SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q034G9

- PAGL2_LACC3

UniProt

Q034G9 - PAGL2_LACC3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
6-phospho-alpha-glucosidase 2
Gene
LSEI_2684
Organism
Lactobacillus casei (strain ATCC 334)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Alpha-maltose 6'-phosphate + H2O = D-glucose + D-glucose 6-phosphate.

Cofactori

Binds 1 divalent metal ion per subunit. Manganese By similarity.
Binds 1 NAD+ per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei96 – 961Substrate By similarity
Sitei112 – 1121Increases basicity of active site Tyr By similarity
Binding sitei150 – 1501Substrate By similarity
Metal bindingi172 – 1721Manganese By similarity
Active sitei173 – 1731Proton donor By similarity
Metal bindingi202 – 2021Manganese By similarity
Active sitei267 – 2671Proton acceptor By similarity
Binding sitei287 – 2871Substrate By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7 – 7367NAD By similarity
Add
BLAST

GO - Molecular functioni

  1. maltose-6'-phosphate glucosidase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
  3. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism

Keywords - Ligandi

Manganese, Metal-binding, NAD

Enzyme and pathway databases

BioCyciLCAS321967:GH4S-2681-MONOMER.

Protein family/group databases

CAZyiGH4. Glycoside Hydrolase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phospho-alpha-glucosidase 2 (EC:3.2.1.122)
Gene namesi
Ordered Locus Names:LSEI_2684
OrganismiLactobacillus casei (strain ATCC 334)
Taxonomic identifieri321967 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000001651: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4614616-phospho-alpha-glucosidase 2
PRO_0000389205Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi321967.LSEI_2684.

Structurei

3D structure databases

ProteinModelPortaliQ034G9.
SMRiQ034G9. Positions 5-443.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1486.
HOGENOMiHOG000239810.
KOiK01232.
OMAiCHTRANE.
OrthoDBiEOG632D2X.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProiIPR019802. GlycHydrolase_4_CS.
IPR001088. Glyco_hydro_4.
IPR022616. Glyco_hydro_4_C.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF02056. Glyco_hydro_4. 1 hit.
PF11975. Glyco_hydro_4C. 1 hit.
[Graphical view]
PRINTSiPR00732. GLHYDRLASE4.
SUPFAMiSSF56327. SSF56327. 1 hit.
PROSITEiPS01324. GLYCOSYL_HYDROL_F4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q034G9-1 [UniParc]FASTAAdd to Basket

« Hide

MNQNKQFSIV IAGGGSTYTA GIVMMLLENA ERFPLRALKL YDIDEERQAT    50
IAEAIAIELK EKAPAIDFTW TTDPQTAFTD VDFCFAHIRS GGYKMREQDE 100
KIPLKHHVVG QETCGPGGIA YGMRSIGDII ELIDFIEKYS PDCWMLNYSN 150
PASIVAEACR RLRPDAKILN ICDMPVGTQR RMSQIIGLQP KDLEVRYFGM 200
NHFGWWTSVK DKAGNEYLPQ IRDYVAHHGY LTQIEVDTQH MDASWQATHK 250
KAQDLLAVDP HYLPNTYLKY YLYPDYVVAH SDPDYTRANE VEDGREKCVF 300
SAAQKIIDAG TSDVGSFPID SHASFIVDLA CAIAFNTHER MLLIVENNGA 350
VANIDDNIMV EVPCIVGKDG AEPLTQGKIP MFQRGMILNQ AMVEKLVVDA 400
WINHDYQELW QALTLSKTLP SAQVAKEVLD DLIEANREYW PELKHDEHEV 450
HLISESAVSE I 461
Length:461
Mass (Da):52,030
Last modified:November 14, 2006 - v1
Checksum:iF96D99955DA75E84
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000423 Genomic DNA. Translation: ABJ71403.1.
RefSeqiWP_011674973.1. NC_008526.1.
YP_807845.1. NC_008526.1.

Genome annotation databases

EnsemblBacteriaiABJ71403; ABJ71403; LSEI_2684.
GeneIDi4421236.
KEGGilca:LSEI_2684.
PATRICi22209078. VBILacCas62221_2628.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000423 Genomic DNA. Translation: ABJ71403.1 .
RefSeqi WP_011674973.1. NC_008526.1.
YP_807845.1. NC_008526.1.

3D structure databases

ProteinModelPortali Q034G9.
SMRi Q034G9. Positions 5-443.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 321967.LSEI_2684.

Protein family/group databases

CAZyi GH4. Glycoside Hydrolase Family 4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ71403 ; ABJ71403 ; LSEI_2684 .
GeneIDi 4421236.
KEGGi lca:LSEI_2684.
PATRICi 22209078. VBILacCas62221_2628.

Phylogenomic databases

eggNOGi COG1486.
HOGENOMi HOG000239810.
KOi K01232.
OMAi CHTRANE.
OrthoDBi EOG632D2X.

Enzyme and pathway databases

BioCyci LCAS321967:GH4S-2681-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProi IPR019802. GlycHydrolase_4_CS.
IPR001088. Glyco_hydro_4.
IPR022616. Glyco_hydro_4_C.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF02056. Glyco_hydro_4. 1 hit.
PF11975. Glyco_hydro_4C. 1 hit.
[Graphical view ]
PRINTSi PR00732. GLHYDRLASE4.
SUPFAMi SSF56327. SSF56327. 1 hit.
PROSITEi PS01324. GLYCOSYL_HYDROL_F4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 334.
  2. "The sim operon facilitates the transport and metabolism of sucrose isomers in Lactobacillus casei ATCC 334."
    Thompson J., Jakubovics N., Abraham B., Hess S., Pikis A.
    J. Bacteriol. 190:3362-3373(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiPAGL2_LACC3
AccessioniPrimary (citable) accession number: Q034G9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: November 14, 2006
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi