Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q03506

- BGLA_BACCI

UniProt

Q03506 - BGLA_BACCI

Protein

Beta-glucosidase

Gene

bglA

Organism
Bacillus circulans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei166 – 1661Proton donorSequence Analysis
    Active sitei355 – 3551NucleophilePROSITE-ProRule annotation

    GO - Molecular functioni

    1. beta-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Protein family/group databases

    CAZyiGH1. Glycoside Hydrolase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-glucosidase (EC:3.2.1.21)
    Alternative name(s):
    Amygdalase
    Beta-D-glucoside glucohydrolase
    Cellobiase
    Gentiobiase
    Gene namesi
    Name:bglA
    OrganismiBacillus circulans
    Taxonomic identifieri1397 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 450449Beta-glucosidasePRO_0000063870Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-8328760.

    Structurei

    Secondary structure

    1
    450
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi3 – 53
    Beta strandi11 – 155
    Helixi18 – 214
    Helixi34 – 407
    Turni42 – 443
    Helixi46 – 483
    Turni51 – 555
    Helixi61 – 7111
    Beta strandi74 – 796
    Helixi82 – 854
    Beta strandi89 – 924
    Helixi95 – 11016
    Beta strandi114 – 1229
    Helixi126 – 1294
    Turni130 – 1323
    Helixi133 – 1353
    Helixi138 – 15417
    Turni155 – 1573
    Beta strandi160 – 1656
    Helixi167 – 1759
    Helixi187 – 21024
    Beta strandi215 – 2206
    Beta strandi225 – 2317
    Helixi233 – 24412
    Turni245 – 2473
    Helixi248 – 2558
    Helixi261 – 2699
    Helixi280 – 2845
    Beta strandi289 – 2946
    Beta strandi298 – 3036
    Helixi307 – 3093
    Turni310 – 3134
    Beta strandi314 – 3163
    Helixi333 – 34513
    Beta strandi351 – 3555
    Helixi373 – 39119
    Beta strandi396 – 4027
    Helixi410 – 4123
    Beta strandi420 – 4245
    Turni425 – 4284
    Beta strandi429 – 4324
    Helixi434 – 44512
    Beta strandi446 – 4494

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1QOXX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P2-450[»]
    ProteinModelPortaliQ03506.
    SMRiQ03506. Positions 2-450.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ03506.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 1 family.Curated

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001360. Glyco_hydro_1.
    IPR018120. Glyco_hydro_1_AS.
    IPR017736. Glyco_hydro_1_beta-glucosidase.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR10353. PTHR10353. 1 hit.
    PfamiPF00232. Glyco_hydro_1. 1 hit.
    [Graphical view]
    PRINTSiPR00131. GLHYDRLASE1.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    TIGRFAMsiTIGR03356. BGL. 1 hit.
    PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
    PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q03506-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSIHMFPSDF KWGVATAAYQ IEGAYNEDGR GMSIWDTFAH TPGKVKNGDN    50
    GNVACDSYHR VEEDVQLLKD LGVKVYRFSI SWPRVLPQGT GEVNRAGLDY 100
    YHRLVDELLA NGIEPFCTLY HWDLPQALQD QGGWGSRITI DAFAEYAELM 150
    FKELGGKIKQ WITFNEPWCM AFLSNYLGVH APGNKDLQLA IDVSHHLLVA 200
    HGRAVTLFRE LGISGEIGIA PNTSWAVPYR RTKEDMEACL RVNGWSGDWY 250
    LDPIYFGEYP KFMLDWYENL GYKPPIVDGD MELIHQPIDF IGINYYTSSM 300
    NRYNPGEAGG MLSSEAISMG APKTDIGWEI YAEGLYDLLR YTADKYGNPT 350
    LYITENGACY NDGLSLDGRI HDQRRIDYLA MHLIQASRAI EDGINLKGYM 400
    EWSLMDNFEW AEGYGMRFGL VHVDYDTLVR TPKDSFYWYK GVISRGWLDL 450
    Length:450
    Mass (Da):51,303
    Last modified:January 23, 2007 - v3
    Checksum:iC52C1DB233B72790
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M96979 Genomic DNA. Translation: AAA22266.1.
    PIRiA48969.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M96979 Genomic DNA. Translation: AAA22266.1 .
    PIRi A48969.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1QOX X-ray 2.70 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P 2-450 [» ]
    ProteinModelPortali Q03506.
    SMRi Q03506. Positions 2-450.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-8328760.

    Protein family/group databases

    CAZyi GH1. Glycoside Hydrolase Family 1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q03506.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001360. Glyco_hydro_1.
    IPR018120. Glyco_hydro_1_AS.
    IPR017736. Glyco_hydro_1_beta-glucosidase.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR10353. PTHR10353. 1 hit.
    Pfami PF00232. Glyco_hydro_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00131. GLHYDRLASE1.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    TIGRFAMsi TIGR03356. BGL. 1 hit.
    PROSITEi PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
    PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Purification, characterization, gene cloning, and sequencing of a new beta-glucosidase from Bacillus circulans subsp. alkalophilus."
      Paavilainen S.K., Hellman J., Korpela T.
      Appl. Environ. Microbiol. 59:927-932(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-29.
      Strain: ATCC 21783 / subsp. Alkalophilus.

    Entry informationi

    Entry nameiBGLA_BACCI
    AccessioniPrimary (citable) accession number: Q03506
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 85 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3