTIGP 

       310        320        330        340        350        360 
VFRAEDSNTH RHMTEFVGLD LEMAFNFHYH EVMETIAEVL TQMFKGLQQN YQDEIAAVGN 

       370        380        390        400        410        420 
QYPAEPFQFC EPPLILKYPD AITLLRENGI EIGDEDDLST PVEKFLGKLV KEKYSTDFYV 

       430        440        450        460        470        480 
LDKFPLSVRP FYTMPDAHDE RYSNSYDMFM RGEEILSGAQ RIHDADMLVE RAKHHQVDLA 

       490        500        510        520        530 
KIQSYIDSFK YGCPPHAGGG IGLERVTMLF LGLHNIRLAS LFPRDPKRLT P 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z19152 Genomic DNA. Translation: CAA79536.1.
PIRS28278.
RefSeqNP_499089.1.
UniGeneCel.7882

3D structure databases

SMRQ03577. Positions 46-531.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ03577.

Genome annotation databases

EnsemblB0464.1.1; B0464.1.1; B0464.1; Caenorhabditis elegans. [Genome view]
B0464.1.2; B0464.1.2; B0464.1; Caenorhabditis elegans. [Genome view]
GeneID176334.
KEGGcel:B0464.1.
UCSCB0464.1.1. c. elegans.

Organism-specific databases

CTD176334.
WormBaseWBGene00001094. drs-1.
WormPepB0464.1. CE00015. [WorfDB]

Phylogenomic databases

eggNOGmeNOG04046.
HOGENOMHBG745843.
InParanoidQ03577.
OMARNPKQSN.
PhylomeDBQ03577.

Enzyme and pathway databases

BRENDA6.1.1.12. 672.

Gene expression databases

ArrayExpressQ03577.

Family and domain databases

InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II_cons-dom.
IPR002312. Asp-tRNA-synth_IIb.
IPR004523. Asp-tRNA-synth_IIb_arc/euk.
IPR012340. NA-bd_OB-fold.
IPR016027. NA-bd_OB-fold-like.
IPR004365. NA_bd_OB_tRNA-helicase.
[Graphical view]
Gene3DG3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
PANTHERPTHR22594. aa-tRNA-synt_II. 1 hit.
PfamPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR01042. TRNASYNTHASP.
TIGRFAMsTIGR00458. aspS_arch. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio892140.

Entry information

Entry nameSYDC_CAEEL
AccessionPrimary (citable) accession number: Q03577
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: February 9, 2010
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectCaenorhabditis annotation project

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents