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Protein

Uncharacterized protein RSN1

Gene

RSN1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Acts as an osmosensitive calcium-permeable cation channel.By similarity

GO - Biological processi

  • Golgi to plasma membrane transport Source: SGD
  • ion transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ion channel

Keywords - Biological processi

Ion transport, Transport

Keywords - Ligandi

Calcium

Enzyme and pathway databases

BioCyciYEAST:G3O-32940-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein RSN1
Alternative name(s):
Rescuer of SRO7 at high Nacl protein 1
Gene namesi
Name:RSN1
Ordered Locus Names:YMR266W
ORF Names:YM8156.08
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR266W.
SGDiS000004879. RSN1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321HelicalSequence analysisAdd
BLAST
Transmembranei103 – 12321HelicalSequence analysisAdd
BLAST
Transmembranei148 – 16821HelicalSequence analysisAdd
BLAST
Transmembranei392 – 41221HelicalSequence analysisAdd
BLAST
Transmembranei435 – 45521HelicalSequence analysisAdd
BLAST
Transmembranei481 – 50121HelicalSequence analysisAdd
BLAST
Transmembranei540 – 56021HelicalSequence analysisAdd
BLAST
Transmembranei575 – 59521HelicalSequence analysisAdd
BLAST
Transmembranei599 – 61921HelicalSequence analysisAdd
BLAST
Transmembranei642 – 66221HelicalSequence analysisAdd
BLAST
Transmembranei666 – 68621HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • intracellular Source: GOC
  • membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 953953Uncharacterized protein RSN1PRO_0000203348Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei949 – 9491PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ03516.

PTM databases

iPTMnetiQ03516.

Interactioni

Protein-protein interaction databases

BioGridi35444. 21 interactions.
DIPiDIP-6549N.
IntActiQ03516. 3 interactions.
MINTiMINT-691842.

Structurei

3D structure databases

ProteinModelPortaliQ03516.
SMRiQ03516. Positions 189-226.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000068232.
HOGENOMiHOG000161488.
InParanoidiQ03516.
OMAiQAYFAFQ.
OrthoDBiEOG092C0KRF.

Family and domain databases

InterProiIPR032880. Csc1_N.
IPR027815. PHM7_cyt.
IPR022257. PHM7_ext.
IPR003864. RSN1_7TM.
[Graphical view]
PfamiPF14703. PHM7_cyt. 1 hit.
PF12621. PHM7_ext. 1 hit.
PF02714. RSN1_7TM. 1 hit.
PF13967. RSN1_TM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q03516-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSTNSTNST TTATSTNTST QQVVTSLVSN GTIFGVFVIA FLILRIKLKR
60 70 80 90 100
IYEPKSSFNL INEEKKPEPL PQGVWQWLKP LLKKSDNFVI QQAGLDGYFF
110 120 130 140 150
LRYLFIIAIY CAVSMSYIFP ILLSINASNG NHESGLNQLA YQNVKHRGRY
160 170 180 190 200
FAHVFCGWIF FWGFLYIIYR ELYFYTSMKQ AVLASPRYAK KLSSRTVLFQ
210 220 230 240 250
TVPKQYLSEE EFSKLFDGVK RVWIARGSGS IEAMVKARDN MAIQLEGAET
260 270 280 290 300
KYLKAALKKI KKLNKKSPQL SVSDNIAEYV PDKKRPHHKI NKVAKFFFGK
310 320 330 340 350
KVDTISYIKE ELPKLNQKVK ALQEDHENSS PFNSVFVEFE SQYQAQVAAQ
360 370 380 390 400
ITTYHAPLFM TPVYIGIEPS DVVWFNLRMF WWERLGREVS AVSAIVALVI
410 420 430 440 450
LWAFPVAFVG MISNITSLTN EVKWLKFIYK LPKQLLGLLT SLAPTVALAV
460 470 480 490 500
LMSFLPKFIR GMAITQGAPS KQNVEYFTQQ AYFAFQVIQV FLVTTLSSAA
510 520 530 540 550
TSTVTEIVKE PTKAMDLLAS NLPKASNFFM SYVILQGLSI SSGALLQIVP
560 570 580 590 600
LILFYVLGAF LDGTVRKKWN RFCGLSSMQW GTAFPVYTNL AVITFSYSII
610 620 630 640 650
SPLILLFAAV AFFLLYIAYL YNLTYVYQES PDARGIYYPR ALFQTIVGIY
660 670 680 690 700
IGQICLLGLF AVGKGWGPIV LQVIGICVTV LIHLHLSAAF DHLSKVIPVD
710 720 730 740 750
TMKPLDGVSD TPSFKNIYKG IESTKVKKNT FGANIDMDGI KELPEFPIKK
760 770 780 790 800
YHKRSESVTE QQVENSIFSE NTFEYQFNPA NEANADGHAI NAENLIEDVP
810 820 830 840 850
LLADGDTMKI PPAPWWKRFL KPHIYYSYKA VKSRLPEIYG LVDPDERVND
860 870 880 890 900
FDISHAYDYP AVSAQCPELW IPRDPFGFSK LLISDVSGVV EMNDENATID
910 920 930 940 950
ENLKFTLRDV PPPYNDVKDE ANGEANGEFD TASKENNPFA DPKYKEEESR

SAV
Length:953
Mass (Da):107,673
Last modified:November 1, 1997 - v1
Checksum:iF6F7BA2B3F3AD44B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49260 Genomic DNA. Translation: CAA89249.1.
BK006946 Genomic DNA. Translation: DAA10166.1.
PIRiS54478.
RefSeqiNP_013993.1. NM_001182773.1.

Genome annotation databases

EnsemblFungiiYMR266W; YMR266W; YMR266W.
GeneIDi855308.
KEGGisce:YMR266W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49260 Genomic DNA. Translation: CAA89249.1.
BK006946 Genomic DNA. Translation: DAA10166.1.
PIRiS54478.
RefSeqiNP_013993.1. NM_001182773.1.

3D structure databases

ProteinModelPortaliQ03516.
SMRiQ03516. Positions 189-226.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35444. 21 interactions.
DIPiDIP-6549N.
IntActiQ03516. 3 interactions.
MINTiMINT-691842.

PTM databases

iPTMnetiQ03516.

Proteomic databases

MaxQBiQ03516.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYMR266W; YMR266W; YMR266W.
GeneIDi855308.
KEGGisce:YMR266W.

Organism-specific databases

EuPathDBiFungiDB:YMR266W.
SGDiS000004879. RSN1.

Phylogenomic databases

GeneTreeiENSGT00530000068232.
HOGENOMiHOG000161488.
InParanoidiQ03516.
OMAiQAYFAFQ.
OrthoDBiEOG092C0KRF.

Enzyme and pathway databases

BioCyciYEAST:G3O-32940-MONOMER.

Miscellaneous databases

PROiQ03516.

Family and domain databases

InterProiIPR032880. Csc1_N.
IPR027815. PHM7_cyt.
IPR022257. PHM7_ext.
IPR003864. RSN1_7TM.
[Graphical view]
PfamiPF14703. PHM7_cyt. 1 hit.
PF12621. PHM7_ext. 1 hit.
PF02714. RSN1_7TM. 1 hit.
PF13967. RSN1_TM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRSN1_YEAST
AccessioniPrimary (citable) accession number: Q03516
Secondary accession number(s): D6W092
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: September 7, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.