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Protein

Trafficking protein particle complex subunit 31

Gene

TRS31

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation.4 Publications

GO - Biological processi

  • autophagy Source: UniProtKB-KW
  • ER to Golgi vesicle-mediated transport Source: SGD
  • positive regulation of GTPase activity Source: GOC
Complete GO annotation...

Keywords - Biological processi

Autophagy, ER-Golgi transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29999-MONOMER.
ReactomeiR-SCE-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Trafficking protein particle complex subunit 31
Short name:
TRAPP subunit 31
Alternative name(s):
Transport protein particle 31 kDa subunit
Gene namesi
Name:TRS31
Ordered Locus Names:YDR472W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR472W.
SGDiS000002880. TRS31.

Subcellular locationi

GO - Cellular componenti

  • endoplasmic reticulum Source: UniProtKB-SubCell
  • pre-autophagosomal structure Source: UniProtKB-SubCell
  • TRAPPIII protein complex Source: SGD
  • TRAPPII protein complex Source: SGD
  • TRAPPI protein complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002115851 – 283Trafficking protein particle complex subunit 31Add BLAST283

Proteomic databases

MaxQBiQ03337.
PRIDEiQ03337.

PTM databases

iPTMnetiQ03337.

Interactioni

Subunit structurei

Part of the multisubunit TRAPP (transport protein particle) I complex composed of BET3, BET5, TRS20, TRS23, TRS31 and TRS33. Part of the multisubunit TRAPP (transport protein particle) II complex composed of BET3, BET5, TRS20, TRS23, TRS31, TRS33, TRS65, TRS85, TRS120 and TRS130. Part of the multisubunit TRAPP (transport protein particle) III complex composed of BET3, BET5, TRS20, TRS23, TRS31, TRS33 and TRS85.4 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
BET3P3614913EBI-38770,EBI-3567
TRS20P383345EBI-38770,EBI-19468

Protein-protein interaction databases

BioGridi32525. 57 interactors.
DIPiDIP-1709N.
IntActiQ03337. 10 interactors.
MINTiMINT-401389.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3CUEX-ray3.70B/H/N/T1-283[»]
ProteinModelPortaliQ03337.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ03337.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00390000000976.
HOGENOMiHOG000176758.
InParanoidiQ03337.
KOiK20280.
OrthoDBiEOG092C42ZV.

Family and domain databases

CDDicd14943. TRAPPC5_Trs31. 1 hit.
InterProiIPR024096. NO_sig/Golgi_transp_ligand-bd.
IPR016696. TRAPP-I_su5.
IPR007194. TRAPP_component.
[Graphical view]
PANTHERiPTHR20902. PTHR20902. 2 hits.
PfamiPF04051. TRAPP. 1 hit.
[Graphical view]
PIRSFiPIRSF017479. TRAPP_I_complex_Trs31. 1 hit.
SUPFAMiSSF111126. SSF111126. 2 hits.

Sequencei

Sequence statusi: Complete.

Q03337-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQRIIQPSA SDQQFPGKSD GYEYTVGPKQ AITSEASTTY IPSRIYSESL
60 70 80 90 100
LFKRQEASLS AMAFLFQEMI SQLHRTCKTA GDFETKLSDY GHNIGIRLLE
110 120 130 140 150
LLNFRASVSP SSLPRASAFL SQNESSSKLS NASNSPGMLA NSSTATSASA
160 170 180 190 200
NERLQEKQTE SLSNYITKMR RRDLKILDIL QFIHGTLWSY LFNHVSDDLV
210 220 230 240 250
KSSERDNEYM IVDNFPTLTQ FIPGENVSCE YFVCGIIKGF LFNAGFPCGV
260 270 280
TAHRMPQGGH SQRTVYLIQF DRQVLDREGL RFG
Length:283
Mass (Da):31,722
Last modified:November 1, 1996 - v1
Checksum:i857BBA3E03423D42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33050 Genomic DNA. Translation: AAB64914.1.
BK006938 Genomic DNA. Translation: DAA12306.1.
PIRiS69639.
RefSeqiNP_010760.3. NM_001180780.3.

Genome annotation databases

EnsemblFungiiYDR472W; YDR472W; YDR472W.
GeneIDi852083.
KEGGisce:YDR472W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33050 Genomic DNA. Translation: AAB64914.1.
BK006938 Genomic DNA. Translation: DAA12306.1.
PIRiS69639.
RefSeqiNP_010760.3. NM_001180780.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3CUEX-ray3.70B/H/N/T1-283[»]
ProteinModelPortaliQ03337.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32525. 57 interactors.
DIPiDIP-1709N.
IntActiQ03337. 10 interactors.
MINTiMINT-401389.

PTM databases

iPTMnetiQ03337.

Proteomic databases

MaxQBiQ03337.
PRIDEiQ03337.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR472W; YDR472W; YDR472W.
GeneIDi852083.
KEGGisce:YDR472W.

Organism-specific databases

EuPathDBiFungiDB:YDR472W.
SGDiS000002880. TRS31.

Phylogenomic databases

GeneTreeiENSGT00390000000976.
HOGENOMiHOG000176758.
InParanoidiQ03337.
KOiK20280.
OrthoDBiEOG092C42ZV.

Enzyme and pathway databases

BioCyciYEAST:G3O-29999-MONOMER.
ReactomeiR-SCE-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Miscellaneous databases

EvolutionaryTraceiQ03337.
PROiQ03337.

Family and domain databases

CDDicd14943. TRAPPC5_Trs31. 1 hit.
InterProiIPR024096. NO_sig/Golgi_transp_ligand-bd.
IPR016696. TRAPP-I_su5.
IPR007194. TRAPP_component.
[Graphical view]
PANTHERiPTHR20902. PTHR20902. 2 hits.
PfamiPF04051. TRAPP. 1 hit.
[Graphical view]
PIRSFiPIRSF017479. TRAPP_I_complex_Trs31. 1 hit.
SUPFAMiSSF111126. SSF111126. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiTRS31_YEAST
AccessioniPrimary (citable) accession number: Q03337
Secondary accession number(s): D6VT96
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 8350 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.