Q03425 (GSTZ2_DIACA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutathione S-transferase 2
EC=2.5.1.18

Alternative name(s):
GST class-zeta

Gene names

Name:

GST2

Organism

Dianthus caryophyllus (Carnation) (Clove pink)

Taxonomic identifier

3570 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › Caryophyllales › Caryophyllaceae › Dianthus

Protein attributes

Sequence length	145 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Developmental stage	Senescing flowers.
Induction	Accumulates in response to the phytohormone ethylene.
Sequence similarities	Belongs to the GST superfamily. Zeta family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Molecular function	Transferase
Gene Ontology (GO)
Biological_process	aromatic amino acid family metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›145	›145	Glutathione S-transferase 2		PRO_0000186032
Regions
	Domain	7 – 88	82	GST N-terminal
	Domain	93 – ›145	›53	GST C-terminal
	Region	17 – 22	6	Glutathione binding By similarity
	Region	72 – 73	2	Glutathione binding By similarity
	Region	116 – 118	3	Glutathione binding By similarity
Sites
	Binding site	60	1	Glutathione; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	112	1	Glutathione By similarity
Experimental info
	Non-terminal residue	145	1

Sequences

	Sequence		Length	Mass (Da)
	Q03425 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: EEF49C6143D796B3	FASTA	145	16,447
	10 20 30 40 50 60 MSSSETQKMQ LYSYSSSSCA WRVRIALHLK GLDFEYKAVD LLKGEHLTPE FLKLNPLGYV 70 80 90 100 110 120 PALVHGDIVI ADSLAIIMYL EEKFPENPLL PRDLQKRALN YQAANIVASN IQPFQNLAVL 130 140 NYIEEKLGSD EKLSWANHHI KKGFS

References

[1]	"Characterization of an ethylene-responsive glutathione S-transferase gene cluster in carnation." Itzhaki H., Woodson W.R. Plant Mol. Biol. 22:43-58(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. White Sim. Tissue: Petal.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L05916 Genomic DNA. Translation: AAA51450.1.
PIR	S33629.
3D structure databases
ProteinModelPortal	Q03425.
SMR	Q03425. Positions 8-115.
ModBase	Search...
Proteomic databases
PRIDE	Q03425.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.20.1050.10. 1 hit. 3.40.30.10. 1 hit.
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR005955. Mal_ac_isom. IPR012336. Thioredoxin-like_fold. [Graphical view]
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMs	TIGR01262. maiA. 1 hit.
PROSITE	PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GSTZ2_DIACA

Accession

Primary (citable) accession number: Q03425

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	April 3, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program