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Q03506

- BGLA_BACCI

UniProt

Q03506 - BGLA_BACCI

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Protein
Beta-glucosidase
Gene
bglA
Organism
Bacillus circulans
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei166 – 1661Proton donor Reviewed prediction
Active sitei355 – 3551Nucleophile By similarity

GO - Molecular functioni

  1. beta-glucosidase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase (EC:3.2.1.21)
Alternative name(s):
Amygdalase
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
Gene namesi
Name:bglA
OrganismiBacillus circulans
Taxonomic identifieri1397 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 450449Beta-glucosidase
PRO_0000063870Add
BLAST

Interactioni

Protein-protein interaction databases

MINTiMINT-8328760.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 53
Beta strandi11 – 155
Helixi18 – 214
Helixi34 – 407
Turni42 – 443
Helixi46 – 483
Turni51 – 555
Helixi61 – 7111
Beta strandi74 – 796
Helixi82 – 854
Beta strandi89 – 924
Helixi95 – 11016
Beta strandi114 – 1229
Helixi126 – 1294
Turni130 – 1323
Helixi133 – 1353
Helixi138 – 15417
Turni155 – 1573
Beta strandi160 – 1656
Helixi167 – 1759
Helixi187 – 21024
Beta strandi215 – 2206
Beta strandi225 – 2317
Helixi233 – 24412
Turni245 – 2473
Helixi248 – 2558
Helixi261 – 2699
Helixi280 – 2845
Beta strandi289 – 2946
Beta strandi298 – 3036
Helixi307 – 3093
Turni310 – 3134
Beta strandi314 – 3163
Helixi333 – 34513
Beta strandi351 – 3555
Helixi373 – 39119
Beta strandi396 – 4027
Helixi410 – 4123
Beta strandi420 – 4245
Turni425 – 4284
Beta strandi429 – 4324
Helixi434 – 44512
Beta strandi446 – 4494

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1QOXX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P2-450[»]
ProteinModelPortaliQ03506.
SMRiQ03506. Positions 2-450.

Miscellaneous databases

EvolutionaryTraceiQ03506.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR017736. Glyco_hydro_1_beta-glucosidase.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
TIGRFAMsiTIGR03356. BGL. 1 hit.
PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q03506-1 [UniParc]FASTAAdd to Basket

« Hide

MSIHMFPSDF KWGVATAAYQ IEGAYNEDGR GMSIWDTFAH TPGKVKNGDN    50
GNVACDSYHR VEEDVQLLKD LGVKVYRFSI SWPRVLPQGT GEVNRAGLDY 100
YHRLVDELLA NGIEPFCTLY HWDLPQALQD QGGWGSRITI DAFAEYAELM 150
FKELGGKIKQ WITFNEPWCM AFLSNYLGVH APGNKDLQLA IDVSHHLLVA 200
HGRAVTLFRE LGISGEIGIA PNTSWAVPYR RTKEDMEACL RVNGWSGDWY 250
LDPIYFGEYP KFMLDWYENL GYKPPIVDGD MELIHQPIDF IGINYYTSSM 300
NRYNPGEAGG MLSSEAISMG APKTDIGWEI YAEGLYDLLR YTADKYGNPT 350
LYITENGACY NDGLSLDGRI HDQRRIDYLA MHLIQASRAI EDGINLKGYM 400
EWSLMDNFEW AEGYGMRFGL VHVDYDTLVR TPKDSFYWYK GVISRGWLDL 450
Length:450
Mass (Da):51,303
Last modified:January 23, 2007 - v3
Checksum:iC52C1DB233B72790
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M96979 Genomic DNA. Translation: AAA22266.1.
PIRiA48969.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M96979 Genomic DNA. Translation: AAA22266.1 .
PIRi A48969.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1QOX X-ray 2.70 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P 2-450 [» ]
ProteinModelPortali Q03506.
SMRi Q03506. Positions 2-450.
ModBasei Search...

Protein-protein interaction databases

MINTi MINT-8328760.

Protein family/group databases

CAZyi GH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei Q03506.

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR017736. Glyco_hydro_1_beta-glucosidase.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
PANTHERi PTHR10353. PTHR10353. 1 hit.
Pfami PF00232. Glyco_hydro_1. 1 hit.
[Graphical view ]
PRINTSi PR00131. GLHYDRLASE1.
SUPFAMi SSF51445. SSF51445. 1 hit.
TIGRFAMsi TIGR03356. BGL. 1 hit.
PROSITEi PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Purification, characterization, gene cloning, and sequencing of a new beta-glucosidase from Bacillus circulans subsp. alkalophilus."
    Paavilainen S.K., Hellman J., Korpela T.
    Appl. Environ. Microbiol. 59:927-932(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-29.
    Strain: ATCC 21783 / subsp. Alkalophilus.

Entry informationi

Entry nameiBGLA_BACCI
AccessioniPrimary (citable) accession number: Q03506
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 84 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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