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Protein

Protein EBS1

Gene

EBS1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in telomere maintenance. May be redundant to EST1, a protein associated with the telomerase.1 Publication

GO - Molecular functioni

GO - Biological processi

  • DNA recombination Source: SGD
  • mRNA export from nucleus Source: GO_Central
  • negative regulation of translation Source: SGD
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: SGD
  • regulation of RNA stability Source: GO_Central
  • telomere maintenance via telomerase Source: GO_Central

Enzyme and pathway databases

BioCyciYEAST:G3O-29790-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein EBS1
Alternative name(s):
EST1-like BCY1 suppressor 1
Gene namesi
Name:EBS1
Ordered Locus Names:YDR206W
ORF Names:YD8142.03
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR206W
SGDiS000002614 EBS1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus, Telomere

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000869071 – 884Protein EBS1Add BLAST884

Proteomic databases

MaxQBiQ03466
PaxDbiQ03466
PRIDEiQ03466

Interactioni

Protein-protein interaction databases

BioGridi32256, 84 interactors
DIPiDIP-1297N
IntActiQ03466, 17 interactors
MINTiQ03466
STRINGi4932.YDR206W

Structurei

3D structure databases

ProteinModelPortaliQ03466
SMRiQ03466
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the EST1 family.Curated

Phylogenomic databases

GeneTreeiENSGT00530000068698
InParanoidiQ03466
KOiK11132
OMAiYPIFKWF
OrthoDBiEOG092C14B1

Family and domain databases

InterProiView protein in InterPro
IPR018834 DNA/RNA-bd_Est1-type
IPR019458 EST1
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF10374 EST1, 1 hit
PF10373 EST1_DNA_bind, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit

Sequencei

Sequence statusi: Complete.

Q03466-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPSNTQKED LPTAFNGIKS QLNSILKSNQ LFQDYALLNG FLAFVHSKLN
60 70 80 90 100
AAILTSIESQ CGKSFAADLD SFDQSSISSI LDFSWESVHY PIFKWFQMWR
110 120 130 140 150
NYILFEKENK KQQTKFIDFR KMNSKMLKFF KTVQNFYVNV INTVYKKYDI
160 170 180 190 200
SVLLPKRIIQ DLKLSDIENT TNVGDILAVK TFNSSSPLAH LIPTLFHRCL
210 220 230 240 250
LFLGTAYRYK TLLEEISNKY SISNFKKSLD FFRLASLVLP SAGETYSQAG
260 270 280 290 300
AIFLQTGNLG IAVFNFVKGM MTKMPSPVSI KNFGALMVDN KSSLNRSLHT
310 320 330 340 350
TIMNTYLQES KGPRTPAKEI LEFYFLGLFG SVWSPTSWRD DTKPNQLNNG
360 370 380 390 400
IKLRHLENAL YETMSARYLN NIKTIFHNLI ITIGGFHLLL KRRSDVSAKT
410 420 430 440 450
LKDLRSNELD YLNFAFKYIA HILNDIVKES WSENPEVSEI LGMVRIINCW
460 470 480 490 500
IKANPMVLQY SQSNLEFVNA LAYLINDIVK KKPSPSFSIT EHIPKRTYWF
510 520 530 540 550
EEDLMVKGLS FVNFQLSDFD DYEKILEMDH SLDRLIGNPP LCDKLSASSE
560 570 580 590 600
MLLRLQAVVN ISSQLLQNNN CGVEWSDNKS RYIFNKKIGF KETVKNSMKT
610 620 630 640 650
SKQSNEKAKL QRKNKPSTTN GSISMADLER QMRSSSLDSF SPTMGYSGSS
660 670 680 690 700
VPMAPDTFNV KPSGTITGNK VNVELLKIEL SGQNADGAIT NISPGYSNAA
710 720 730 740 750
ISSSNSTDES SFDLNNILSS MQQKHAEKSF AKSMQGVNEQ IPANDVCHQA
760 770 780 790 800
QRPMQGGLYS SQQPSSMSSL NSAYQNASMP PSASMVSYPY PFLNQQGQGV
810 820 830 840 850
FPPYNAQNLQ WQSEAYSLKS MNFANPTWLG DQYQTSAPSS AYAQAQRQMF
860 870 880
QQPMQQDVGK YMQFPFDAQS NTDSMRGNSR NNMF
Length:884
Mass (Da):100,000
Last modified:November 1, 1996 - v1
Checksum:i14482D64E32A1860
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68194 Genomic DNA Translation: CAA92345.1
BK006938 Genomic DNA Translation: DAA12047.1
PIRiS61569
RefSeqiNP_010492.3, NM_001180514.3

Genome annotation databases

EnsemblFungiiYDR206W; YDR206W; YDR206W
GeneIDi851787
KEGGisce:YDR206W

Similar proteinsi

Entry informationi

Entry nameiEBS1_YEAST
AccessioniPrimary (citable) accession number: Q03466
Secondary accession number(s): D6VSI7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health