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Q03466

- EBS1_YEAST

UniProt

Q03466 - EBS1_YEAST

Protein

Protein EBS1

Gene

EBS1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Involved in telomere maintenance. May be redundant to EST1, a protein associated with the telomerase.1 Publication

    GO - Biological processi

    1. DNA recombination Source: SGD
    2. negative regulation of translation Source: SGD
    3. nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-29790-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein EBS1
    Alternative name(s):
    EST1-like BCY1 suppressor 1
    Gene namesi
    Name:EBS1
    Ordered Locus Names:YDR206W
    ORF Names:YD8142.03
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome IV

    Organism-specific databases

    CYGDiYDR206w.
    SGDiS000002614. EBS1.

    Subcellular locationi

    Nucleus Curated. Chromosometelomere Curated

    GO - Cellular componenti

    1. chromosome, telomeric region Source: UniProtKB-SubCell
    2. cytoplasm Source: SGD
    3. cytoplasmic mRNA processing body Source: SGD
    4. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chromosome, Nucleus, Telomere

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 884884Protein EBS1PRO_0000086907Add
    BLAST

    Proteomic databases

    MaxQBiQ03466.
    PaxDbiQ03466.
    PeptideAtlasiQ03466.

    Expressioni

    Gene expression databases

    GenevestigatoriQ03466.

    Interactioni

    Protein-protein interaction databases

    BioGridi32256. 41 interactions.
    DIPiDIP-1297N.
    IntActiQ03466. 14 interactions.
    MINTiMINT-388876.
    STRINGi4932.YDR206W.

    Structurei

    3D structure databases

    ProteinModelPortaliQ03466.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the EST1 family.Curated

    Phylogenomic databases

    eggNOGiNOG146635.
    GeneTreeiENSGT00530000068698.
    KOiK11132.
    OMAiWIFANES.
    OrthoDBiEOG7V76G2.

    Family and domain databases

    InterProiIPR018834. DNA/RNA-bd_Est1-type.
    IPR019458. EST1.
    [Graphical view]
    PfamiPF10374. EST1. 1 hit.
    PF10373. EST1_DNA_bind. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q03466-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEPSNTQKED LPTAFNGIKS QLNSILKSNQ LFQDYALLNG FLAFVHSKLN    50
    AAILTSIESQ CGKSFAADLD SFDQSSISSI LDFSWESVHY PIFKWFQMWR 100
    NYILFEKENK KQQTKFIDFR KMNSKMLKFF KTVQNFYVNV INTVYKKYDI 150
    SVLLPKRIIQ DLKLSDIENT TNVGDILAVK TFNSSSPLAH LIPTLFHRCL 200
    LFLGTAYRYK TLLEEISNKY SISNFKKSLD FFRLASLVLP SAGETYSQAG 250
    AIFLQTGNLG IAVFNFVKGM MTKMPSPVSI KNFGALMVDN KSSLNRSLHT 300
    TIMNTYLQES KGPRTPAKEI LEFYFLGLFG SVWSPTSWRD DTKPNQLNNG 350
    IKLRHLENAL YETMSARYLN NIKTIFHNLI ITIGGFHLLL KRRSDVSAKT 400
    LKDLRSNELD YLNFAFKYIA HILNDIVKES WSENPEVSEI LGMVRIINCW 450
    IKANPMVLQY SQSNLEFVNA LAYLINDIVK KKPSPSFSIT EHIPKRTYWF 500
    EEDLMVKGLS FVNFQLSDFD DYEKILEMDH SLDRLIGNPP LCDKLSASSE 550
    MLLRLQAVVN ISSQLLQNNN CGVEWSDNKS RYIFNKKIGF KETVKNSMKT 600
    SKQSNEKAKL QRKNKPSTTN GSISMADLER QMRSSSLDSF SPTMGYSGSS 650
    VPMAPDTFNV KPSGTITGNK VNVELLKIEL SGQNADGAIT NISPGYSNAA 700
    ISSSNSTDES SFDLNNILSS MQQKHAEKSF AKSMQGVNEQ IPANDVCHQA 750
    QRPMQGGLYS SQQPSSMSSL NSAYQNASMP PSASMVSYPY PFLNQQGQGV 800
    FPPYNAQNLQ WQSEAYSLKS MNFANPTWLG DQYQTSAPSS AYAQAQRQMF 850
    QQPMQQDVGK YMQFPFDAQS NTDSMRGNSR NNMF 884
    Length:884
    Mass (Da):100,000
    Last modified:November 1, 1996 - v1
    Checksum:i14482D64E32A1860
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z68194 Genomic DNA. Translation: CAA92345.1.
    BK006938 Genomic DNA. Translation: DAA12047.1.
    PIRiS61569.
    RefSeqiNP_010492.3. NM_001180514.3.

    Genome annotation databases

    EnsemblFungiiYDR206W; YDR206W; YDR206W.
    GeneIDi851787.
    KEGGisce:YDR206W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z68194 Genomic DNA. Translation: CAA92345.1 .
    BK006938 Genomic DNA. Translation: DAA12047.1 .
    PIRi S61569.
    RefSeqi NP_010492.3. NM_001180514.3.

    3D structure databases

    ProteinModelPortali Q03466.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 32256. 41 interactions.
    DIPi DIP-1297N.
    IntActi Q03466. 14 interactions.
    MINTi MINT-388876.
    STRINGi 4932.YDR206W.

    Proteomic databases

    MaxQBi Q03466.
    PaxDbi Q03466.
    PeptideAtlasi Q03466.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YDR206W ; YDR206W ; YDR206W .
    GeneIDi 851787.
    KEGGi sce:YDR206W.

    Organism-specific databases

    CYGDi YDR206w.
    SGDi S000002614. EBS1.

    Phylogenomic databases

    eggNOGi NOG146635.
    GeneTreei ENSGT00530000068698.
    KOi K11132.
    OMAi WIFANES.
    OrthoDBi EOG7V76G2.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-29790-MONOMER.

    Miscellaneous databases

    NextBioi 969603.

    Gene expression databases

    Genevestigatori Q03466.

    Family and domain databases

    InterProi IPR018834. DNA/RNA-bd_Est1-type.
    IPR019458. EST1.
    [Graphical view ]
    Pfami PF10374. EST1. 1 hit.
    PF10373. EST1_DNA_bind. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
      Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
      , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
      Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. "The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA."
      Zhou J., Hidaka K., Futcher B.
      Mol. Cell. Biol. 20:1947-1955(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.

    Entry informationi

    Entry nameiEBS1_YEAST
    AccessioniPrimary (citable) accession number: Q03466
    Secondary accession number(s): D6VSI7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 22, 2005
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome IV
      Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

    External Data

    Dasty 3