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Q034G9 (PAGL2_LACC3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
6-phospho-alpha-glucosidase 2

EC=3.2.1.122
Gene names
Ordered Locus Names:LSEI_2684
OrganismLactobacillus casei (strain ATCC 334) [Complete proteome] [HAMAP]
Taxonomic identifier321967 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length461 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Alpha-maltose 6'-phosphate + H2O = D-glucose + D-glucose 6-phosphate.

Cofactor

Binds 1 divalent metal ion per subunit. Manganese By similarity.

Binds 1 NAD+ per subunit By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 4 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4614616-phospho-alpha-glucosidase 2
PRO_0000389205

Regions

Nucleotide binding7 – 7367NAD By similarity

Sites

Active site1731Proton donor By similarity
Active site2671Proton acceptor By similarity
Metal binding1721Manganese By similarity
Metal binding2021Manganese By similarity
Binding site961Substrate By similarity
Binding site1501Substrate By similarity
Binding site2871Substrate By similarity
Site1121Increases basicity of active site Tyr By similarity

Sequences

Sequence LengthMass (Da)Tools
Q034G9 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: F96D99955DA75E84

FASTA46152,030
        10         20         30         40         50         60 
MNQNKQFSIV IAGGGSTYTA GIVMMLLENA ERFPLRALKL YDIDEERQAT IAEAIAIELK 

        70         80         90        100        110        120 
EKAPAIDFTW TTDPQTAFTD VDFCFAHIRS GGYKMREQDE KIPLKHHVVG QETCGPGGIA 

       130        140        150        160        170        180 
YGMRSIGDII ELIDFIEKYS PDCWMLNYSN PASIVAEACR RLRPDAKILN ICDMPVGTQR 

       190        200        210        220        230        240 
RMSQIIGLQP KDLEVRYFGM NHFGWWTSVK DKAGNEYLPQ IRDYVAHHGY LTQIEVDTQH 

       250        260        270        280        290        300 
MDASWQATHK KAQDLLAVDP HYLPNTYLKY YLYPDYVVAH SDPDYTRANE VEDGREKCVF 

       310        320        330        340        350        360 
SAAQKIIDAG TSDVGSFPID SHASFIVDLA CAIAFNTHER MLLIVENNGA VANIDDNIMV 

       370        380        390        400        410        420 
EVPCIVGKDG AEPLTQGKIP MFQRGMILNQ AMVEKLVVDA WINHDYQELW QALTLSKTLP 

       430        440        450        460 
SAQVAKEVLD DLIEANREYW PELKHDEHEV HLISESAVSE I 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000423 Genomic DNA. Translation: ABJ71403.1.
RefSeqYP_807845.1. NC_008526.1.

3D structure databases

ProteinModelPortalQ034G9.
SMRQ034G9. Positions 5-443.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING321967.LSEI_2684.

Protein family/group databases

CAZyGH4. Glycoside Hydrolase Family 4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ71403; ABJ71403; LSEI_2684.
GeneID4421236.
KEGGlca:LSEI_2684.
PATRIC22209078. VBILacCas62221_2628.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1486.
HOGENOMHOG000239810.
KOK01232.
OMADPQTAFT.
OrthoDBEOG632D2X.
ProtClustDBCLSK880767.

Enzyme and pathway databases

BioCycLCAS321967:GH4S-2681-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProIPR019802. GlycHydrolase_4_CS.
IPR001088. Glyco_hydro_4.
IPR022616. Glyco_hydro_4_C.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF02056. Glyco_hydro_4. 1 hit.
PF11975. Glyco_hydro_4C. 1 hit.
[Graphical view]
PRINTSPR00732. GLHYDRLASE4.
SUPFAMSSF56327. SSF56327. 1 hit.
PROSITEPS01324. GLYCOSYL_HYDROL_F4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePAGL2_LACC3
AccessionPrimary (citable) accession number: Q034G9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: November 14, 2006
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries