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Protein

Glutathione S-transferase 2

Gene

GST2

Organism
Dianthus caryophyllus (Carnation) (Clove pink)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei60Glutathione; via amide nitrogen and carbonyl oxygenBy similarity1
Binding sitei112GlutathioneBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase 2 (EC:2.5.1.18)
Alternative name(s):
GST class-zeta
Gene namesi
Name:GST2
OrganismiDianthus caryophyllus (Carnation) (Clove pink)
Taxonomic identifieri3570 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesCaryophyllaceaeCaryophylleaeDianthus

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001860321 – ›145Glutathione S-transferase 2Add BLAST›145

Expressioni

Developmental stagei

Senescing flowers.

Inductioni

Accumulates in response to the phytohormone ethylene.

Structurei

3D structure databases

ProteinModelPortaliQ03425
SMRiQ03425
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 88GST N-terminalAdd BLAST82
Domaini93 – ›145GST C-terminalAdd BLAST›53

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni17 – 22Glutathione bindingBy similarity6
Regioni72 – 73Glutathione bindingBy similarity2
Regioni116 – 118Glutathione bindingBy similarity3

Sequence similaritiesi

Belongs to the GST superfamily. Zeta family.Curated

Family and domain databases

CDDicd03042 GST_N_Zeta, 1 hit
InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR005955 GST_Zeta
IPR034333 GST_Zeta_N
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF13417 GST_N_3, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR01262 maiA, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Fragment.

Q03425-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSETQKMQ LYSYSSSSCA WRVRIALHLK GLDFEYKAVD LLKGEHLTPE
60 70 80 90 100
FLKLNPLGYV PALVHGDIVI ADSLAIIMYL EEKFPENPLL PRDLQKRALN
110 120 130 140
YQAANIVASN IQPFQNLAVL NYIEEKLGSD EKLSWANHHI KKGFS
Length:145
Mass (Da):16,447
Last modified:October 1, 1993 - v1
Checksum:iEEF49C6143D796B3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1451

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L05916 Genomic DNA Translation: AAA51450.1
PIRiS33629

Similar proteinsi

Entry informationi

Entry nameiGSTZ2_DIACA
AccessioniPrimary (citable) accession number: Q03425
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health