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Q03439 (COX3_BACP3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Oxidase aa(3) subunit 3
Gene names
Name:ctaE
Synonyms:caaC
OrganismBacillus sp. (strain PS3)
Taxonomic identifier2334 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length207 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 207207Cytochrome c oxidase subunit 3
PRO_0000183876

Regions

Transmembrane28 – 4821Helical; Potential
Transmembrane70 – 9021Helical; Potential
Transmembrane102 – 12221Helical; Potential
Transmembrane144 – 16421Helical; Potential
Transmembrane186 – 20621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q03439 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: F398096AF02B5621

FASTA20723,409
        10         20         30         40         50         60 
MHAEEKLTAE TFPAAPERNA TLEGKNKFLG FWLFLGGETV LFASLFATYL ALKDKTNGGP 

        70         80         90        100        110        120 
SAEELFQMPV VFMATMLLLT SSLTSVYAIY HMKNFDFKKM QLWFGITVLL GAGFLGLEIY 

       130        140        150        160        170        180 
EFNEYVHEGH KFTTSAFASA FYTLVGTHGS HVAFGLLWIL TLMIRNAKRG LNLYNAPKFY 

       190        200 
VASLYWHFID VVWVFIFTVV YLMGMVG 

« Hide

References

[1]"Nucleotide sequence of the gene coding for four subunits of cytochrome c oxidase from the thermophilic bacterium PS3."
Ishizuka M., Machida K., Shimada S., Mogi A., Tsuchiya T., Ohmori T., Souma Y., Gonda M., Sone N.
J. Biochem. 108:866-873(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-16.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D13955 Genomic DNA. Translation: BAA03047.1.

3D structure databases

ProteinModelPortalQ03439.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_BACP3
AccessionPrimary (citable) accession number: Q03439
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families