Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q03506

- BGLA_BACCI

UniProt

Q03506 - BGLA_BACCI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Beta-glucosidase

Gene

bglA

Organism
Bacillus circulans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei166 – 1661Proton donorSequence Analysis
Active sitei355 – 3551NucleophilePROSITE-ProRule annotation

GO - Molecular functioni

  1. beta-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase (EC:3.2.1.21)
Alternative name(s):
Amygdalase
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
Gene namesi
Name:bglA
OrganismiBacillus circulans
Taxonomic identifieri1397 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 450449Beta-glucosidasePRO_0000063870Add
BLAST

Interactioni

Protein-protein interaction databases

MINTiMINT-8328760.

Structurei

Secondary structure

1
450
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 53Combined sources
Beta strandi11 – 155Combined sources
Helixi18 – 214Combined sources
Helixi34 – 407Combined sources
Turni42 – 443Combined sources
Helixi46 – 483Combined sources
Turni51 – 555Combined sources
Helixi61 – 7111Combined sources
Beta strandi74 – 796Combined sources
Helixi82 – 854Combined sources
Beta strandi89 – 924Combined sources
Helixi95 – 11016Combined sources
Beta strandi114 – 1229Combined sources
Helixi126 – 1294Combined sources
Turni130 – 1323Combined sources
Helixi133 – 1353Combined sources
Helixi138 – 15417Combined sources
Turni155 – 1573Combined sources
Beta strandi160 – 1656Combined sources
Helixi167 – 1759Combined sources
Helixi187 – 21024Combined sources
Beta strandi215 – 2206Combined sources
Beta strandi225 – 2317Combined sources
Helixi233 – 24412Combined sources
Turni245 – 2473Combined sources
Helixi248 – 2558Combined sources
Helixi261 – 2699Combined sources
Helixi280 – 2845Combined sources
Beta strandi289 – 2946Combined sources
Beta strandi298 – 3036Combined sources
Helixi307 – 3093Combined sources
Turni310 – 3134Combined sources
Beta strandi314 – 3163Combined sources
Helixi333 – 34513Combined sources
Beta strandi351 – 3555Combined sources
Helixi373 – 39119Combined sources
Beta strandi396 – 4027Combined sources
Helixi410 – 4123Combined sources
Beta strandi420 – 4245Combined sources
Turni425 – 4284Combined sources
Beta strandi429 – 4324Combined sources
Helixi434 – 44512Combined sources
Beta strandi446 – 4494Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1QOXX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P2-450[»]
ProteinModelPortaliQ03506.
SMRiQ03506. Positions 2-450.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ03506.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.Curated

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR017736. Glyco_hydro_1_beta-glucosidase.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
TIGRFAMsiTIGR03356. BGL. 1 hit.
PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q03506-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIHMFPSDF KWGVATAAYQ IEGAYNEDGR GMSIWDTFAH TPGKVKNGDN
60 70 80 90 100
GNVACDSYHR VEEDVQLLKD LGVKVYRFSI SWPRVLPQGT GEVNRAGLDY
110 120 130 140 150
YHRLVDELLA NGIEPFCTLY HWDLPQALQD QGGWGSRITI DAFAEYAELM
160 170 180 190 200
FKELGGKIKQ WITFNEPWCM AFLSNYLGVH APGNKDLQLA IDVSHHLLVA
210 220 230 240 250
HGRAVTLFRE LGISGEIGIA PNTSWAVPYR RTKEDMEACL RVNGWSGDWY
260 270 280 290 300
LDPIYFGEYP KFMLDWYENL GYKPPIVDGD MELIHQPIDF IGINYYTSSM
310 320 330 340 350
NRYNPGEAGG MLSSEAISMG APKTDIGWEI YAEGLYDLLR YTADKYGNPT
360 370 380 390 400
LYITENGACY NDGLSLDGRI HDQRRIDYLA MHLIQASRAI EDGINLKGYM
410 420 430 440 450
EWSLMDNFEW AEGYGMRFGL VHVDYDTLVR TPKDSFYWYK GVISRGWLDL
Length:450
Mass (Da):51,303
Last modified:January 23, 2007 - v3
Checksum:iC52C1DB233B72790
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M96979 Genomic DNA. Translation: AAA22266.1.
PIRiA48969.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M96979 Genomic DNA. Translation: AAA22266.1 .
PIRi A48969.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1QOX X-ray 2.70 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P 2-450 [» ]
ProteinModelPortali Q03506.
SMRi Q03506. Positions 2-450.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-8328760.

Protein family/group databases

CAZyi GH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei Q03506.

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR017736. Glyco_hydro_1_beta-glucosidase.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
PANTHERi PTHR10353. PTHR10353. 1 hit.
Pfami PF00232. Glyco_hydro_1. 1 hit.
[Graphical view ]
PRINTSi PR00131. GLHYDRLASE1.
SUPFAMi SSF51445. SSF51445. 1 hit.
TIGRFAMsi TIGR03356. BGL. 1 hit.
PROSITEi PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Purification, characterization, gene cloning, and sequencing of a new beta-glucosidase from Bacillus circulans subsp. alkalophilus."
    Paavilainen S.K., Hellman J., Korpela T.
    Appl. Environ. Microbiol. 59:927-932(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-29.
    Strain: ATCC 21783 / subsp. Alkalophilus.

Entry informationi

Entry nameiBGLA_BACCI
AccessioniPrimary (citable) accession number: Q03506
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: January 23, 2007
Last modified: November 26, 2014
This is version 86 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3