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Q03466 (EBS1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein EBS1
Alternative name(s):
EST1-like BCY1 suppressor 1
Gene names
Name:EBS1
Ordered Locus Names:YDR206W
ORF Names:YD8142.03
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length884 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in telomere maintenance. May be redundant to EST1, a protein associated with the telomerase. Ref.3

Subcellular location

Nucleus Probable. Chromosometelomere Probable.

Sequence similarities

Belongs to the EST1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 884884Protein EBS1
PRO_0000086907

Sequences

Sequence LengthMass (Da)Tools
Q03466 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 14482D64E32A1860

FASTA884100,000
        10         20         30         40         50         60 
MEPSNTQKED LPTAFNGIKS QLNSILKSNQ LFQDYALLNG FLAFVHSKLN AAILTSIESQ 

        70         80         90        100        110        120 
CGKSFAADLD SFDQSSISSI LDFSWESVHY PIFKWFQMWR NYILFEKENK KQQTKFIDFR 

       130        140        150        160        170        180 
KMNSKMLKFF KTVQNFYVNV INTVYKKYDI SVLLPKRIIQ DLKLSDIENT TNVGDILAVK 

       190        200        210        220        230        240 
TFNSSSPLAH LIPTLFHRCL LFLGTAYRYK TLLEEISNKY SISNFKKSLD FFRLASLVLP 

       250        260        270        280        290        300 
SAGETYSQAG AIFLQTGNLG IAVFNFVKGM MTKMPSPVSI KNFGALMVDN KSSLNRSLHT 

       310        320        330        340        350        360 
TIMNTYLQES KGPRTPAKEI LEFYFLGLFG SVWSPTSWRD DTKPNQLNNG IKLRHLENAL 

       370        380        390        400        410        420 
YETMSARYLN NIKTIFHNLI ITIGGFHLLL KRRSDVSAKT LKDLRSNELD YLNFAFKYIA 

       430        440        450        460        470        480 
HILNDIVKES WSENPEVSEI LGMVRIINCW IKANPMVLQY SQSNLEFVNA LAYLINDIVK 

       490        500        510        520        530        540 
KKPSPSFSIT EHIPKRTYWF EEDLMVKGLS FVNFQLSDFD DYEKILEMDH SLDRLIGNPP 

       550        560        570        580        590        600 
LCDKLSASSE MLLRLQAVVN ISSQLLQNNN CGVEWSDNKS RYIFNKKIGF KETVKNSMKT 

       610        620        630        640        650        660 
SKQSNEKAKL QRKNKPSTTN GSISMADLER QMRSSSLDSF SPTMGYSGSS VPMAPDTFNV 

       670        680        690        700        710        720 
KPSGTITGNK VNVELLKIEL SGQNADGAIT NISPGYSNAA ISSSNSTDES SFDLNNILSS 

       730        740        750        760        770        780 
MQQKHAEKSF AKSMQGVNEQ IPANDVCHQA QRPMQGGLYS SQQPSSMSSL NSAYQNASMP 

       790        800        810        820        830        840 
PSASMVSYPY PFLNQQGQGV FPPYNAQNLQ WQSEAYSLKS MNFANPTWLG DQYQTSAPSS 

       850        860        870        880 
AYAQAQRQMF QQPMQQDVGK YMQFPFDAQS NTDSMRGNSR NNMF 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA."
Zhou J., Hidaka K., Futcher B.
Mol. Cell. Biol. 20:1947-1955(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z68194 Genomic DNA. Translation: CAA92345.1.
BK006938 Genomic DNA. Translation: DAA12047.1.
PIRS61569.
RefSeqNP_010492.3. NM_001180514.3.

3D structure databases

ProteinModelPortalQ03466.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid32256. 41 interactions.
DIPDIP-1297N.
IntActQ03466. 14 interactions.
MINTMINT-388876.
STRING4932.YDR206W.

Proteomic databases

MaxQBQ03466.
PaxDbQ03466.
PeptideAtlasQ03466.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYDR206W; YDR206W; YDR206W.
GeneID851787.
KEGGsce:YDR206W.

Organism-specific databases

CYGDYDR206w.
SGDS000002614. EBS1.

Phylogenomic databases

eggNOGNOG146635.
GeneTreeENSGT00530000068698.
KOK11132.
OMAWIFANES.
OrthoDBEOG7V76G2.

Enzyme and pathway databases

BioCycYEAST:G3O-29790-MONOMER.

Gene expression databases

GenevestigatorQ03466.

Family and domain databases

InterProIPR018834. DNA/RNA-bd_Est1-type.
IPR019458. EST1.
[Graphical view]
PfamPF10374. EST1. 1 hit.
PF10373. EST1_DNA_bind. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio969603.

Entry information

Entry nameEBS1_YEAST
AccessionPrimary (citable) accession number: Q03466
Secondary accession number(s): D6VSI7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IV

Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families